10 completed, 2 recruiting, 1 not yet recruiting, 1 terminated. 16 Phase 2, 3 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 16 | Completed 10, Recruiting 2, Not yet recruiting 1, Terminated 1, Unknown 1, Withdrawn 1 |
| Phase 1 | 3 | Recruiting 2, Withdrawn 1 |
| Phase 3 | 1 | Completed 1 |
Follow roxadustat: new trials by email Literature Review of roxadustat trials Research Report on roxadustat
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Roxadustat on Renal Oxygenation in Diabetes Nephropathy Roxadustat, Darbepoietin Alfa - Diabetes Complications, Diabetes; Nephropathy (Manifestation) | Phase 2 | Not yet recruiting | Region Stockholm | 30 | 2025-06-01 | 2024-11-19 |
| Roxadustat for Bone and Neuropsychiatric Aspects in Hemodialysis Patients Roxadustat, Conventional Anemia Management - Kidney Failure,Chronic, Anemia in End Stage Renal Disease | Phase 1 / Phase 2 | Recruiting | Mansoura University | 46 | 2025-04-15 | 2025-05-11 |
| Roxadustat's Effect on Heart, Nutrition, and Inflammation in Hemodialysis Patients Roxadustat, Conventional Anemia Management - Kidney Failure, Chronic, Malnutrition-Inflammation Syndrome | Phase 1 / Phase 2 | Recruiting | Mansoura University | 46 | 2025-04-15 | 2025-05-13 |
| A Single-arm Trial of Roxadustat Combined With Retinoic Acid in the Treatment of Refractory Low-risk MDS Roxadustat in combination with retinoic acid - Myelodysplastic Syndromes | Phase 1 / Phase 2 | Withdrawn | Peking Union Medical College Hospital | 2023-08-01 | 2026-07-07 | |
| Study of Roxadustat for Reducing the Incidence of Acute Kidney Injury After Coronary Artery Bypass Grafting Roxadustat, Placebo - Coronary Artery Bypass | Phase 2 | Terminated | Peking Union Medical College Hospital | 98 | 2021-09-30 | 2025-12-09 |
| Study of Roxadustat in the Treatment of Acute Myocardial Infarction Roxadustat - ST Elevation Myocardial Infarction | Phase 2 | Unknown | Ruijin Hospital | 158 | 2021-06-10 | 2021-09-01 |
| Evaluation of Efficacy and Safety of Roxadustat for the Treatment of Chemotherapy Induced Anemia Roxadustat - Chemotherapy Induced Anemia | Phase 2 | Completed | Kyntra Bio | 92 | 2019-08-20 | 2022-06-03 |
| Efficacy and Safety of FG-4592 for Treatment of Anemia in Participants With Lower Risk Myelodysplastic Syndrome (MDS) FG-4592, Placebo - Anemia, Myelodysplastic Syndrome | Phase 2 / Phase 3 | Completed | Kyntra Bio | 43 | 2018-06-06 | 2023-05-03 |
| A Study to Investigate the Effect of ASP1517 After Intermittent Oral Dosing in Dialysis Chronic Kidney Disease Patients With Anemia Compared With Darbepoetin as a Reference Drug roxadustat, darbepoetin alfa - Renal Anemia Associated With Chronic Renal Failure (CRF) | Phase 2 | Completed | Astellas Pharma Inc | 130 | 2013-03-28 | 2024-10-30 |
| Open-Label Extension Study for the Long-Term Efficacy and Safety of Roxadustat in Participants With Dialysis and Non-Dialysis Chronic Kidney Disease Roxadustat - Chronic Kidney Disease, End Stage Renal Disease | Phase 2 | Completed | Kyntra Bio | 15 | 2012-05-18 | 2021-10-01 |
| Study of FG-4592 in Subjects With Chronic Kidney Disease in China FG-4592, Placebo - Anemia in Chronic Kidney Disease | Phase 2 | Completed | Kyntra Bio | 91 | 2011-12-01 | 2014-03-03 |
| Study of FG-4592 in Subjects With End-Stage Renal Disease Receiving Maintenance Hemodialysis in China FG-4592, Epoetin Alfa - Anemia in End Stage Renal Disease | Phase 2 | Completed | Kyntra Bio | 96 | 2011-09-01 | 2013-02-04 |
| Study of Roxadustat (FG-4592) to Correct Anemia in Newly Initiated Dialysis Participants Not on Erythropoiesis-Stimulating Agent Treatment Roxadustat, Oral Iron, IV Iron - Dialysis, Anemia | Phase 2 | Completed | Kyntra Bio | 60 | 2011-07-21 | 2021-10-01 |
| Study of Roxadustat in Non-Dialysis Chronic Kidney Disease Participants With Anemia Roxadustat - Chronic Kidney Disease, Anemia | Phase 2 | Completed | Kyntra Bio | 145 | 2010-10-29 | 2022-02-10 |
| Study of Roxadustat (FG-4592) in Participants With End-Stage Renal Disease Receiving Maintenance Hemodialysis Roxadustat, Epoetin Alfa, Placebo - End Stage Renal Disease, Anemia | Phase 2 | Completed | Kyntra Bio | 161 | 2010-05-17 | 2022-01-11 |
| Phase 2 Study of Roxadustat in Participants With Anemia and Chronic Kidney Disease Not Requiring Dialysis Roxadustat, Placebo - Chronic Kidney Disease, Anemia | Phase 2 | Completed | Kyntra Bio | 117 | 2006-11-01 | 2021-11-19 |
Anemia (9) · Kidney Failure, Chronic (6) · Renal Insufficiency, Chronic (4) · Myelodysplastic Syndromes (2) · Acute Kidney Injury (1) · Cardiovascular Diseases (1) · Diabetes Complications (1) · Diabetes Mellitus (1) · Hypoxia (1) · Kidney Diseases (1) · ST Elevation Myocardial Infarction (1)
Kyntra Bio (9) · Mansoura University (2) · Peking Union Medical College Hospital (2) · Astellas Pharma Inc (1) · Region Stockholm (1) · Ruijin Hospital (1)
United States (6) · China (5) · Egypt (2) · Puerto Rico (2) · Hong Kong (1) · Japan (1) · Russia (1) · Singapore (1) · Sweden (1)
Marietta Franco (1) · Peony Yu (1) · Qi Miao, Doctor (1) · Ruiyan Zhang, M.D., Ph.D. (1) · Sergiu Catrina, Ass. Proff. (1) · Yan Qin, Doctor (1)