9 completed, 3 unknown, 2 terminated, 2 withdrawn. 16 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 16 | Completed 9, Unknown 3, Terminated 2, Withdrawn 2 |
| Phase 3 | 2 | Unknown 2 |
| Phase 1 | 1 | Terminated 1 |
Follow Petrolatum: new trials by email Literature Review of Petrolatum trials Research Report on Petrolatum
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Immunotherapy After Transplantation for Skin Cancer Prevention in Organ Transplant Recipients Calcipotriol Only Product in Cutaneous Dose Form, Vaseline, Topical 5FU - Immunotherapy, Cutaneous Squamous Cell Carcinoma | Phase 2 | Withdrawn | Massachusetts General Hospital | 2026-01-01 | 2025-05-07 | |
| Immunotherapy Before Transplantation for Skin Cancer Prevention in Organ Transplant Recipients Calcipotriol Only Product in Cutaneous Dose Form, Vaseline, Topical 5FU - Cutaneous Squamous Cell Carcinoma, Actinic Keratoses | Phase 2 | Withdrawn | Massachusetts General Hospital | 2026-01-01 | 2025-05-07 | |
| Dermaprazole Cream for Radiation Dermatitis in Head and Neck Cancer Dermaprazole, Aquaphor - Cancer of the Head and Neck | Phase 2 | Completed | The University of Texas Health Science Center at San Antonio | 6 | 2022-06-15 | 2025-08-06 |
| Efficacy of Tazarotene in Treatment of Verruca Plana Tazarotene 0.1% Gel,Top, Imiquimod, Fluorouracil Cream - Warts Flat | Phase 2 | Unknown | Zagazig University | 80 | 2022-04-15 | 2022-05-16 |
| Photoallergic Potential of 6% Bemotrizinol 6% Bemotrizinol in sunscreen formulation, 6% Bemotrizinol in petrolatum, Vehicle - Photoallergic Response | Phase 2 | Completed | dsm-firmenich Switzerland AG | 50 | 2022-03-07 | 2022-08-26 |
| Phototoxicity Potential of 6% Bemotrizinol Sunscreen oil with 6% Bemotrizinol, Sunscreen oil vehicle, Dispersion of 6% BEMT in petrolatum - Phototoxic Response | Phase 2 | Completed | dsm-firmenich Switzerland AG | 34 | 2022-02-28 | 2022-08-26 |
| Dermal Irritation, Sensitization and Cumulative Irritation Potential of 6% Bemotrizinol 6% Bemotrizinol (BEMT) in a basic sunscreen oil formulation, 6% Bemotrizinol (BEMT) dispersion in petrolatum, Sunscreen oil vehicle with 10% ethanol as penetration enhancer without BEMT - Sunburn | Phase 2 | Completed | dsm-firmenich Switzerland AG | 224 | 2022-02-23 | 2022-08-26 |
| Turmeric Based Therapy in the Treatment of Psoriasis: A Clinical Trial Turmeric Extract, Turmeric Extract in Olive oil, Petrolatum - Psoriasis | Phase 2 / Phase 3 | Unknown | Zagazig University | 50 | 2019-09-01 | 2019-08-28 |
| Sexual Penetration Pain in Postmenopausal Women: A Topical Botanical Drug Treatment 5% sinecatechins ointment, Placebo, 10% sinecatechins ointment - Sexual Pain Disorders, Postmenopausal Symptoms | Phase 2 | Terminated | GTO Pharmaceutical, LLC | 32 | 2018-08-30 | 2022-07-27 |
| Treatment of Plantar Keratosis With Medicinal Plant in Diabetic Patients Medicinal Plant, Salicylate, Vaseline - Keratosis Plantaris | Phase 2 | Completed | Universidade do Vale do Sapucai | 90 | 2017-06-01 | 2020-11-05 |
| Mupirocin to Reduce Staphylococcus Aureus Colonization in Infants Hospitalized in a NICU Mupirocin Topical Ointment, Petroleum Jelly - Staphylococcus | Phase 2 | Completed | Crouse Hospital | 216 | 2016-10-01 | 2020-12-21 |
| Diltiazem Gel Versus Nitroglycerin Ointment in Healing Process of Scleroderma Digital Ulcers Diltiazem Gel 2%, Nitroglycerin Ointment 2%, Vaseline - Digital Ulcer of Scleroderma | Phase 2 | Completed | Mohammad Ali Nazarinia | 90 | 2016-06-01 | 2017-03-06 |
| Topical Use of Difinsa53™ to Prevent Radiation Dermatitis Difinsa53, Aquaphor - Radiodermatitis | Phase 1 / Phase 2 | Terminated | ProTechSure Scientific, Inc. | 13 | 2015-08-01 | 2017-10-06 |
| Topical 2% Lidocaine for the Treatment of Symptomatic Hemorrhoids 2% lidocaine, placebo - Hemorrhoids | Phase 2 / Phase 3 | Unknown | University Hospital Dubrava | 138 | 2013-10-01 | 2013-10-14 |
| Sunitinib or Cediranib for Alveolar Soft Part Sarcoma Cediranib, Sunitinib, Prochlorperazine - Sarcoma, Alveolar Soft Part | Phase 2 | Completed | National Cancer Institute (NCI) | 34 | 2011-07-18 | 2026-02-02 |
| The Efficacy and Tolerability of Oleogel-S-10 in Patients With Actinic Keratoses Oleogel-S10 100 mg/g, Placebo (petroleum jelly) - Actinic Keratoses | Phase 2 | Completed | Birken AG | 165 | 2008-10-01 | 2015-09-14 |
Keratosis, Actinic (3) · Carcinoma, Squamous Cell (2) · Skin Neoplasms (2) · Breast Neoplasms (1) · Callosities (1) · Dermatitis (1) · Diabetes Mellitus (1) · Dyspareunia (1) · Head and Neck Neoplasms (1) · Hemorrhoids (1) · Keratosis (1) · Psoriasis (1) · Radiodermatitis (1) · Sarcoma, Alveolar Soft Part (1) · Scleroderma, Diffuse (1)
dsm-firmenich Switzerland AG (3) · Massachusetts General Hospital (2) · Zagazig University (2) · Birken AG (1) · Crouse Hospital (1) · GTO Pharmaceutical, LLC (1) · Mohammad Ali Nazarinia (1) · National Cancer Institute (NCI) (1) · ProTechSure Scientific, Inc. (1) · The University of Texas Health Science Center at San Antonio (1) · Universidade do Vale do Sapucai (1) · University Hospital Dubrava (1)
United States (10) · Brazil (1) · Croatia (1) · Egypt (1) · Germany (1) · Greece (1) · Iran (1)
Gladys Osis, MT (2) · Rolf Schutz, PhD (2) · Shadmehr Demehri, MD/PHD (2) · Alice P Chen, M.D. (1) · Claus Garbe, Prof. Dr. (1) · Hagar Nofal (1) · Joshua Petit, MD (1) · Lila Nachtigall, M.D. (1) · Mario Kopljar, MD, PhD (1) · Melissa U Nelson, MD (1) · Mohammad Ali Nazarinia, M.D. (1) · Samantha Poweski (1) · Shraddha Dalwadi, MD (1) · Tihomir Kekez (1)
PMID 11934971, PMID 22934545, PMID 23402088, PMID 23494072, PMID 23554239, PMID 24054756, PMID 25124939, PMID 26054651, PMID 34023342, PMID 36302173