23 completed, 17 unknown, 5 not yet recruiting, 3 active not recruiting. 37 Not applicable, 6 Phase 2, 3 Phase 3, 3 Phase 4, 2 Phase 1.
Follow PRF: new trials by email Literature Review of PRF trials Research Report on PRF
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison Between Greater Occipital Nerve Block and Pulsed Radiofrequency in the Management of Chronic Migraine Greater occiptal nerve block, Pulsed radiofrequency - Chronic Migraine, Headache | Not applicable | Not yet recruiting | Sohag University | 70 | 2026-05-01 | 2026-04-06 |
| The Effect of Platelet Rich Fibrin On Sensitivity and Periodontal Pockets Distal to Second Molar After Surgical Extraction of Impacted Third Molar Platelet rich fibrin - Third Molar Impaction, Surgical Extraction of Impacted Third Molars | Not applicable | Not yet recruiting | University of Health Sciences Lahore | 56 | 2026-02-01 | 2026-01-20 |
| Efficacy Of Platelet Rich Fibrin (PRF) In Neurosensory Disturbance Among Patients With Mandibular Body Fractures Platelets rich Fibrin - Neurosensory Disturbance, Mandibular Body Fractures | Not applicable | Not yet recruiting | University of Health Sciences Lahore | 40 | 2026-01-01 | 2026-01-06 |
| Clinical and Radiographic Evaluation of Indirect Pulp Capping Using Platelet Rich Fibrin Versus Mineral Trioxide Aggregate in Deep Carious Molars: a Randomized Controlled Trial MTA, PRF - Dental Caries, Pulp Caping | Phase 2 | Not yet recruiting | Cairo University | 50 | 2025-06-01 | 2025-03-21 |
| Esketamine Combined With PRF for Trigeminal Postherpetic Neuralgia esketamine group, control group - Postherpetic; Neuralgia, Trigeminal (Etiology) | Not applicable | Not yet recruiting | Beijing Tiantan Hospital | 174 | 2025-04-01 | 2025-04-09 |
| Evaluation of the Effect of Different Biomaterials on Palatal Wound Healing. Palatal wound will be covered with Ora-aid patch, Palatal wound will be covered with Composite stent, Palatal wound will be covered with PRF - Heal Wound, VAS Will be Used to Assess Pain Postoperative | Not applicable | Completed | Fatma saad saad mahmoud elsherbini | 40 | 2025-03-20 | 2025-07-18 |
| Effectiveness of High-Voltage PRF for Chronic Lumbosacral Radicular Pain Pulsed Radiofrequency, Post-operative Analgesia - Lumbosacral Radicular Pain, Chronic Radicular Back Pain | Not applicable | Completed | Hasanuddin University | 22 | 2025-02-07 | 2025-12-24 |
| Bone Marrow Aspirate Versus Platelet-Rich Fibrin for the Treatment of Chronic Plantar Fasciitis Bone Marrow Aspirate Injection, Platelet-Rich Fibrin Injection - Plantar Fasciitis | Not applicable | Recruiting | Federal University of São Paulo | 72 | 2025-02-01 | 2025-11-21 |
| SPG Pulsed Radiofrequency for Chronic Cluster Headache PRF, NB - Headache, Cluster | Not applicable | Recruiting | Beijing Tiantan Hospital | 108 | 2025-01-24 | 2025-01-27 |
| 3D Analysis of Soft Tissue Healing After Immediate Implant Placement Using PRF Vs HAM PRF, Human amniotic membrane, No grafting - Badly Broken Maxillary Premolars Indicated for Extraction, Badly Broken Down Vital Teeth | Not applicable | Active not recruiting | Ain Shams University | 36 | 2025-01-07 | 2025-02-19 |
| Neurorrhaphy Only vs Neurorrhaphy Plus PRF vs Neurorrhaphy Plus Nano-fat in Management of Traumatic Facial Nerve Injury Platelets Rich Fibrin, Nano-fat stem cells (NFSCs), Repair only - Facial Nerve Injuries, Facial Trauma | Not applicable | Active not recruiting | Assiut University | 21 | 2024-10-01 | 2025-05-18 |
| Outcome of NSRCT Versus VPT in Management of Teeth with Symptomatic Irreversible Pulpitis Associated with Apical Periodontitis root canal tretment, biodentin VPT, PRF - Endodontically Treated Teeth | Not applicable | Unknown | Minia University | 36 | 2024-05-01 | 2024-11-20 |
| The Assessment of Curcuma Longa Potentials for Soft and Hard Tissue Healing in Fresh PRF, Curcuma Longa gel, extraction socket - Tooth Extraction Status Nos, Tooth Fracture | Phase 1 | Completed | Rania Farouk Mohamed Abdulmaguid | 30 | 2024-05-01 | 2026-03-27 |
| Evaluation of Using Iliac Crest With and Without Platelet-Rich Fibrin in Repair of Congenital Alveolar Cleft alveolar bone grafting, alveolar bone grafting Plus Platelet rich fibrin - Alveolar Clefts, Alveolar Bone Grafting | Not applicable | Active not recruiting | Suez Canal University | 16 | 2024-04-27 | 2025-04-11 |
| Topical Application of PRF Before Radiation Therapy PRF, Natural Healing - PRF | Not applicable | Recruiting | University of Giessen | 34 | 2023-12-01 | 2025-04-11 |
| Treatment Of Shallow Periodontal Pockets Using PRF As an Adjunct To Scaling And Root Planing In Periodontitis Patients PRF - Periodontitis | Not applicable | Unknown | University of Baghdad | 12 | 2023-07-30 | 2023-06-06 |
| The Efficacy and Safety of Platelet-rich Fibrin and Platelet Rich Plasma in Female Pattern Hair Loss Patients Platelet rich plasma, Platelet rich fibrin - Female Pattern Hair Loss, Platelet-Rich Plasma | Not applicable | Unknown | Siriraj Hospital | 10 | 2023-05-30 | 2024-06-04 |
| Application of Platelet-Rich Fibrin on Diabetic Foot Wound PRF - Diabetic Foot | Not applicable | Unknown | Abant Izzet Baysal University | 14 | 2023-02-15 | 2023-02-01 |
| The Use of Platelet-rich-fibrin in Lower Third Molar Surgery. PRF - Facial Swelling, Tooth Position Anomalies | Not applicable | Completed | Amerigo Giudice | 31 | 2022-10-01 | 2023-12-11 |
| Pulsed Radiofrequency Treatment Of the Gasserian Ganglion for tRigeminal nEuralgia: a retroSpective Study PRF - Trigeminal Neuralgia (TN) | Completed | Ziekenhuis Oost-Limburg | 85 | 2022-04-17 | 2023-12-18 |
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Periodontitis (4) · Dental Caries (3) · Alveolar Bone Loss (1) · Bone Resorption (1) · Bursitis (1) · Chronic Pain (1) · Cicatrix (1) · Cluster Headache (1) · Dental Pulp Necrosis (1) · Diabetic Foot (1) · Facial Nerve Injuries (1) · Fasciitis, Plantar (1) · Furcation Defects (1) · Gingival Hyperplasia (1) · Gingival Recession (1)
Cairo University (5) · Assiut University (4) · Ain Shams University (3) · Beijing Tiantan Hospital (2) · University of Baghdad (2) · University of Health Sciences Lahore (2) · Abant Izzet Baysal University (1) · Ahmed adel shaaban (1) · Al-Azhar University (1) · Amerigo Giudice (1) · Attikon Hospital (1) · Dr. D. Y. Patil Dental College & Hospital (1) · Fatma saad saad mahmoud elsherbini (1) · Federal University of São Paulo (1) · Fujian Medical University (1)
Egypt (14) · China (4) · Pakistan (3) · Belgium (2) · Iran (2) · Brazil (1) · Bulgaria (1) · Canada (1) · Germany (1) · Greece (1) · India (1) · Indonesia (1) · Iraq (1) · Italy (1) · Netherlands (1)
Abdelrady S Ibrahim, M.D. (1) · Abeer H Mahran, professor (1) · Ahmad Reza Jodati, CTS (1) · Ahmed Y Gamal, PhD (1) · Aliaa E Ebrahim (1) · Azza Ezzelarab (1) · Deniz Cetiner, Prof. Dr. (1) · Doaa M. Selim, Specialist (1) · Dr Gulraiz Zulfiqar, FCPS(OMFS) (1) · Farhan A Rahman, MD (1) · Francesco Carli, Professor (1) · Jan Van Zundert (1)
PMID 20551021, PMID 23606475, PMID 23692143, PMID 24121608, PMID 24459346, PMID 25041873, PMID 25276813, PMID 25468584, PMID 26079800, PMID 26557476, PMID 29166306, PMID 33179073, PMID 33920204, PMID 34004239, PMID 34066483, PMID 34146510, PMID 34229752, PMID 34924312, PMID 36268950, PMID 37311285, PMID 37445386, PMID 38318237, PMID 38711308, PMID 38997108, PMID 40271482