10 completed. 10 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 10 |
| Phase 1 | 1 | Completed 1 |
Follow potassium nitrate: new trials by email Literature Review of potassium nitrate trials Research Report on potassium nitrate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Characterize the Efficacy of a Dual Active Dentifrice for the Relief of Dentin Hypersensitivity Potassium Nitrate, Stannous Fluoride - Dentin Hypersensitivity, Dentin Sensitivity | Phase 2 | Completed | GlaxoSmithKline | 123 | 2019-05-13 | 2020-09-11 |
| The Use of Inorganic Nitrate for the Prevention of Contrast-induced Nephropathy Potassium Nitrate, Potassium Chloride - Contrast-induced Nephropathy, Acute Kidney Injury | Phase 2 | Completed | Barts & The London NHS Trust | 640 | 2018-11-29 | 2022-12-16 |
| Targeting Pulsatile Load to Increase Exercise Capacity and Quality of Life After Aortic Valve Replacement for Severe Aortic Stenosis (PULSE AS) Potassium Nitrate, Potassium Chloride - Aortic Valve Stenosis | Phase 2 | Completed | University of Pennsylvania | 5 | 2018-05-01 | 2020-06-17 |
| Inorganic NItrate and EXercise Performance in Heart Failure (iNIX-HF): Dose Response KNO3, potassium nitrate - Heart Failure | Phase 1 / Phase 2 | Completed | Washington University School of Medicine | 42 | 2017-10-31 | 2025-05-20 |
| Different Concentrations of Potassium Nitrate in In-office Tooth Bleaching Sensitivity 3% potassium nitrate and 0.25% sodium fluoride, 5% potassium nitrate and 2% sodium fluoride - Tooth Sensitivity | Phase 2 | Completed | Universidade Federal do Amazonas | 56 | 2016-12-21 | 2017-10-27 |
| Effect of KNO3 Compared to KCl on Oxygen UpTake in Heart Failure With Preserved Ejection Fraction (KNO3CK OUT HFPEF) Potassium Nitrate (KNO3), Potassium Chloride (KCl) - Heart Failure | Phase 2 | Completed | University of Pennsylvania | 84 | 2016-08-01 | 2023-12-18 |
| Clinical Efficacy in Relieving Dentin Hypersensitivity of Nanohydroxyapatite-Containing Toothpastes and Cream Control toothpaste containing Novamin® technology, Control toothpaste containing 1500 ppm fluoride as MFP, Test toothpaste with nano-HAP (high concentration) - Dentin Sensitivity | Phase 2 | Completed | The University of Texas Health Science Center at San Antonio | 203 | 2015-05-01 | 2018-11-16 |
| Pharmacokinetics, Pharmacodynamics, and Impact of Inorganic Nitrate on Exercise in HFpEF KNO3, KCl - Heart Failure, Diastolic Heart Failure | Phase 2 | Completed | University of Pennsylvania | 12 | 2015-01-01 | 2017-10-03 |
| Clinical Study Investigating the Efficacy of a Mouthwash in Providing Long Term Relief From Dentinal Hypersensitivity Potassium nitrate and sodium fluoride, Standard fluoride dentifrice - Dentin Sensitivity | Phase 2 | Completed | GlaxoSmithKline | 191 | 2014-09-02 | 2018-08-27 |
| Efficacy of Potassium Nitrate Solution in Reducing Dentinal Hypersensitivity 5% Potassium nitrate, 2.5% Potassium nitrate, Sterile water - Dentine Hypersensitivity | Phase 2 | Completed | GlaxoSmithKline | 32 | 2009-09-01 | 2015-01-26 |
Dentin Sensitivity (5) · Heart Failure (3) · Acute Coronary Syndrome (1) · Acute Kidney Injury (1) · Aortic Valve Stenosis (1) · Heart Failure, Diastolic (1)
GlaxoSmithKline (3) · University of Pennsylvania (3) · Barts & The London NHS Trust (1) · The University of Texas Health Science Center at San Antonio (1) · Universidade Federal do Amazonas (1) · Washington University School of Medicine (1)
United States (7) · Canada (1) · United Kingdom (1)
Amrita Ahluwalia, PhD (1) · Andrew R Coggan, PhD (1) · Bennett T Amaechi, BDS, MS, PhD (1) · Julio A Chirinos, MD (1) · Julio A Chirinos, MD, PhD (1) · Julio Chirinos, MD (1) · Leandro M Martins, doctorate (1) · Linda R Peterson, MD (1) · Payman Zamani, MD (1) · Sanjiv Shah, MD (1) · Sujith Kuruvilla, MD (1)
PMID 27927683, PMID 30803493, PMID 33764198, PMID 38513060, PMID 39693096
2016 (1)