20 completed, 5 unknown, 4 recruiting, 1 active not recruiting. 26 Not applicable, 3 Phase 4, 1 Early Phase 1, 1 Phase 2.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Machine Learning for Evaluating and Diagnosing Temporomandibular Disorders Low-Level Laser Acupuncture, Proprioceptive Training, Stabilization Splint Treatment - Temporomandibular Disorders (TMD), TMJ Disorder | Not applicable | Recruiting | En Chu Kong Hospital | 180 | 2026-10-09 | 2026-10-13 |
| Ultrasonographic Assessment of Muscle Echogenicity in Myofascial Pain occlusal splint, Lidocaine Hydrochloride 2% Injection Solution - Myofascial Pain | Not applicable | Completed | Istanbul Medipol University Hospital | 80 | 2026-05-16 | 2026-08-11 |
| Occlusal Splint Combined With Granisetron Injection for Management of Myofascial Pain Related to Temporomandibular Disorders Granisetron, lidocaine, occlusal splint - TMD, TMD/Orofacial Pain | Phase 4 | Active not recruiting | Mansoura University | 48 | 2026-01-27 | 2026-03-05 |
| 3D-Printed vs Conventional Acrylic Stabilization Splints in Young Adults With Bruxism and Temporomandibular Disorders: A Randomized Trial 3D-Printed Occlusal Splint (Voco V-Print), Conventional Acrylic Occlusal Splint - Bruxism, Sleep | Not applicable | Recruiting | Baskent University | 44 | 2026-01-12 | 2026-02-25 |
| Effect of an Occlusal Splint in Swimming Performance occlusal splint - the Aim of This Study Was to Evaluate the Effect of a Custom Occlusal Splint on Swimming Performance, Stroke Efficiency, and Heart Rate in Master Swimmers, Athletic Performance and the Impact on Performance Factors | Not applicable | Completed | Universidad Europea de Valencia | 20 | 2025-12-01 | 2026-07-13 |
| EMG-Based Evaluation of Occlusal Splint and Masseter Botox Effects on Head and Neck Muscles Botulinum toxin injection, Occlusal splint, Botulinum toxin + Occlusal splint combined - Myofascial Pain Syndrome (MPS), Masticatory Muscle Pain | Phase 4 | Recruiting | Istanbul University | 56 | 2025-09-01 | 2025-07-24 |
| ePROPP - eHealth for Preventing and Reducing Orofacial Pain in the Population Mobistudy Application, Occlusal splint - Temporomandibular Joint Disorder, Temporomandibular Disorders (TMDs) | Not applicable | Not yet recruiting | Malmö University | 120 | 2025-08-22 | 2025-08-05 |
| Occlusal Splint and Exercise Therapy for Temporomandibular Disorders Occlusal Splint, Exercise - Temporomandibular Disorders (TMD) | Not applicable | Recruiting | Acibadem University | 38 | 2025-07-10 | 2026-04-02 |
| Low-Level Laser Therapy Versus Occlusal Splint Therapy for Bruxism in Children Low-Level Laser Therapy (LLLT), Occlusal Splint - Bruxism, Sleep Bruxism | Not applicable | Completed | Ain Shams University | 30 | 2025-05-01 | 2026-10-16 |
| Evaluation of Postural Exercises in the Treatment of Temporomandibular Disorders occlusal splint, occlusal splints combined with rocabado exercise, occlusal splint combined with posture exercise - Occlusal Splints, Temporomandibular Disorders (TMD) | Not applicable | Completed | Istanbul University | 57 | 2024-11-01 | 2026-01-21 |
| Short-Term Symptom Changes in Adults With Teeth Clenching or Grinding and Jaw Symptoms Receiving Splint, Botulinum Toxin, or Medication Plus Splint Care Occlusal splint, Botulinum Toxin Type A (Dysport®), Thiocolchicoside - Bruxism, Temporomandibular Disorders (TMD) | Completed | Recep Tayyip Erdogan University | 60 | 2024-08-05 | 2026-07-30 | |
| Multimodal Physiotherapy Versus Occlusal Splint in Adults With Temporomandibular Disorders Multimodal Physiotherapy, Occlusal Splint - Temporomandibular Disorders (TMD) | Not applicable | Completed | Egas Moniz - Cooperativa de Ensino Superior, CRL | 24 | 2024-02-23 | 2026-03-03 |
| Digitally Trained Applied Relaxation for Treatment of Temporomandibular Pain Applied Relaxation, Occlusal splint - Temporomandibular Disorders (TMD) | Not applicable | Enrolling by invitation | University of Oulu | 124 | 2024-01-08 | 2025-09-11 |
| Effect of Different Treatment Techniques on Masseter Muscle Thickness Occlusal splint, preventive advice, Botulinum toxin - Bruxism, Masseter Muscle Hypertrophy | Not applicable | Completed | Zonguldak Bulent Ecevit University | 48 | 2023-04-03 | 2024-09-19 |
| The Use of Earplugs on Temporomandibular Joint Earplug, occlusal splint, exercise - Ear Protective Devices, Temporomandibular Joint Disorders | Not applicable | Completed | Istanbul University | 120 | 2023-04-01 | 2024-04-02 |
| Conservative Therapies in the Treatment of Temporomandibular Disorders Occlusal Splint, Laser Therapy, Acupuncture Laser Therapy - Temporomandibular Joint Disorders, Temporomandibular Joint Pain | Not applicable | Completed | Universidade Federal de Alfenas | 160 | 2023-03-01 | 2026-05-26 |
| Evaluation of Digital Stabilizing Splint in Management of Masticatory Muscle Disorder digital stabilizing splint - Muscle Disorder | Not applicable | Completed | zahraa hassan | 8 | 2022-09-30 | 2023-11-18 |
| Occlusal Splints in the Treatment of Sleep Bruxism Occlusal splint - Sleep Bruxism, Adult, Splints | Not applicable | Completed | Istanbul University | 100 | 2021-08-06 | 2022-06-22 |
| Comparative Study of Maxillary and Mandibular Splints Used for the Treatment of Masticatory Muscle Parafunction (FEA) Occlusal splint - Jaw, Edentulous, Mouth, Edentulous | Not applicable | Unknown | Moscow State University of Medicine and Dentistry | 12 | 2021-07-16 | 2022-04-18 |
| Effectiveness of Arthrocentesis and the Occlusal Splint in Treatment of the TMJ Occlusal splint, Arthrocentesis - Temporomandibular Joint Disc Displacement, Anterior Disc Displacement | Not applicable | Completed | University of Sao Paulo General Hospital | 24 | 2021-05-30 | 2024-02-13 |
Showing 20 of 32. Sign in to see all of them.
Temporomandibular Joint Disorders (16) · Bruxism (9) · Sleep Bruxism (6) · Facial Pain (5) · Myalgia (2) · Chronic Pain (1) · Jaw, Edentulous (1) · Masticatory Muscles, Hypertrophy of (1) · Mouth, Edentulous (1) · Muscular Diseases (1) · Myofascial Pain Syndromes (1) · Pain (1) · Sleep Initiation and Maintenance Disorders (1) · Tic Disorders (1) · Tourette Syndrome (1)
Istanbul University (4) · University of Nove de Julho (3) · Ankara University (2) · Malmö University (2) · Acibadem University (1) · Ain Shams University (1) · Baskent University (1) · Cairo University (1) · Croatian Science Foundation (1) · Egas Moniz - Cooperativa de Ensino Superior, CRL (1) · En Chu Kong Hospital (1) · Federal University of Pelotas (1) · Istanbul Medipol University Hospital (1) · Lukasz Adamczyk (1) · Mansoura University (1)
Turkey (Türkiye) (10) · Brazil (5) · Egypt (4) · Croatia (1) · Finland (1) · Poland (1) · Portugal (1) · Russia (1) · Spain (1) · Taiwan (1) · United States (1)
Ching-Mao Chang, MD, PhD (1) · Ching-Po Lin, PhD (1) · Cid Gomes, MSc (1) · Daniel Almeida, PhD (1) · Dina Elawady, PHD (1) · Ebru K Mutlu, Clinical Prof. (1) · Helin Yavuz, Physiotherapist (1) · Iva Z Alajbeg, PhD (1) · Lukasz Adamczyk, DMD (1) · Mieszko Wieckiewicz, DMD, MSc, PhD (1) · Mona S Fayed, PHD (1) · Per Alstergren, Professor (1)
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