6 completed, 2 terminated, 1 unknown, 1 withdrawn. 10 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 10 | Completed 6, Terminated 2, Unknown 1, Withdrawn 1 |
Follow Phenprocoumon: new trials by email Literature Review of Phenprocoumon trials Research Report on Phenprocoumon
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical Therapy CE-mark approved LAA closure devices, Acetylsalicylic acid, Clopidogrel - Atrial Fibrillation | Phase 4 | Completed | Charite University, Berlin, Germany | 912 | 2018-02-28 | 2025-12-12 |
| COMBO-Stent in Patients on Chronic Anticoagulant Therapy (COSTA) COSTA-Bleed and COSTA-Outcome Trials COMBO-Stent, Clopidogrel, Vitamin K Antagonist, Rivaroxaban, Dabigatran, Any drug eluting stent oder bare metal sent - Stable Angina, Unstable Angina | Phase 4 | Withdrawn | IHF GmbH - Institut für Herzinfarktforschung | 2016-04-01 | 2017-02-20 | |
| Left Atrial Thrombus Reduction - Effect of Dabigatran Versus Phenprocoumon Dabigatranetexilate, Phenprocoumon - Atrial Fibrillation, Left Atrial Thrombosis | Phase 4 | Unknown | University of Ulm | 40 | 2015-10-01 | 2015-11-13 |
| Apixaban During Atrial Fibrillation Catheter Ablation: Comparison to Vitamin K Antagonist Therapy Vitamin K antagonist, Apixaban - Atrial Fibrillation | Phase 4 | Completed | Atrial Fibrillation Network | 676 | 2014-12-01 | 2017-10-20 |
| Rivaroxaban Compared to Vitamin K Antagonist Upon Development of Cardiovascular Calcification Rivaroxaban or Marcumar - Atrial Fibrillation or Pulmonary Embolism, Need of Long Term Oral Anticoagulation Therapy (OAT) | Phase 4 | Completed | RWTH Aachen University | 192 | 2013-07-01 | 2020-10-22 |
| Antithrombotic Triple Therapy in Humans Dabigatran, Ticagrelor, ASA, Rivaroxaban, Ticagrelor, ASA, Phenprocoumon, Ticagrelor, ASA - Atrial Fibrillation, Acute Coronary Syndrome | Phase 4 | Completed | Medical University of Vienna | 60 | 2012-10-01 | 2014-03-06 |
| Impact of Dabigatran and Phenprocoumon on Clopidogrel Mediated ADP Induced Platelet Aggregation in Patients With Atrial Fibrillation Dabigatran, Phenprocoumon - Coronary Heart Disease, Atrial Fibrillation | Phase 4 | Terminated | Deutsches Herzzentrum Muenchen | 46 | 2011-05-01 | 2015-02-05 |
| Impact of Dabigatran and Phenprocoumon on ADP Induced Platelet Aggregation in Patients With Atrial Fibrillation Dabigatran, Phenprocoumon - Atrial Fibrillation | Phase 4 | Completed | Deutsches Herzzentrum Muenchen | 70 | 2011-04-01 | 2013-07-02 |
| Study to Find Out the Appropriate Initial Dose of the Anticoagulant Drug Phenprocoumon Algorithm for phenprocoumon, algorithm for phenprocoumon, Phenprocoumon - Pulmonary Embolism, Atrial Fibrillation | Phase 4 | Completed | Cantonal Hospital of St. Gallen | 302 | 2007-01-01 | 2012-04-02 |
| Very Low Dose Oral Anticoagulation and Thromboembolic and Bleeding Complications phenprocoumon - Mechanical Heart Valve Recipients | Phase 4 | Terminated | Heart and Diabetes Center North-Rhine Westfalia | 1571 | 2006-01-01 | 2013-12-11 |
Atrial Fibrillation (8) · Acute Coronary Syndrome (2) · Coronary Disease (2) · Pulmonary Embolism (2) · Angina, Stable (1) · Angina, Unstable (1) · Atherosclerosis (1) · Hemorrhage (1) · Non-ST Elevated Myocardial Infarction (1) · ST Elevation Myocardial Infarction (1) · Stroke (1) · Thromboembolism (1)
Deutsches Herzzentrum Muenchen (2) · Atrial Fibrillation Network (1) · Cantonal Hospital of St. Gallen (1) · Charite University, Berlin, Germany (1) · Heart and Diabetes Center North-Rhine Westfalia (1) · IHF GmbH - Institut für Herzinfarktforschung (1) · Medical University of Vienna (1) · RWTH Aachen University (1) · University of Ulm (1)
Germany (8) · Austria (2) · Belgium (1) · Denmark (1) · Italy (1) · Netherlands (1) · Spain (1) · Switzerland (1) · United Kingdom (1) · United States (1)
Julinda Mehilli, MD (2) · Heinrich Koertke, MD (1) · Ibrahim Akin (1) · Michael Wolzt, Prof. MD (1) · Paulus Kirchhof, Professor (1) · Peter Bernhardt, MD (1) · Samuel Henz, MD MPH (1) · Tommasso Gori (1) · Ulf Landmesser, MD (1) · Wolfgang Korte, MD (1)
PMID 23299853, PMID 25211369, PMID 32725107, PMID 35135308, PMID 37897713, PMID 40946883, PMID 41849741, PMID 42459774
2014 (1)