620 completed, 359 recruiting, 324 active not recruiting, 151 terminated. 657 Not applicable, 434 Phase 2, 177 Phase 3, 141 Phase 1, 38 Early Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Safety and Feasibility of Immunotherapy Drugs, Botensilimab and Balstilimab, Before Surgery for Clear Cell Renal Cell Carcinoma, NEO RoBOT Trial Balstilimab, Biospecimen Collection, Botensilimab - Clear Cell Renal Cell Carcinoma, Stage II Renal Cell Cancer AJCC v8 | Phase 2 | Recruiting | National Cancer Institute (NCI) | 16 | 2027-05-17 | 2026-10-21 |
| Incidence of HPV Infection and HPV-Associated Disease in Screening Indian Men Who Have Sex With HIV-Positive Men Cytology Specimen Collection Procedure, High Resolution Anoscopy with Biopsy, Laboratory Biomarker Analysis - HIV Infection, Human Papillomavirus Infection | Withdrawn | AIDS Malignancy Consortium | 2027-04-30 | 2025-06-06 | ||
| Incidence of HIV Infection in Screening Indian Men Who Have Sex With Men Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis, Medical Examination - HIV Infection | Withdrawn | AIDS Malignancy Consortium | 2027-04-30 | 2025-06-06 | ||
| Prehabilitation for Improving Outcomes in Breast Cancer Patients Undergoing Neoadjuvant Systemic Treatment and Surgery Aerobic Exercise, Bioelectric Impedance Analysis, Consultation - Breast Carcinoma | Not applicable | Not yet recruiting | City of Hope Medical Center | 20 | 2027-02-24 | 2026-09-15 |
| A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients Dietary Fiber, Enema Administration, Loperamide Hydrochloride - Low Anterior Resection Syndrome, Rectal Carcinoma | Not applicable | Recruiting | Ohio State University Comprehensive Cancer Center | 80 | 2027-02-15 | 2026-10-06 |
| The High Fiber Program to Increase Fiber Intake Among Patients Undergoing Allogeneic Hematopoietic Cell Transplant Biospecimen Collection, Dietary Intervention, Questionnaire Administration - Hematopoietic and Lymphatic System Neoplasm | Not applicable | Not yet recruiting | City of Hope Medical Center | 44 | 2027-02-13 | 2026-08-31 |
| Low Dose Aspirin to Lower Inflammation and Prevent Endometrial Cancer in Postmenopausal Women With Non-atrophic Endometrial Changes and Pain Biospecimen Collection, Low-Dose Aspirin, Patient Observation - Endometrial Carcinoma | Phase 4 | Not yet recruiting | Mayo Clinic | 20 | 2027-02-12 | 2026-08-05 |
| Improving Processes of Cancer Care Delivery at a Comprehensive Cancer Center Discussion, Electronic Health Record Review, Questionnaire Administration - Metastatic Malignant Solid Neoplasm | Not yet recruiting | M.D. Anderson Cancer Center | 200 | 2027-01-30 | 2026-09-11 | |
| Comparing Radiation After Surgery to Observation After Surgery in Patients With Clinical Low-Risk, Molecular High-Risk Meningioma, and Evaluating Observation After Surgery in Patients With Clinical and Molecular Low-Risk Meningioma Patient Observation, Magnetic Resonance Imaging, Biospecimen Collection - Grade 1 Meningioma, Grade 2 Meningioma | Phase 3 | Not yet recruiting | NRG Oncology | 464 | 2027-01-28 | 2026-08-25 |
| Cannabis Gummy for the Improvement of Sleep and Quality of Life in Patients With Cancer, Pillow Trial Actigraphy, Best Practice, Biospecimen Collection - Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm | Phase 1 / Phase 2 | Not yet recruiting | Theodore Brasky PhD | 50 | 2027-01-15 | 2026-10-14 |
| Testing the Use of High Dose Testosterone Followed by Darolutamide Compared to the Usual Care for Patients With Metastatic Prostate Cancer Abiraterone Acetate, Biospecimen Collection, Bone Scan - Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 / Phase 3 | Not yet recruiting | ECOG-ACRIN Cancer Research Group | 432 | 2027-01-06 | 2026-10-01 |
| Belinostat in Combination With Azacitidine or Pralatrexate for the Treatment of Relapse or Refractory T-cell Lymphoma Azacitidine, Belinostat, Biospecimen Collection - Recurrent Anaplastic Large Cell Lymphoma, Recurrent Enteropathy-Associated T-Cell Lymphoma | Phase 1 | Not yet recruiting | City of Hope Medical Center | 40 | 2027-01-03 | 2026-07-09 |
| Magnetic Resonance-Guided Stereotactic Body Radiation Therapy for the Treatment of Prostate Cancer Biopsy Procedure, Computed Tomography, Electronic Health Record Review - Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8 | Not applicable | Not yet recruiting | City of Hope Medical Center | 20 | 2027-01-01 | 2026-08-17 |
| Adoption of Audio Recording in the Outpatient Supportive Care Center Communication Intervention, Questionnaire Administration - Advanced Malignant Solid Neoplasm, Hematopoietic and Lymphoid Cell Neoplasm | Not yet recruiting | M.D. Anderson Cancer Center | 200 | 2026-12-30 | 2026-07-16 | |
| Circadian-Optimized Light Therapy for the Treatment of Patients With Advanced Melanoma Receiving Tumor-Infiltrating Lymphocyte Therapy Biospecimen Collection, Internet-Based Intervention, Medical Device Usage and Evaluation - Advanced Cutaneous Melanoma, Clinical Stage III Cutaneous Melanoma AJCC v8 | Phase 1 | Not yet recruiting | City of Hope Medical Center | 8 | 2026-12-23 | 2026-06-05 |
| Elacestrant With Everolimus for the Treatment of Recurrent Advanced or Metastatic ER-Positive Endometrial Cancer Biospecimen Collection, Computed Tomography, Elacestrant - Advanced Endometrial Carcinoma, Metastatic Endometrial Carcinoma | Phase 2 | Not yet recruiting | Jonsson Comprehensive Cancer Center | 50 | 2026-12-18 | 2026-06-09 |
| Testing the Effects of Exercise on Colorectal Cancer Development After Treatment With Pelvic Radiation Therapy for Prostate Cancer Aerobic Exercise, Biopsy Procedure, Biospecimen Collection - Colon Polyp, Colorectal Carcinoma | Not applicable | Recruiting | City of Hope Medical Center | 30 | 2026-12-16 | 2026-08-28 |
| Tear Fluid for the Detection of Tumor-associated Extracellular Vesicles in Glioblastoma Patients Biospecimen Collection, Electronic Health Record Review, Questionnaire Administration - Glioblastoma | Not applicable | Recruiting | City of Hope Medical Center | 30 | 2026-12-09 | 2026-10-08 |
| Minimally Invasive Approaches for the Diagnosis of Barrett's Esophagus and Esophageal Cancer, SOS5C Trial Cancer Screening, Computer-Assisted Intervention, Endoscopic Procedure - Barrett Esophagus, Esophageal Adenocarcinoma | Not applicable | Not yet recruiting | Mayo Clinic | 1010 | 2026-12-01 | 2026-06-24 |
| Escalating Cycle 1 Dose of Lu-177-PSMA-617 for the Treatment of Metastatic Castration Resistant Prostate Cancer Biospecimen Collection, Computed Tomography, Gallium Ga 68 Gozetotide - Metastatic Castration-Resistant Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 1 | Not yet recruiting | University of Michigan Rogel Cancer Center | 20 | 2026-12-01 | 2026-10-15 |
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Breast Neoplasms (229) · Prostatic Neoplasms (154) · Lung Neoplasms (107) · Neoplasms (94) · Colorectal Neoplasms (79) · Hematologic Neoplasms (67) · Carcinoma, Non-Small-Cell Lung (66) · Ovarian Neoplasms (53) · Breast Carcinoma In Situ (51) · Neoplasm Metastasis (50) · Pain (50) · Leukemia, Myeloid, Acute (49) · Multiple Myeloma (46) · Uterine Cervical Neoplasms (43) · Colonic Neoplasms (42)
M.D. Anderson Cancer Center (252) · City of Hope Medical Center (163) · Mayo Clinic (163) · National Cancer Institute (NCI) (111) · Ohio State University Comprehensive Cancer Center (93) · Fred Hutchinson Cancer Center (68) · Roswell Park Cancer Institute (67) · Children's Oncology Group (52) · Wake Forest University Health Sciences (52) · Jonsson Comprehensive Cancer Center (47) · University of Southern California (41) · University of Washington (37) · Alliance for Clinical Trials in Oncology (36) · OHSU Knight Cancer Institute (36) · Emory University (25)
United States (1531) · Canada (91) · Puerto Rico (65) · United Kingdom (56) · Australia (29) · New Zealand (14) · Guam (11) · Switzerland (11) · South Korea (10) · France (9) · Italy (9) · Ireland (7) · Japan (7) · Netherlands (7) · Germany (5)
Charles Loprinzi (10) · Virginia Sun (10) · David Hui (9) · Lorenzo Cohen (9) · Sriram Yennu (9) · Kathrin Milbury (7) · Paul Pharoah, MD (7) · Anurag K Singh (6) · Lorna McNeill (6) · Amar Kishan (5) · Marcia Grant, RN, DNSc, FAAN (5) · Mark Emberton, MD, FRCS, MBBS (5) · Richard T Lee (5) · Sarah Prinsloo (5) · Smita Bhatia (5)
PMID 37505794, PMID 33395032, PMID 34036820, PMID 34616010, PMID 36184192, PMID 38421243, PMID 38603649, PMID 39571596, PMID 41170811, PMID 41276263, PMID 41920422, PMID 42335416, PMID 18799354, PMID 19508716, PMID 19967408, PMID 20354183, PMID 20496155, PMID 21271347, PMID 21334018, PMID 21393334, PMID 21631324, PMID 21941283, PMID 21994964, PMID 22067707, PMID 22105720, PMID 22204725, PMID 22277551, PMID 22512844, PMID 22795905, PMID 22827973, PMID 23011914, PMID 23079177, PMID 23217054, PMID 23273589, PMID 23388559, PMID 23395006, PMID 23433098, PMID 23518928, PMID 23523362, PMID 23575918, PMID 23598171, PMID 23796741, PMID 24001635, PMID 24004815, PMID 24067488, PMID 24099865, PMID 24279296, PMID 24291380, PMID 24552320, PMID 24590745
P30CA033572 (108), P30CA015704 (38), P30CA012197 (33), P30CA014089 (33), U10CA180868 (33), P30CA016672 (32), P30CA015083 (28), U10CA180886 (28), P30CA138292 (24), P30CA060553 (23), U10CA180821 (20), P30CA068485 (18), P30CA043703 (17), UG1CA189955 (17), U10CA180820 (16)