9 completed, 3 terminated, 1 recruiting. 9 Phase 2, 6 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 6, Terminated 2, Recruiting 1 |
| Phase 1 | 6 | Completed 4, Terminated 2 |
| Phase 3 | 1 | Completed 1 |
Follow Podophyllotoxin: new trials by email Literature Review of Podophyllotoxin trials Research Report on Podophyllotoxin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Atezolizumab Plus Etoposide and Platinum in Small Cell Bladder Cancer Atezolizumab, Carboplatin, Cisplatin - Small Cell Neuroendocrine Carcinoma of Bladder, Bladder Cancer | Phase 2 | Recruiting | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 63 | 2022-06-27 | 2026-06-25 |
| Chemotherapy Based on PET Scan in Treating Patients With Stage I or Stage II Hodgkin Lymphoma Doxorubicin, Bleomycin, Vinblastine - Lymphoma | Phase 2 | Terminated | ECOG-ACRIN Cancer Research Group | 6 | 2013-05-24 | 2023-06-29 |
| Cisplatin and Etoposide With or Without Veliparib in Treating Patients With Extensive Stage Small Cell Lung Cancer Cisplatin, Etoposide, Veliparib - Extensive Stage Small Cell Lung Carcinoma, Large Cell Lung Carcinoma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 156 | 2012-09-28 | 2026-06-24 |
| Phase I Combination of Midostaurin, Bortezomib, and Chemo in Relapsed/Refractory Acute Myeloid Leukemia midostaurin, Bortezomib, mitoxantrone hydrochloride - Acute Myeloid Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following | Phase 1 | Completed | Alison Walker | 34 | 2010-08-01 | 2016-07-06 |
| Bortezomib, Mitoxantrone, Etoposide, and Cytarabine in Relapsed or Refractory Acute Myeloid Leukemia bortezomib, mitoxantrone hydrochloride, etoposide - Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Phase 1 | Completed | Case Comprehensive Cancer Center | 3 | 2010-07-01 | 2015-08-13 |
| Proton Beam Radiation Therapy and Chemotherapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Can Be Removed By Surgery proton beam radiation therapy, cisplatin, etoposide - Stage IIIA Non-small Cell Lung Cancer | Phase 1 / Phase 2 | Completed | Abramson Cancer Center at Penn Medicine | 34 | 2010-01-01 | 2021-05-17 |
| Carboplatin and Etoposide Plus LBH589 for Small Cell Lung Cancer LBH589 and carboplatin with etoposide - Small Cell Lung Cancer | Phase 1 | Terminated | Ahmad Tarhini | 7 | 2009-09-01 | 2017-06-22 |
| Busulfan, Etoposide, and Intensity-Modulated Radiation Therapy Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Myeloid Cancer busulfan, etoposide, intensity-modulated radiation therapy - Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Phase 1 / Phase 2 | Terminated | City of Hope Medical Center | 25 | 2007-06-11 | 2023-11-30 |
| Doxorubicin Hydrochloride Liposome and Rituximab With Combination Chemotherapy in Treating Patients With Newly Diagnosed Burkitt's Lymphoma or Burkitt-Like Lymphoma Regimen A, Regimen B - Lymphoma | Phase 2 | Completed | Northwestern University | 25 | 2007-02-06 | 2019-10-15 |
| Rituximab and Combination Chemotherapy in Treating Patients With Stage II, Stage III, or Stage IV Diffuse Large B-Cell Non-Hodgkin's Lymphoma filgrastim, rituximab, carboplatin - Lymphoma | Phase 2 | Completed | Eastern Cooperative Oncology Group | 100 | 2006-09-26 | 2023-06-29 |
| Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Extensive-Stage Small Cell Lung Cancer G-CSF, Cisplatin, Etoposide - Extensive Stage Small Cell Lung Cancer | Phase 2 | Completed | Eastern Cooperative Oncology Group | 140 | 2004-07-14 | 2023-07-05 |
| Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma filgrastim, carboplatin, cyclophosphamide - Brain Tumor, Central Nervous System Tumor | Phase 2 | Completed | Children's Oncology Group | 378 | 2003-08-01 | 2019-08-07 |
| Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Hodgkin's Lymphoma Doxorubicin, Bleomycin, Vinblastine - Lymphoma | Phase 3 | Completed | Eastern Cooperative Oncology Group | 854 | 1999-06-17 | 2023-06-29 |
Lymphoma (4) · Congenital Abnormalities (3) · Leukemia, Myeloid, Acute (3) · Carcinoma, Non-Small-Cell Lung (2) · Hodgkin Disease (2) · Small Cell Lung Carcinoma (2) · Anemia, Refractory, with Excess of Blasts (1) · Blast Crisis (1) · Brain Neoplasms (1) · Burkitt Lymphoma (1) · Carcinoma, Neuroendocrine (1) · Carcinoma, Small Cell (1) · Central Nervous System Neoplasms (1) · Leukemia, Erythroblastic, Acute (1) · Leukemia, Megakaryoblastic, Acute (1)
Eastern Cooperative Oncology Group (3) · Abramson Cancer Center at Penn Medicine (1) · Ahmad Tarhini (1) · Alison Walker (1) · Case Comprehensive Cancer Center (1) · Children's Oncology Group (1) · City of Hope Medical Center (1) · ECOG-ACRIN Cancer Research Group (1) · National Cancer Institute (NCI) (1) · Northwestern University (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1)
United States (13) · Canada (2) · Australia (1) · Netherlands (1) · New Zealand (1) · South Africa (1) · Switzerland (1)
Ahmad A Tarhini, MD (1) · Alison Walker, MD (1) · Anjali Advani (1) · Anthony Stein (1) · Jacob Shabason, MD (1) · Jean Hoffman-Censits, MD (1) · Joseph Aisner, MD (1) · Leo Gordon, MD (1) · Lode J. Swinnen, MD (1) · Ranjana Advani, MD (1) · Sandra J. Horning, MD (1) · Taofeek Owonikoko (1) · Thomas E. Merchant, DO, PhD (1)
PMID 19767508, PMID 23182987, PMID 23356491, PMID 23386127, PMID 24146219, PMID 25897153, PMID 26784138, PMID 30523756, PMID 32860331, PMID 37201756
U10CA021115 (4), P30CA060553 (1), U01CA079778 (1), U01CA080098 (1), U10CA180820 (1), U24CA196172 (1)