8 completed, 1 not yet recruiting. 4 Not applicable, 3 Phase 2, 1 Phase 1, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 3, Not yet recruiting 1 |
| Phase 2 | 3 | Completed 3 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Sterile Normal Saline: new trials by email Literature Review of Sterile Normal Saline trials Research Report on Sterile Normal Saline
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Standard- and Micro-Dose rhBMP-2 for Implant Stability, Marginal Bone Loss, and Postoperative Sequelae: A Double-Blind Randomized Controlled Trial Standard-dose rhBMP-2, Micro-dose rhBMP-2, Sterile Normal Saline - Tooth Loss / Rehabilitation, Dental Implant | Not applicable | Not yet recruiting | University of Baghdad | 60 | 2026-12-01 | 2026-07-10 |
| Randomized Double-Blind Phase 2 Study of Allogeneic HB-adMSCs for the Treatment of Chronic Post-COVID-19 Syndrome HB-adMSCs (allogeneic), Placebo - Post COVID-19 Syndrome | Phase 2 | Completed | Hope Biosciences Research Foundation | 79 | 2022-02-02 | 2025-09-26 |
| Role of Branched-chain Amino Acids Infusion as Adjunct Therapy Post Liver Surgery for Patients in Intensive Care Unit BCAA preparation Intravenous infusion, sterile normal saline - Liver Function Post BCAA Infusion | Not applicable | Completed | National Hepatology & Tropical Medicine Research Institute | 60 | 2018-03-15 | 2021-02-21 |
| Memory Aid by Intranasal Insulin in Diabetes (MemAID) Regular Human Insulin, Placebo - Type 2 Diabetes Mellitus | Phase 2 | Completed | Beth Israel Deaconess Medical Center | 289 | 2015-10-06 | 2022-05-19 |
| 2 Dose Neuraxial Morphine for Prevention of PDPH Morphine, Sterile normal saline - Postdural Puncture Headache | Phase 4 | Completed | Columbia University | 44 | 2015-09-01 | 2025-02-05 |
| Safety Study of AEM-28 to Treat Refractory Hypercholesterolemia AEM-28, Normal Saline - Hypercholesterolemia, Hyperlipoproteinemia Type II | Phase 1 / Phase 2 | Completed | LipimetiX Development, LLC | 52 | 2014-03-01 | 2015-12-29 |
| Optimizing Patient Analgesic Experience During IVF Lidocaine hydrochloride (HCl) 1% solution, Sterile Normal Saline% - Infertility | Not applicable | Completed | University of Alberta | 308 | 2013-03-01 | 2022-07-18 |
| Transversus Abdominis Plane (TAP) Block Laparoscopic Hysterectomy Placebo, Drug .5% Ropivacaine, 20 cc of 0.25% ropivacaine - Postoperative Pain | Not applicable | Completed | Northwestern University | 75 | 2010-03-01 | 2014-05-08 |
| Efficacy and Safety of Intraarticular Injections of Hyalgan in the Treatment of Osteoarthritis of the Knee Hyalgan, sterile normal saline - Osteoarthritis | Phase 3 | Completed | Med Pharma Co., Ltd. | 200 | 2001-05-01 | 2011-03-25 |
Diabetes Mellitus, Type 2 (1) · Hypercholesterolemia (1) · Hyperlipoproteinemia Type II (1) · Infertility (1) · Osteoarthritis (1) · Pain (1) · Pain, Postoperative (1) · Post-Acute COVID-19 Syndrome (1) · Post-Dural Puncture Headache (1) · Tooth Loss (1)
Beth Israel Deaconess Medical Center (1) · Columbia University (1) · Hope Biosciences Research Foundation (1) · LipimetiX Development, LLC (1) · Med Pharma Co., Ltd. (1) · National Hepatology & Tropical Medicine Research Institute (1) · Northwestern University (1) · University of Alberta (1) · University of Baghdad (1)
United States (4) · Australia (1) · Canada (1) · Egypt (1) · Iraq (1) · Taiwan (1)
Gildasio DeOliveira, MD (1) · Janakan Krishnarajah, MBBS, FRACP (1) · Lin Ching Tsai, PhD (1) · Peter Novak, MD PhD (1) · Richard Smiley, MD, PhD (1) · Tarek Motan, MB ChB (1) · Thanh Cheng, MD (1) · Vera Novak, MD PhD (1)
PMID 21978211, PMID 22105251, PMID 33792960, PMID 35482079, PMID 36539060, PMID 40537743
R01DK103902 (1)