5 completed, 2 recruiting, 1 active not recruiting, 1 unknown. 6 Not applicable, 3 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 2, Recruiting 2, Active not recruiting 1, Unknown 1 |
| Phase 4 | 3 | Completed 3 |
Follow nattokinase: new trials by email Literature Review of nattokinase trials Research Report on nattokinase
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Nattokinase Supplementation on Strength Recovery and Muscle Damage Biomarkers Following Exercise-Induced Muscle Injury: A Pilot Study Nattokinase, Placebo - Exercise-induced Muscle Damage | Not applicable | Active not recruiting | National Taiwan Sport University | 14 | 2026-09-03 | 2026-09-23 |
| Effects of Nattokinase on Cardiovascular Risk, Gut Microbiota, Sleep, and Cognition in Metabolic Syndrome With Sleep Disorders. Nattokinase, Placebo - Metabolic Syndrome, Sleeping Disorders | Not applicable | Recruiting | Taipei Medical University | 80 | 2025-03-15 | 2025-11-17 |
| Effects of Nattokinase on Inflammation and Cardiovascular Risk Markers in Patients With Dyslipidemia Nattokinase, Placebo - Cardiovascular Diseases, Dyslipidemias | Not applicable | Recruiting | Universidade Federal Fluminense | 48 | 2024-08-03 | 2026-05-14 |
| Improving Cerebral Blood Flow and Cognitive Function in Patients With Asymptomatic Intracranial / Carotid Stenosis With Nattokinase (ICC-PACS) Nattokinase, Placebo - Cerebral Blood Flow, Cognitive Function | Not applicable | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 100 | 2022-01-13 | 2023-04-18 |
| Nattokinase Supplementation and Hemostatic Factors Nattokinase, Placebo - Hypercholesterolemia | Phase 4 | Completed | Yonsei University | 100 | 2015-05-01 | 2016-09-23 |
| Nattokinase Atherothrombotic Prevention Study Nattokinase, Placebo - Prevention of Subclinical Atherosclerosis Progression, Prevention of Cognitive Decline | Not applicable | Completed | University of Southern California | 265 | 2014-04-01 | 2024-03-19 |
| Effects of NSK-SD (Nattokinase) on Blood Pressure NSK-SD (nattokinase), Placebo - Hypertension | Phase 4 | Completed | Natural Immune Systems Inc | 79 | 2012-03-01 | 2016-09-01 |
| Efficacy and Safety of Geneferm Nattokinase Nattokinase - Hyperlipidemia | Not applicable | Completed | Chi Mei Medical Hospital | 47 | 2007-05-01 | 2008-09-09 |
| Efficacy and Safety of Natto Extract Natto extract (Nattokinase) - Thrombosis, Cardiovascular Diseases | Phase 4 | Completed | Changhua Christian Hospital | 45 | 2005-06-01 | 2007-03-14 |
Cardiovascular Diseases (3) · Thrombosis (2) · Atherosclerosis (1) · Carotid Stenosis (1) · Dyslipidemias (1) · Hypercholesterolemia (1) · Hyperlipidemias (1) · Hypertension (1) · Inflammation (1) · Metabolic Syndrome (1) · Parasomnias (1)
Changhua Christian Hospital (1) · Chi Mei Medical Hospital (1) · National Taiwan Sport University (1) · Natural Immune Systems Inc (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · Taipei Medical University (1) · Universidade Federal Fluminense (1) · University of Southern California (1) · Yonsei University (1)
Taiwan (4) · Brazil (1) · China (1) · South Korea (1) · United States (1)
Chien-Hsun Hsia, MD (1) · Gitte S Jensen, PhD (1) · Howard N. Hodis, M.D. (1) · Jong Ho Lee, Ph.D. (1) · Ludmila Cardozo, PhD (1) · Nae-Cherng Yang, PhD (1)