3 active not recruiting, 2 completed, 2 not yet recruiting, 2 recruiting. 11 Phase 2, 10 Phase 1, 2 Phase 3.
Follow Phage Therapy: new trials by email Literature Review of Phage Therapy trials Research Report on Phage Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| "Debridement PhagE AnTibiotics for PJI" The investigational product specifically targeting P. aeruginosa (DP-QB-PSA-005) and that targeting S. aureus (DP-QB-STA-005), each formed of a mixture of 5 bacteriophages. - Periprosthetic Infection | Phase 2 / Phase 3 | Not yet recruiting | Ottawa Hospital Research Institute | 10 | 2026-07-02 | 2026-07-13 |
| Phage Therapy for Recurrent UTIs in Kidney Transplant Recipients phage therapy, control - Urinary Tract Infection, Recurrent | Phase 1 / Phase 2 | Recruiting | University of California, San Diego | 32 | 2025-06-15 | 2025-08-14 |
| Phage Therapy for the Treatment of a Chronic Enterococcus Faecium Periprosthetic Joint Infection Phage Therapy - Periprosthetic Joint Infection | Phase 1 / Phase 2 | Not yet recruiting | Orthopaedic Innovation Centre | 1 | 2025-05-01 | 2025-04-24 |
| Bacteriophage Therapy for Morganella Morganii Prosthetic Joint Infection phage therapy - Prosthetic Joint Infections of Hip | Phase 1 / Phase 2 | Active not recruiting | University of Calgary | 1 | 2025-03-26 | 2025-06-12 |
| Bacteriophage Therapy in Spinal Cord Injury Patients With Bacteriuria Phage Therapy, Placebo - Bacteriuria, Spinal Cord Injuries | Phase 1 | Recruiting | Barbara Trautner | 30 | 2025-02-03 | 2026-05-05 |
| Bacteriophage Therapy for Methicillin-Sensitive Staphylococcus Aureus Prosthetic Joint Infection Phage therapy - Prosthetic Joint Infections of Hip, Staphylococcus Aureus Infection | Phase 1 / Phase 2 | Active not recruiting | University of Calgary | 1 | 2024-11-20 | 2025-06-11 |
| Phage Therapy for the Treatment of Urinary Tract Infection Phage Therapy - Recurrent Urinary Tract Infection | Phase 1 / Phase 2 | Unknown | Unity Health Toronto | 1 | 2023-05-01 | 2024-03-26 |
| Bacteriophage Therapy in Patients With Prosthetic Joint Infections Phage Therapy, Two-Stage Exchange Arthroplasty - Prosthetic Joint Infection | Phase 1 / Phase 2 | Withdrawn | Adaptive Phage Therapeutics, Inc. | 2022-10-01 | 2022-04-04 | |
| Bacteriophage Therapy in First Time Chronic Prosthetic Joint Infections Phage Therapy - Prosthetic Joint Infection, Bacterial Infections | Phase 1 / Phase 2 | Withdrawn | Adaptive Phage Therapeutics, Inc. | 2022-09-01 | 2024-02-22 | |
| Bacteriophage Therapy in Patients With Diabetic Foot Osteomyelitis Bacteriophage Therapy, Placebo - Osteomyelitis, Diabetic Foot Osteomyelitis | Phase 2 | Terminated | Adaptive Phage Therapeutics, Inc. | 41 | 2021-11-24 | 2025-08-19 |
| CYstic Fibrosis bacterioPHage Study at Yale (CYPHY) Standard Dose YPT-01, Placebo - Cystic Fibrosis | Phase 1 / Phase 2 | Completed | Yale University | 8 | 2021-03-29 | 2023-11-18 |
| Bacteriophage Therapy in Patients With Urinary Tract Infections Bacteriophage Therapy - Urinary Tract Infection Bacterial | Phase 1 / Phase 2 | Terminated | Adaptive Phage Therapeutics, Inc. | 1 | 2020-12-09 | 2023-03-03 |
| Bacteriophage Therapy in Tonsillitis Nebulizer inhalation irrigation of the mucous membranes of the tonsils with a bacteriophage. - Acute Tonsillitis | Phase 3 | Active not recruiting | Tashkent State Medical University (Tashkent Pediatric Medical Institute), Uzbekistan | 128 | 2020-10-02 | 2025-05-21 |
| Bacteriophage Therapy of Difficult-to-treat Infections Bacteriophage therapy - Bacterial Infections | Completed | Queen Astrid Military Hospital | 100 | 2008-01-01 | 2022-08-12 | |
| Personalized Phage Treatment in Covid-19 Patients With Bacterial Co-Infections Microbials for Pneumonia or Bacteremia/Septicemia Phage Therapy - Covid19, Bacteremia | No longer available | Adaptive Phage Therapeutics, Inc. | 2021-12-21 |
Urinary Tract Infections (3) · Bacterial Infections (2) · Pseudomonas Infections (2) · Staphylococcal Infections (2) · Bacteremia (1) · Bacteriuria (1) · COVID-19 (1) · Cystic Fibrosis (1) · Diabetes Mellitus (1) · Escherichia coli Infections (1) · Infections (1) · Osteomyelitis (1) · Sepsis (1) · Spinal Cord Injuries (1) · Urinary Bladder, Neurogenic (1)
Adaptive Phage Therapeutics, Inc. (5) · University of Calgary (2) · Barbara Trautner (1) · Orthopaedic Innovation Centre (1) · Ottawa Hospital Research Institute (1) · Queen Astrid Military Hospital (1) · Tashkent State Medical University (Tashkent Pediatric Medical Institute), Uzbekistan (1) · Unity Health Toronto (1) · University of California, San Diego (1) · Yale University (1)
United States (6) · Canada (5) · Uzbekistan (1)
Robert J Hopkins, MD (2) · Barbara W Trautner, MD, PhD (1) · Benjamin Chan, PhD (1) · David Hedden, MD (1) · Gregory German, MD PhD FRCPC (1) · Hesham Abdelbary, MD MSc FRCSC (1) · Jonathan Koff, MD (1) · Nitsan Halevy, MD (1) · Robert Hopkins, MD (1) · Sarah Djebara, MD (1) · Shokhida T. Turdieva, MD (1)