10 completed, 6 terminated, 1 recruiting, 1 unknown. 18 Phase 1, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 18 | Completed 10, Terminated 6, Recruiting 1, Unknown 1 |
| Phase 2 | 7 | Terminated 5, Completed 1, Recruiting 1 |
Follow Navelbine: new trials by email Literature Review of Navelbine trials Research Report on Navelbine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vinorelbine With Trastuzumab Emtansine in Pre-Treated HER2-Positive Metastatic Breast Cancer Vinorelbine, Trastuzumab Emtansine - Breast Cancer, Metastatic Breast Cancer | Phase 1 / Phase 2 | Terminated | University of Miami | 2 | 2017-04-12 | 2019-04-17 |
| European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors Ribociclib, Topotecan, Temozolomide - Pediatric Cancer | Phase 1 / Phase 2 | Recruiting | Gustave Roussy, Cancer Campus, Grand Paris | 472 | 2016-08-03 | 2026-07-10 |
| the"Fuzheng" Therapy of TCM to Improve the Survival Quality of Early-stage NSCLC by Intervening the CTCs JinFuKang, Cisplatin, Pemetrexed - Non-small Cell Lung Cancer(NSCLC) | Phase 1 | Completed | Shanghai University of Traditional Chinese Medicine | 218 | 2015-06-01 | 2019-09-20 |
| Study of Pembrolizumab Plus Chemotherapy in Patients With Advanced Cancer (PembroPlus) Pembrolizumab, Gemcitabine, Docetaxel - Advanced Cancer, Breast Cancer | Phase 1 / Phase 2 | Terminated | Western Regional Medical Center | 81 | 2014-12-01 | 2018-07-02 |
| Study of Combination of PIGEV Before Autologous Stem Cell Transplant in Patients With Hodgkin's Lymphoma panobinostat, Ifosfamide, Gemcitabine - Hodgkin's Lymphoma | Phase 1 | Unknown | Armando Santoro, MD | 24 | 2011-07-01 | 2014-01-29 |
| Pazopanib + Vinorelbine in Non Small Cell Lung Cancer (NSCLC) and Breast Cancer Pazopanib, Vinorelbine - Metastatic Non Small Cell Lung Cancer, Metastatic Breast Cancer | Phase 1 | Terminated | Northwestern University | 8 | 2010-02-01 | 2013-10-30 |
| Study of Oral Vinorelbine and Erlotinib in Non-Small Cell Lung Cancer Vinorelbine (Navelbine), Erlotinib - Non-Small Cell Lung Cancer | Phase 1 | Completed | National Cancer Centre, Singapore | 30 | 2008-04-01 | 2012-10-19 |
| Lapatinib and Vinorelbine in Treating Women With HER2-Overexpressing Locally Advanced or Metastatic Breast Cancer Lapatinib, vinorelbine - Breast Cancer | Phase 1 | Completed | UNICANCER | 33 | 2007-06-01 | 2014-01-14 |
| Melphalan, Yttrium Y 90 Ibritumomab Tiuxetan, and Rituximab Followed by Autologous Stem Cell Transplant in Treating Older Patients With Non-Hodgkin's Lymphoma That Has Relapsed or Not Responded to Previous Treatment ibritumomab tiuxetan, rituximab, melphalan - Lymphoma | Phase 1 | Completed | Swiss Cancer Institute | 20 | 2006-10-01 | 2019-05-15 |
| Post-transplant Autologous Cytokine-induced Killer (CIK) Cells for Treatment of High Risk Hematologic Malignancies CIK cells, etoposide, bcnu - Leukemia, Multiple Myeloma | Phase 1 | Completed | Sally Arai | 22 | 2006-05-01 | 2017-01-11 |
| Lapatinib and Vinorelbine in Treating Patients With Advanced Solid Tumors lapatinib ditosylate, vinorelbine ditartrate, comparative genomic hybridization - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | University of California, Davis | 22 | 2005-12-01 | 2012-04-19 |
| A Phase I/II Study of ABI-007 (Abraxane®, Nab®-Paclitaxel)and Vinorelbine in Patients With Stage IV (Metastatic) Breast Cancer ABI-007, vinorelbine, Trastuzumab - Stage IV (Metastatic) Breast Cancer | Phase 1 / Phase 2 | Terminated | Celgene | 16 | 2005-08-01 | 2019-11-26 |
| Navelbine and Capecitabine in the Treatment of Metastatic Breast Cancer Navelbine, Capecitabine - Breast Cancer | Phase 1 | Completed | Dana-Farber Cancer Institute | 40 | 2002-03-01 | 2013-02-07 |
| Navelbine, Taxol, Herceptin and Neupogen in Stage IV Breast Cancer: A Phase I - II Trial Paclitaxel, Vinorelbine, Herceptin - Breast Cancer | Phase 1 / Phase 2 | Terminated | University of Washington | 38 | 2001-03-01 | 2017-07-17 |
| Phase I-II Study of Carboplatin, Vinorelbine and Capecitabine in Patients With Metastatic Breast Cancer Carboplatin, Capecitabine, Vinorelbine - Breast, Cancer | Phase 1 / Phase 2 | Completed | University of New Mexico | 33 | 2000-05-01 | 2010-01-07 |
| Chemotherapy Plus Trastuzumab in Treating Patients With Breast Cancer trastuzumab, vinorelbine ditartrate - Breast Cancer | Phase 1 | Completed | Dartmouth-Hitchcock Medical Center | 13 | 1999-11-01 | 2013-03-14 |
| Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer carboplatin, Gemcitabine, paclitaxel - Lung Cancer | Phase 1 / Phase 2 | Terminated | Northwestern University | 36 | 1999-08-01 | 2012-06-06 |
| Concomitant Chemoradiotherapy With Weekly Paclitaxel and Vinorelbine and Granulocyte Colony Stimulating Factor (GCSF) Support in Patients With Advanced Breast Cancer Paclitaxel, Vinorelbine, Filgrastim - Breast Cancer | Phase 1 | Completed | University of Chicago | 26 | 1999-06-01 | 2014-03-07 |
Breast Neoplasms (9) · Carcinoma, Non-Small-Cell Lung (4) · Lung Neoplasms (3) · Lymphoma (2) · Neoplasms (2) · Burkitt Lymphoma (1) · Hodgkin Disease (1) · Leukemia (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Lymphoma, B-Cell, Marginal Zone (1) · Lymphoma, Follicular (1) · Lymphoma, Large B-Cell, Diffuse (1) · Lymphoma, Large-Cell, Immunoblastic (1) · Lymphoma, Mantle-Cell (1) · Lymphoma, Non-Hodgkin (1)
Northwestern University (2) · Armando Santoro, MD (1) · Celgene (1) · Dana-Farber Cancer Institute (1) · Dartmouth-Hitchcock Medical Center (1) · Gustave Roussy, Cancer Campus, Grand Paris (1) · National Cancer Centre, Singapore (1) · Sally Arai (1) · Shanghai University of Traditional Chinese Medicine (1) · Swiss Cancer Institute (1) · UNICANCER (1) · University of California, Davis (1) · University of Chicago (1) · University of Miami (1) · University of New Mexico (1)
United States (12) · France (2) · Italy (2) · Denmark (1) · Netherlands (1) · Singapore (1) · Spain (1) · Switzerland (1) · United Kingdom (1)
Angelika Bischof Delaloye, Prof (1) · Armando Santoro, MD (1) · Ashish Sangal, MD (1) · Birgit Geoerger, MD (1) · Craig A. Bunnell, MD (1) · Gregory A. Masters, MD (1) · Helen K. Chew, MD (1) · Ian Rabinowitz, MD (1) · Julie R. Gralow, M.D. (1) · Jyoti D Patel, MD (1) · Michele Ghielmini, Prof (1) · Michele Voegeli, MD (1) · Peter A. Kaufman, MD (1) · Pierre Fumoleau, MD, PhD (1) · Reshma Mahtani, DO (1)
PMID 15246197, PMID 27135612, PMID 27677906, PMID 29119276, PMID 31538815, PMID 33892407, PMID 34347542, PMID 34543871, PMID 35292802, PMID 41838385, PMID 42686334
2005 (1), 2016 (1), P30CA023108 (1), P30CA093373 (1)