8 recruiting, 4 completed, 1 terminated, 1 withdrawn. 14 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 14 | Recruiting 8, Completed 4, Terminated 1, Withdrawn 1 |
Follow Pt: new trials by email Literature Review of Pt trials Research Report on Pt
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Allogeneic CMV-Specific CD19-CAR T Cells Plus CMV-MVA Triplex Vaccine After Matched Related Donor Hematopoietic Cell Transplant for the Treatment of Patients With High-Risk Acute Lymphoblastic Leukemia Allogeneic Hematopoietic Stem Cell Transplantation, Anti-CD19-CAR CMV-specific T-lymphocytes, Biospecimen Collection - Acute Lymphoblastic Leukemia | Early Phase 1 | Recruiting | City of Hope Medical Center | 15 | 2025-12-30 | 2026-04-27 |
| Comparing a New PSMA Imaging Agent to MRI for Detecting Prostate Cancer, BEACON Trial Biopsy of Prostate, Biospecimen Collection, Computed Tomography - Prostate Carcinoma | Early Phase 1 | Recruiting | Jonsson Comprehensive Cancer Center | 30 | 2025-11-14 | 2026-03-10 |
| An Investigational Scan ([68Ga] Ga-FAPI-04 PET/CT) for the Imaging of Patients With High-Grade Neuroendocrine Cancer Computed Tomography, Gallium Ga 68-DOTA-FAPI-04, Positron Emission Tomography - Neuroendocrine Tumor | Early Phase 1 | Recruiting | University of Michigan Rogel Cancer Center | 30 | 2025-09-16 | 2026-07-31 |
| Medication Combinations of Dasatinib, Quercetin, Fisetin, Temozolomide, LMP744, and Autologous TLPO Vaccine for the Treatment of Previously Treated Glioma With Residual Disease Biospecimen Collection, Dasatinib, Fisetin - Glioma | Early Phase 1 | Recruiting | Mayo Clinic | 30 | 2025-08-12 | 2026-10-01 |
| An Investigational Scan (rhPSMA-7.3 PET/CT) for Detecting Biochemically Recurrent Prostate Cancer, ENLIGHTEN Trial Computed Tomography, Electronic Health Record Review, Flotufolastat F-18 Gallium - Biochemically Recurrent Prostate Carcinoma, Prostate Adenocarcinoma | Early Phase 1 | Recruiting | Northwestern University | 27 | 2025-04-11 | 2026-07-02 |
| Comparing an Investigational Scan (F-18 NaF PET/CT) to Standard of Care Imaging (F-18 FDG PET/CT) for Evaluating Vascular Complications in Patients Receiving Radiation Therapy for Head and Neck Cancer Computed Tomography, Fludeoxyglucose F-18, Intensity-Modulated Proton Therapy - Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Early Phase 1 | Recruiting | Emory University | 20 | 2024-12-03 | 2025-10-22 |
| 64Cu-DOTA Pembrolizumab for Imaging Metastatic Solid Tumors in Patients Receiving Stereotactic Body Radiation Copper Cu 64-DOTA-pembrolizumab, Positron Emission Tomography, Stereotactic Body Radiation Therapy - Metastatic Malignant Solid Neoplasm | Early Phase 1 | Withdrawn | City of Hope Medical Center | 2023-08-25 | 2023-10-10 | |
| Evaluation of Bridging Radiation Therapy Before CAR T-Cell Infusion for the Treatment of Relapsed or Refractory Large B-Cell Lymphoma Biospecimen Collection, Chimeric Antigen Receptor T-Cell Therapy, Computed Tomography - Recurrent Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell Lymphoma | Early Phase 1 | Recruiting | City of Hope Medical Center | 9 | 2023-07-20 | 2026-02-04 |
| rhPSMA-73 PET-MRI Imaging for the Detection of Prostate Cancer Among Men Who Are Otherwise Candidates for Active Surveillance Biopsy of Prostate, Decipher Prostate Cancer Test, Flotufolastat F-18 Gallium - Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8 | Early Phase 1 | Recruiting | Northwestern University | 40 | 2023-06-07 | 2026-07-02 |
| Radiation Therapy, Plasma Exchange, and Immunotherapy (Pembrolizumab or Nivolumab) for the Treatment of Melanoma Nivolumab, Pembrolizumab, Radiation Therapy - Melanoma | Early Phase 1 | Completed | Mayo Clinic | 18 | 2020-12-14 | 2025-07-10 |
| PSMA PET/MRI or PSMA PET/CT for Evaluation of Liver Cancer Biopsy, Computed Tomography, Gallium Ga 68 Gozetotide - Hepatocellular Carcinoma | Early Phase 1 | Completed | Mayo Clinic | 42 | 2020-06-05 | 2024-09-19 |
| Heated Intra-peritoneal Chemotherapy With Doxorubicin and Cisplatin for Abdominal for Pelvic Tumors in Pediatric Patients Cisplatin, Cytoreductive Surgery, Doxorubicin - Malignant Abdominal Neoplasm, Malignant Pelvic Neoplasm | Early Phase 1 | Terminated | Mayo Clinic | 2 | 2019-11-08 | 2025-02-20 |
| Imiquimod and Pembrolizumab in Treating Patients With Stage IIIB-IV Melanoma Imiquimod, Biopsy, Pembrolizumab - Metastatic Melanoma, Stage IIIB Cutaneous Melanoma AJCC v7 | Early Phase 1 | Completed | Mayo Clinic | 7 | 2017-12-20 | 2026-03-19 |
| TAME-PD - Physical Therapy, Atomoxetine and, Methylphenidate, to Enhance Gait and Balance in Parkinson's Disease Methylphenidate, Physical Therapy, Atomoxetine - Parkinson's Disease, Idiopathic | Early Phase 1 | Completed | Hubert Fernandez | 23 | 2017-01-03 | 2026-01-09 |
Melanoma (2) · Prostatic Neoplasms (2) · Carcinoma (1) · Carcinoma, Hepatocellular (1) · Colonic Neoplasms (1) · Desmoplastic Small Round Cell Tumor (1) · Fallopian Tube Neoplasms (1) · Glioma (1) · Hypopharyngeal Neoplasms (1) · Laryngeal Neoplasms (1) · Liposarcoma (1) · Lymphoma, Large B-Cell, Diffuse (1) · Mesothelioma, Malignant (1) · Neoplasm Metastasis (1) · Neuroendocrine Tumors (1)
Mayo Clinic (5) · City of Hope Medical Center (3) · Northwestern University (2) · Emory University (1) · Hubert Fernandez (1) · Jonsson Comprehensive Cancer Center (1) · University of Michigan Rogel Cancer Center (1)
United States (13)
Ashley E Ross (2) · Ajit H. Goenka, M.D. (1) · Amol M Takalkar, MD, MS, MBA, FACNM (1) · Benjamin Viglianti (1) · Hubert Fernandez (1) · Ibrahim Aldoss (1) · Jacob J. Orme, M.D., Ph.D. (1) · Patricio C. Gargollo, M.D. (1) · Ruqin Chen, MD, MB (1) · Sagus Sampath (1) · Savita V Dandapani (1) · Sean S. Park, M.D., Ph.D. (1) · Terence C. Burns, MD, PhD (1) · Wayne Brisbane (1)
PMID 35551087, PMID 40177325, PMID 41833067
P30CA033572 (3), P30CA060553 (2), P30CA138292 (1), R21CA259236 (1)