27 completed, 4 unknown, 3 withdrawn, 2 active not recruiting. 21 Phase 2, 15 Phase 3, 2 Not applicable, 2 Phase 1, 1 Early Phase 1.
Follow Procarbazine Hydrochloride: new trials by email Literature Review of Procarbazine Hydrochloride trials Research Report on Procarbazine Hydrochloride
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab Biospecimen Collection, Bleomycin Sulfate, Brentuximab Vedotin - Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8 | Phase 3 | Recruiting | National Cancer Institute (NCI) | 1875 | 2023-05-11 | 2026-10-22 |
| Intravenous Chemotherapy or Oral Chemotherapy in Treating Patients With Previously Untreated Stage III-IV HIV-Associated Non-Hodgkin Lymphoma cyclophosphamide, doxorubicin hydrochloride, vincristine sulfate - AIDS-related Diffuse Large Cell Lymphoma, AIDS-related Diffuse Mixed Cell Lymphoma | Phase 2 | Completed | AIDS Malignancy Consortium | 7 | 2016-09-15 | 2022-10-10 |
| Chemotherapy Based on Positron Emission Tomography Scan in Treating Patients With Stage I or Stage II Hodgkin Lymphoma Bleomycin Sulfate, Doxorubicin Hydrochloride, Procarbazine Hydrochloride - Lymphoma | Phase 2 | Completed | Alliance for Clinical Trials in Oncology | 164 | 2010-05-01 | 2021-06-14 |
| S0816 Fludeoxyglucose F 18-PET/CT Imaging and Combination Chemotherapy With or Without Additional Chemotherapy and G-CSF in Treating Patients With Stage III or Stage IV Hodgkin Lymphoma bleomycin sulfate, filgrastim, ABVD regimen - Lymphoma, Nonneoplastic Condition | Phase 2 | Completed | SWOG Cancer Research Network | 371 | 2009-07-01 | 2022-08-18 |
| Pilot Study of MGd + High-dose MTX-Based Chemoimmunotherapy + RT for Newly Dx PCNSL Rituximab, Cytarabine, Methotrexate - Brain and Central Nervous System Tumors, Lymphoma | Early Phase 1 | Withdrawn | Northwestern University | 2008-11-01 | 2012-05-18 | |
| Fludeoxyglucose F 18-PET/CT Imaging in Assessing Response to Chemotherapy in Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Hodgkin Lymphoma bleomycin sulfate, filgrastim, pegfilgrastim - Lymphoma | Phase 3 | Completed | University College, London | 1202 | 2008-08-29 | 2024-05-08 |
| Combination Chemotherapy in Treating Younger Patients With Hodgkin Lymphoma cyclophosphamide, doxorubicin hydrochloride, etoposide - Lymphoma, Neurotoxicity | Phase 2 | Completed | University College, London | 47 | 2008-03-01 | 2014-12-04 |
| Combination Chemotherapy Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or High-Risk Primary Refractory Hodgkin Lymphoma cyclophosphamide, cyclosporine, fludarabine phosphate - Lymphoma | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 25 | 2007-11-13 | 2023-09-28 |
| Rituximab and Combination Chemotherapy in Treating Patients With Primary Central Nervous System Lymphoma Rituximab, Cytarabine, Dexamethasone - Lymphoma | Phase 2 | Terminated | Eastern Cooperative Oncology Group | 26 | 2007-08-23 | 2023-07-03 |
| Combination Chemotherapy in Treating Young Patients With Hodgkin's Lymphoma cyclophosphamide, dacarbazine, prednisolone - Lymphoma | Phase 3 | Completed | Christine Mauz-Körholz | 2134 | 2007-01-01 | 2020-03-26 |
| Thalidomide and Procarbazine in Treating Patients With Recurrent or Progressive Malignant Glioma procarbazine hydrochloride, thalidomide - Brain and Central Nervous System Tumors | Phase 2 | Completed | Wake Forest University Health Sciences | 18 | 2004-01-01 | 2021-09-09 |
| A Phase II Study VEPEMB In Patients With Hodgkin's Lymphoma Aged ≥ 60 Years bleomycin sulfate, cyclophosphamide, etoposide - Lymphoma | Phase 2 | Completed | Newcastle-upon-Tyne Hospitals NHS Trust | 175 | 2004-01-01 | 2017-03-30 |
| Combination Chemotherapy and Radiation Therapy in Treating Young Patients With Hodgkin's Lymphoma cyclophosphamide, dacarbazine, doxorubicin hydrochloride - Lymphoma | Phase 2 | Completed | Christine Mauz-Körholz | 648 | 2002-11-01 | 2020-03-26 |
| Temozolomide Compared to Procarbazine, Lomustine, and Vincristine in Treating Patients With Recurrent Malignant Glioma lomustine, procarbazine hydrochloride, temozolomide - Brain and Central Nervous System Tumors | Phase 3 | Completed | Institute of Cancer Research, United Kingdom | 500 | 2002-10-01 | 2013-12-18 |
| Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Stage III or Stage IV Hodgkin's Lymphoma bleomycin sulfate, filgrastim, pegfilgrastim - Lymphoma | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 552 | 2002-08-01 | 2025-08-05 |
| Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors filgrastim, gene therapy, lomustine - Bone Marrow Suppression, Brain and Central Nervous System Tumors | Phase 1 | Completed | Indiana University | 10 | 2000-02-01 | 2015-03-25 |
| Combination Chemotherapy With or Without Radiation Therapy and Peripheral Stem Cell Transplant in Treating Children With Hodgkin's Lymphoma bleomycin sulfate, chlorambucil, cisplatin - Lymphoma | Phase 2 | Unknown | Children's Cancer and Leukaemia Group | 260 | 2000-01-01 | 2013-08-07 |
| Methotrexate, Procarbazine, Lomustine, Dexamethasone, and Cytarabine in Treating Patients With Primary CNS Lymphoma cytarabine, dexamethasone, lomustine - Lymphoma | Phase 2 | Completed | OHSU Knight Cancer Institute | 1 | 2000-01-01 | 2017-04-21 |
| Combination Chemotherapy and Radiation Therapy in Treating Children With Previously Untreated Stage II, Stage III, or Stage IV Hodgkin's Disease bleomycin sulfate, filgrastim, ABVD regimen - Lymphoma | Phase 2 | Completed | Children's Oncology Group | 99 | 1999-10-01 | 2014-02-26 |
| Procarbazine in Treating Patients With Recurrent Brain Tumor procarbazine hydrochloride - Brain and Central Nervous System Tumors | Phase 1 / Phase 2 | Completed | New Approaches to Brain Tumor Therapy Consortium | 1999-07-01 | 2013-06-21 |
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Lymphoma (23) · Central Nervous System Neoplasms (15) · Hodgkin Disease (12) · Astrocytoma (10) · Brain Neoplasms (9) · Oligodendroglioma (8) · Glioblastoma (7) · Gliosarcoma (7) · Glioma (5) · Recurrence (4) · Lymphoma, AIDS-Related (2) · Neurotoxicity Syndromes (2) · Burkitt Lymphoma (1) · Drug-Related Side Effects and Adverse Reactions (1) · Ependymoma (1)
Case Comprehensive Cancer Center (4) · European Organisation for Research and Treatment of Cancer - EORTC (4) · Children's Cancer and Leukaemia Group (3) · Alliance for Clinical Trials in Oncology (2) · Children's Oncology Group (2) · Christine Mauz-Körholz (2) · M.D. Anderson Cancer Center (2) · Memorial Sloan Kettering Cancer Center (2) · Radiation Therapy Oncology Group (2) · University College, London (2) · AIDS Malignancy Consortium (1) · Colorado Health Foundation (1) · Eastern Cooperative Oncology Group (1) · Indiana University (1) · Institute of Cancer Research, United Kingdom (1)
United States (21) · United Kingdom (9) · Canada (7) · Germany (4) · Netherlands (4) · Australia (3) · Belgium (3) · France (3) · Hungary (2) · Italy (2) · Kenya (2) · New Zealand (2) · Poland (2) · Portugal (2) · Sweden (2)
Scot C. Remick, MD (4) · Dieter Koerholz, MD (2) · Edward G. Shaw, MD (2) · Jan C. Buckner, MD (2) · Joann Ater, MD (2) · John Martin, MD (2) · A. Barratt, MD (1) · Alison L. Hannah, MBBS (1) · Andrew M. Evens, DO, MS (1) · Ann Barrett (1) · Anna Sureda (1) · Barry W. Hancock, MD (1) · Bengt Glimelius, MD (1) · Christophe Ferme (1) · David C. Linch (1)
PMID 40135712, PMID 35731991, PMID 37505794, PMID 11586105, PMID 12525516, PMID 14670747, PMID 15936157, PMID 16314615, PMID 16782910, PMID 16782911, PMID 17097834, PMID 17549014, PMID 17989384, PMID 18089866, PMID 18089867, PMID 18371182, PMID 18976072, PMID 19224764, PMID 19783377, PMID 19828373, PMID 19901104, PMID 20160062, PMID 20820870, PMID 20855843, PMID 21079154, PMID 21246521, PMID 21914791, PMID 22665535, PMID 22851558, PMID 23071237, PMID 23071247, PMID 23269986, PMID 24419119, PMID 27050206, PMID 27114593, PMID 27332902, PMID 29416652, PMID 30049811, PMID 30220622, PMID 30723079, PMID 31331918, PMID 32706640, PMID 34895479, PMID 36858722, PMID 37883739, PMID 39058968, PMID 39745682, PMID 40639904, PMID 9187443
P30CA043703 (4), P30CA016672 (2), 2004 (1), U01CA121947 (1), U10CA032102 (1), U10CA180821 (1), U10CA180886 (1)