9 completed. 9 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 9 | Completed 9 |
Follow pramlintide: new trials by email Literature Review of pramlintide trials Research Report on pramlintide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pramlintide (Symlin) for the Treatment of Hypoglycemia Following Gastric Bypass Surgery Pramlintide - Hypoglycemia, Evidence of Previous Gastric Surgery | Phase 4 | Completed | Joslin Diabetes Center | 22 | 2010-02-02 | 2023-06-29 |
| Use of Exenatide and Pramlintide to Decrease Post-prandial Hyperglycemia Pramlintide, Exenatide, Insulin - Type 1 Diabetes | Phase 4 | Completed | Albert Einstein College of Medicine | 37 | 2009-08-01 | 2018-04-12 |
| The Effect of Byetta and Symlin on Post-meal Meal Blood Sugar Levels in Children With Type 2 Diabetes Byetta (exenatide), Symlin (pramlintide) - Type 2 Diabetes | Phase 4 | Completed | Baylor College of Medicine | 16 | 2009-07-01 | 2017-04-24 |
| Demonstrate the Effects of Pramlintide on Weight Reduction in Schizophrenia Pramlintide, Placebo - Schizophrenia, Schizoaffective Disorder | Phase 4 | Completed | University of Texas Southwestern Medical Center | 33 | 2007-11-01 | 2018-11-16 |
| A Pilot Study of Continuous Subcutaneous Pramlintide Infusion Therapy in Patients With Type 1 Diabetes Continuous Pramlintide infusion - IDDM | Phase 4 | Completed | University Diabetes & Endocrine Consultants | 12 | 2007-07-01 | 2013-01-16 |
| A Study to Characterize Regimens of Basal Insulin Intensified With Either Symlin® or Rapid Acting Insulin in Patients With Type 2 Diabetes pramlintide acetate (Symlin), rapid acting insulin (Humalog® [insulin lispro], Novolog® [insulin aspart], or Apidra® [insulin glulisine]), basal insulin (Lantus® [insulin glargine], or Levemir® [insulin detemir]) - Type 2 Diabetes Mellitus | Phase 4 | Completed | AstraZeneca | 112 | 2007-05-01 | 2015-04-14 |
| Post-meal Insulin Dosing With Adjuvant Pre-meal Pramlintide in Children With Type 1 Diabetes Mellitus Insulin, Pramlintide + Insulin - Type 1 Diabetes Mellitus | Phase 4 | Completed | Montefiore Medical Center | 8 | 2007-02-01 | 2018-07-10 |
| Continuous Subcutaneous Infusion of Pramlintide and Insulin Pramlintide - Type 1 Diabetes | Phase 4 | Completed | Baylor College of Medicine | 13 | 2006-01-01 | 2016-07-14 |
| A Study Evaluating the Efficacy and Safety of Adding Symlin® to Lantus® (Insulin Glargine) in Subjects With Type 2 Diabetes pramlintide acetate - Type 2 Diabetes Mellitus | Phase 4 | Completed | AstraZeneca | 200 | 2005-10-01 | 2015-03-31 |
Diabetes Mellitus (5) · Diabetes Mellitus, Type 1 (4) · Diabetes Mellitus, Type 2 (3) · Hypoglycemia (2) · Insulin Resistance (2) · Hyperglycemia (1) · Metabolic Syndrome (1) · Obesity (1) · Psychotic Disorders (1) · Schizophrenia (1) · Weight Gain (1)
AstraZeneca (2) · Baylor College of Medicine (2) · Albert Einstein College of Medicine (1) · Joslin Diabetes Center (1) · Montefiore Medical Center (1) · University Diabetes & Endocrine Consultants (1) · University of Texas Southwestern Medical Center (1)
United States (9)
Lisa Porter, MD (2) · Rubina A Heptulla, MD (2) · Carol A Tamminga, MD (1) · David M Huffman, MD (1) · Mary E. Patti, MD (1) · Rubina Heptulla, MD (1)
PMID 15793249, PMID 17698615, PMID 18031595, PMID 19049375, PMID 19190104, PMID 19546056, PMID 20199136
K23DK075931 (1), R01DK077166 (1)