4 completed, 2 terminated. 6 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 4, Terminated 2 |
| Phase 2 | 3 | Completed 2, Terminated 1 |
Follow Podophyllotoxin: new trials by email Literature Review of Podophyllotoxin trials Research Report on Podophyllotoxin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cisplatin and Etoposide With or Without Veliparib in Treating Patients With Extensive Stage Small Cell Lung Cancer Cisplatin, Etoposide, Veliparib - Extensive Stage Small Cell Lung Carcinoma, Large Cell Lung Carcinoma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 156 | 2012-09-28 | 2026-06-24 |
| Phase I Combination of Midostaurin, Bortezomib, and Chemo in Relapsed/Refractory Acute Myeloid Leukemia midostaurin, Bortezomib, mitoxantrone hydrochloride - Acute Myeloid Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following | Phase 1 | Completed | Alison Walker | 34 | 2010-08-01 | 2016-07-06 |
| Bortezomib, Mitoxantrone, Etoposide, and Cytarabine in Relapsed or Refractory Acute Myeloid Leukemia bortezomib, mitoxantrone hydrochloride, etoposide - Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Phase 1 | Completed | Case Comprehensive Cancer Center | 3 | 2010-07-01 | 2015-08-13 |
| Proton Beam Radiation Therapy and Chemotherapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Can Be Removed By Surgery proton beam radiation therapy, cisplatin, etoposide - Stage IIIA Non-small Cell Lung Cancer | Phase 1 / Phase 2 | Completed | Abramson Cancer Center at Penn Medicine | 34 | 2010-01-01 | 2021-05-17 |
| Carboplatin and Etoposide Plus LBH589 for Small Cell Lung Cancer LBH589 and carboplatin with etoposide - Small Cell Lung Cancer | Phase 1 | Terminated | Ahmad Tarhini | 7 | 2009-09-01 | 2017-06-22 |
| Busulfan, Etoposide, and Intensity-Modulated Radiation Therapy Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Myeloid Cancer busulfan, etoposide, intensity-modulated radiation therapy - Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Phase 1 / Phase 2 | Terminated | City of Hope Medical Center | 25 | 2007-06-11 | 2023-11-30 |
Congenital Abnormalities (3) · Leukemia, Myeloid, Acute (3) · Carcinoma, Non-Small-Cell Lung (2) · Small Cell Lung Carcinoma (2) · Anemia, Refractory, with Excess of Blasts (1) · Blast Crisis (1) · Carcinoma, Neuroendocrine (1) · Carcinoma, Small Cell (1) · Leukemia, Erythroblastic, Acute (1) · Leukemia, Megakaryoblastic, Acute (1) · Leukemia, Monocytic, Acute (1) · Leukemia, Myelomonocytic, Acute (1) · Myelodysplastic Syndromes (1)
Abramson Cancer Center at Penn Medicine (1) · Ahmad Tarhini (1) · Alison Walker (1) · Case Comprehensive Cancer Center (1) · City of Hope Medical Center (1) · National Cancer Institute (NCI) (1)
United States (6)
Ahmad A Tarhini, MD (1) · Alison Walker, MD (1) · Anjali Advani (1) · Anthony Stein (1) · Jacob Shabason, MD (1) · Taofeek Owonikoko (1)
PMID 26784138, PMID 30523756, PMID 32860331, PMID 37201756
U10CA021115 (1), U10CA180820 (1), U24CA196172 (1)