7 completed. 5 Not applicable, 2 Phase 2.
By phase and status
Follow Lederle Laboratories: new trials by email
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|
A Randomized, Double-Blind, Placebo Controlled Study of l-Leucovorin in Combination With Trimethoprim / Sulfamethoxazole in the Therapy of Pneumocystis Carinii Pneumonia in Patients With the Acquired Immunodeficiency Syndrome
Trimethoprim, Sulfamethoxazole, Leucovorin calcium - Pneumonia, Pneumocystis Carinii, HIV Infections | Not applicable | Completed | Lederle Laboratories | | | 2005-06-24 |
A Multi-Center, Open-Label, Ascending, Multiple Oral Dose, Safety, Tolerance and Pharmacokinetic Study of 3'-Deoxy-3'-Fluorothymidine (FLT) in Patients With Acquired Immune Deficiency Syndrome (AIDS) or AIDS-Related Complex (ARC)
Alovudine - HIV Infections | Not applicable | Completed | Lederle Laboratories | | | 2005-06-24 |
Phase II Study of Novantrone(R) (Mitoxantrone) and Etoposide in Patients With HIV Associated Large Cell and Immunoblastic Lymphomas
Mitoxantrone hydrochloride, Etoposide - Lymphoma, Non-Hodgkin, HIV Infections | Phase 2 | Completed | Lederle Laboratories | | | 2005-06-24 |
Preventive Treatment Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Confirmed Latent Tuberculous Infection
Isoniazid, Pyrazinamide, Pyridoxine hydrochloride - HIV Infections, Tuberculosis | Not applicable | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 2000 | | 2021-11-02 |
An Ascending, Single Oral Dose Pharmacokinetic Study of 3'-Deoxy-3'-Fluorothymidine (FLT) in Asymptomatic Human Immunodeficiency Virus (HIV)-Infected Subjects
Alovudine - HIV Infections | Not applicable | Completed | Lederle Laboratories | | | 2005-06-24 |
Phase II Study of Intravenous Novantrone(R) in the Treatment of AIDS Related Kaposi's Sarcoma
Mitoxantrone hydrochloride - Sarcoma, Kaposi, HIV Infections | Phase 2 | Completed | Lederle Laboratories | | | 2005-06-24 |
An Open-Label, Crossover Study to Assess the Effect of Food on the Oral Bioavailability and Pharmacokinetic Profile of 3'-Deoxy-3'-Fluorothymidine (FLT) in Asymptomatic Human Immunodeficiency Virus (HIV)-Infected Subjects
Alovudine - HIV Infections | Not applicable | Completed | Lederle Laboratories | | | 2005-06-24 |
Conditions studied
HIV Infections (7) · Acquired Immunodeficiency Syndrome (5) · AIDS-Related Opportunistic Infections (2) · AIDS-Related Complex (1) · Dendritic Cell Sarcoma, Interdigitating (1) · Lymphoma, Non-Hodgkin (1) · Pneumonia, Pneumocystis (1) · Sarcoma, Kaposi (1) · Tuberculosis (1)
Interventions
alovudine (3) · Mitoxantrone (2) · Etoposide (1) · Isoniazid (1) · Leucovorin (1) · Pyrazinamide (1) · Pyridoxine (1) · Rifampin (1) · Sulfamethoxazole (1) · Trimethoprim (1)
Countries
United States (7) · Puerto Rico (1)
Top investigators
Chaisson R (1)