34 completed, 7 unknown, 3 terminated, 1 active not recruiting. 24 Not applicable, 12 Phase 1, 4 Phase 2, 4 Phase 3, 2 Phase 4.
Follow Negative control: new trials by email Literature Review of Negative control trials Research Report on Negative control
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Avocado and Postprandial Responses Negative control, Avocado, Fat and fiber addition - Healthy, Healthy Volunteer | Not applicable | Completed | University of Vermont Medical Center | 30 | 2025-03-24 | 2026-07-22 |
| Clinical Study to Assess the Efficacy of Professional Tooth Whitening Maintenance System whitening maintenance, whitening maintenance MW, negative control - Staining | Not applicable | Completed | Colgate Palmolive | 93 | 2024-10-07 | 2025-05-21 |
| Anti-gingivitis Mouthrinse Amine/zinc lactate/fluoride system, negative control - Gingivitis | Phase 3 | Completed | Colgate Palmolive | 90 | 2024-03-06 | 2025-05-21 |
| Dapagliflozin in Nonalcoholic Fatty Liver Disease (NAFLD) and Type 2 Diabetes Mellitus Patients (T2DM). Dapagliflozin (DAPA), Placebo, Negative control - Diabetes Mellitus, Non Alcholic Fatty Liver Disease | Phase 1 / Phase 2 | Active not recruiting | Amira Bisher,PhD | 60 | 2024-01-15 | 2025-06-13 |
| Clinical and Microbiological Aspects of Probiotics in Non-surgical Periodontal Therapy. Experimental, Negative control, Positive control - Periodontitis, Probiotics | Not applicable | Unknown | G. d'Annunzio University | 70 | 2023-10-01 | 2023-10-04 |
| Probiotics in Special Needs Patients at High Risk for Tooth Decay: a Randomized Controlled Trial. Test Group, Positive Control, Negative Control - Tooth Decay, Intellectual Disability | Not applicable | Unknown | G. d'Annunzio University | 70 | 2023-10-01 | 2023-10-04 |
| Clinical Effects of Limosilactobacillus Reuteri Probiotics as an Adjunct to the Treatment of Periodontitis Probiotics, Negative control - Chronic Periodontitis, Generalized | Not applicable | Unknown | Universidade do Porto | 60 | 2023-02-01 | 2023-11-28 |
| Primary Irritation Patch Test (PIPT) Study Conducted at NovoBliss Research for Shared Panel Peptide complexed HA Age Defying Gel with Vitamin C & Niacinamide, Peptide complexed HA Age Defying Gel with Natural Extracts, Peptide complexed HA Age Defying Gel with Vitamin C & Natural Extracts - Healthy | Not applicable | Unknown | NovoBliss Research Pvt Ltd | 26 | 2022-12-05 | 2022-12-14 |
| Influence of Hyaluronic Acid in the Healing of Palatal Donor Sites During Free Gingival Graft Procedures Test - xHyA, Negative control - Palatal Donor Site Wound Healing, Palatal Wound | Not applicable | Completed | University of Milan | 20 | 2022-09-05 | 2026-03-09 |
| Interest of Nasal Provocation Tests for Diagnosis of House Mites Allergic Rhinitis Nasal provocation test - 725 Dermatophagoides Pteronyssinus, Negative control - Mite Allergy, Respiratory Disease | Phase 4 | Terminated | Centre Hospitalier Régional Metz-Thionville | 8 | 2022-03-07 | 2024-08-09 |
| Fibrin Glue Versus Titanium Platelet-rich Fibrin in Lateral Sinus Lifting Fibrin Glue, T-PRF, Negative control - Sinus Floor Augmentation, Graftless Sinus Elevation | Not applicable | Completed | Hams Hamed Abdelrahman | 30 | 2022-02-01 | 2023-04-26 |
| Evaluation in a Multimodal Structured Curriculum of Laparoscopic Surgery Surgical Training Intervention, Positive Control, Negative Control - Medical Education, Laparoscopic Surgery | Not applicable | Completed | University of Los Andes, Columbia | 37 | 2022-01-28 | 2024-08-30 |
| A Study to Evaluate the Skin Irritation Potential of PBI-100 Topical Cream in Healthy Participants PBI-100 Topical Cream, Positive Control - Sodium laurel sulfate (SLS), PBI-100 Topical Cream, Vehicle - Healthy Volunteers | Phase 1 | Completed | Pyramid Biosciences | 30 | 2021-04-12 | 2022-01-27 |
| Evaluation of SARS-COV-2 Viral Load of Covid-19 Patients After Rinsing With Oral Antimicrobial Mouthwashes CPC+ZN, CPC, Negative Control - Covid19 | Not applicable | Completed | Hospital Israelita Albert Einstein | 105 | 2021-04-04 | 2022-03-11 |
| Basil Extract (Ocimum Basilicum) in the Management of Recurrent Aphthous Stomatitis use of basil extract gel in treatment of aphthus ulcer, muco adhesive placebo gel, no treatment - Oral Ulcer | Phase 2 | Unknown | Tanta University | 30 | 2021-01-01 | 2021-07-14 |
| 4-Day Primary Irritation Patch Test of MIS Solution NS Solution, Normal Saline, SLS - Healthy, Irritation/Irritant | Not applicable | Completed | Next Science TM | 33 | 2020-07-06 | 2023-11-07 |
| Irritation Potential of Omeza Collagen Matrix Using Modified HRIPT Test Article, Negative Control - Erythema, Sensitisation | Not applicable | Completed | Omeza, LLC | 58 | 2019-12-02 | 2023-05-17 |
| Effect of Degree of Polymerization and Linkage of α-glucans on Post-prandial Glucose Response Roquette Glucidex 2, Pharmacosmos Dextran 10, Roquette Glucidex 40 - Postprandial Glucose Response | Not applicable | Completed | Société des Produits Nestlé (SPN) | 10 | 2019-11-29 | 2022-03-04 |
| Allergy Potential of Omeza Collagen Matrix in Human Subjects Using the Skin Prick Method Test Article, Positive Control, Negative Control - Allergic Reaction | Not applicable | Completed | Omeza, LLC | 25 | 2019-11-14 | 2020-08-12 |
| Effect of Nano Care Gold on Marginal Integrity of Resin Composite Nano Care Gold, No intervention, Chlorhexidine - Caries Class Ii | Phase 1 | Completed | Cairo University | 57 | 2019-11-01 | 2021-03-23 |
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Hypersensitivity (2) · Signs and Symptoms, Digestive (2) · Surgical Wound Infection (2) · Alopecia (1) · COVID-19 (1) · Carcinoma, Non-Small-Cell Lung (1) · Chronic Periodontitis (1) · Communicable Diseases (1) · Dental Caries (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Dwarfism (1) · Erythema (1) · Gingivitis (1) · Intellectual Disability (1)
GlaxoSmithKline (4) · Cargill (2) · Colgate Palmolive (2) · Da Volterra (2) · G. d'Annunzio University (2) · Omeza, LLC (2) · Société des Produits Nestlé (SPN) (2) · Windtree Therapeutics (2) · Zurex Pharma, Inc. (2) · Amira Bisher,PhD (1) · Bayer (1) · Becton, Dickinson and Company (1) · Cairo University (1) · Centre Hospitalier Régional Metz-Thionville (1) · Changchun GeneScience Pharmaceutical Co., Ltd. (1)
United States (17) · Egypt (4) · Germany (4) · China (3) · France (3) · Italy (3) · Brazil (2) · Switzerland (2) · Canada (1) · Colombia (1) · Portugal (1) · Romania (1) · United Kingdom (1)
Marco Dolci, MD DDS PHD (2) · Debora H Douek, PhD (1) · Dr Nayan K Patel, MBBS (1) · Duc A Tran, MD PhD (1) · Elisabeth Kruse, PhD (1) · Esther Campbell (1) · Evelyn J Ellis-Grosse, PhD (1) · Gabriela Bergonzelli, PhD (1) · Harvinder S Gill, PhD (1) · Jana Kraft, Ph.D. (1) · Junfen Fu, Doctor (1)
PMID 29186529, PMID 31249709, PMID 32026625, PMID 35573994
2005 (1), 2018 (1)