10 completed, 2 terminated, 1 withdrawn. 13 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 13 | Completed 10, Terminated 2, Withdrawn 1 |
| Phase 1 | 2 | Completed 2 |
Follow paclitaxel poliglumex: new trials by email Literature Review of paclitaxel poliglumex trials Research Report on paclitaxel poliglumex
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PPX and Concurrent Radiation for Newly Diagnosed Glioblastoma Without MGMT Methylation PPX (CT2103), Temozolomide - Glioblastoma Multiforme | Phase 2 | Completed | Brown University | 63 | 2011-09-01 | 2020-02-17 |
| Neoadjuvant Doxorubicin, Polyglutamate Paclitaxel, Capecitabine and Metronomic Chemotherapy in Breast Cancer doxorubicin, paclitaxel poliglumex, capecitabine, cyclophosphamide, methotrexate - Breast Cancer | Phase 2 | Withdrawn | University of Southern California | 2009-02-01 | 2017-05-02 | |
| A Phase I/II Study of Radiation Therapy, Paclitaxel Poliglumex and Cetuximab in Advanced Head and Neck Cancer paclitaxel poliglumex, cetuximab, radiation therapy (IMRT or 3D-CRT) - Carcinoma, Squamous Cell | Phase 1 / Phase 2 | Completed | State University of New York - Upstate Medical University | 53 | 2008-03-01 | 2021-11-08 |
| Neoadjuvant Paclitaxel Poliglumex, Cisplatin and Radiation for Esophageal Cancer: A Phase II Trial (CTI#X64001) PPX with cisplatin and radiation - Esophageal Cancer | Phase 2 | Completed | Brown University | 40 | 2007-08-01 | 2020-02-17 |
| Paclitaxel Poliglumex and Estradiol in Treating Patients With Stage IV Prostate Cancer transdermal estradiol, paclitaxel poliglumex - Prostate Cancer | Phase 2 | Terminated | OHSU Knight Cancer Institute | 21 | 2007-02-01 | 2017-04-28 |
| Phase II Study of Combination of Paclitaxel Poliglumex and Alimta for Advanced Non-small Cell Lung Cancer (NSCLC) paclitaxel poliglumex, pemetrexed - Advanced Non-small Cell Lung Cancer | Phase 2 | Completed | Dartmouth-Hitchcock Medical Center | 14 | 2006-10-01 | 2014-01-09 |
| A Phase II Study of Radiation Therapy, Paclitaxel Poliglumex, and Carboplatin in Stage III Non-Small Cell Lung Cancer Paclitaxel poliglumex, Carboplatin, External beam radiation therapy - Carcinoma, Non-Small-Cell Lung | Phase 2 | Terminated | Washington University School of Medicine | 10 | 2006-04-01 | 2016-12-12 |
| Paclitaxel Poliglumex and Capecitabine in Treating Patients With Metastatic Breast Cancer capecitabine, paclitaxel poliglumex - Breast Cancer | Phase 2 | Completed | Alliance for Clinical Trials in Oncology | 48 | 2006-02-01 | 2016-12-06 |
| Efficacy and Safety Study of Xyotax to Treat Prostate Cancer Paclitaxel polyglumex (Xyotax) - Prostatic Neoplasms | Phase 2 | Completed | The Methodist Hospital Research Institute | 29 | 2005-03-01 | 2016-03-17 |
| Study of Xyotax (CT-2103) in Patients With Metastatic Breast Cancer CT-2103 (Xyotax) - Breast Cancer, Metastatic Breast Cancer | Phase 2 | Completed | Dana-Farber Cancer Institute | 45 | 2004-10-01 | 2007-12-21 |
| Phase II CT-2103/Carboplatin in Ovarian Cancer CT-2103 (poly(L)glutamate-paclitaxel), carboplatin - Ovarian Neoplasm | Phase 2 | Completed | CTI BioPharma | 82 | 2003-02-01 | 2008-09-22 |
| CT-2103 in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer or Primary Peritoneal Cancer Paclitaxel Poliglumex - Primary Peritoneal Carcinoma, Recurrent Ovarian Carcinoma | Phase 2 | Completed | Gynecologic Oncology Group | 78 | 2002-09-01 | 2017-07-13 |
| CT-2103 in Treating Patients With Recurrent Ovarian Epithelial or Fallopian Tube Cancer or Primary Peritoneal Cancer paclitaxel poliglumex - Fallopian Tube Cancer, Ovarian Cancer | Phase 1 / Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 2001-02-01 | 2013-05-30 |
Breast Neoplasms (3) · Ovarian Neoplasms (3) · Prostatic Neoplasms (2) · Brain Neoplasms (1) · Breast Neoplasms, Male (1) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Ovarian Epithelial (1) · Carcinoma, Squamous Cell (1) · Esophageal Neoplasms (1) · Fallopian Tube Neoplasms (1) · Glioblastoma (1) · Head and Neck Neoplasms (1)
Brown University (2) · Alliance for Clinical Trials in Oncology (1) · CTI BioPharma (1) · Dana-Farber Cancer Institute (1) · Dartmouth-Hitchcock Medical Center (1) · Gynecologic Oncology Group (1) · Memorial Sloan Kettering Cancer Center (1) · OHSU Knight Cancer Institute (1) · State University of New York - Upstate Medical University (1) · The Methodist Hospital Research Institute (1) · University of Southern California (1) · Washington University School of Medicine (1)
United States (12)
Howard Safran, MD (2) · Agustin Garcia, MD (1) · Edith A. Perez, MD (1) · James R Rigas, MD (1) · Lawrence N. Shulman, MD (1) · Paul Sabbatini (1) · Paul Sabbatini, MD (1) · Ramaswamy Govindan, M.D. (1) · Robert J Amato, DO (1) · Scott Stromatt, M.D. (1) · Seung Shin Hahn, MD (1) · Tomasz M. Beer, MD (1)
U10CA027469 (1)