4 completed, 1 not yet recruiting, 1 unknown. 6 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 4, Not yet recruiting 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow nalmefene: new trials by email Literature Review of nalmefene trials Research Report on nalmefene
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| TH104 for the Treatment of Pruritus in Primary Biliary Cholangitis Nalmefene, Placebo - Pruritus, Primary Biliary Cholangitis | Phase 2 | Not yet recruiting | Tharimmune Inc | 40 | 2026-06-01 | 2025-09-09 |
| St. PETERsburg Pain and Alcohol Intervention With Naltrexone and Nalmefene Low dose naltrexone, Nalmefene - HIV Infection, Alcohol Use | Phase 1 / Phase 2 | Completed | Boston Medical Center | 11 | 2018-07-03 | 2020-08-24 |
| Evaluation of Nalmefene in Impulse Control Disorders in Parkinson's Disease: A Prospective Open Label Study Nalmefene - Impulse Control Disorders, Parkinson Disease | Phase 2 | Unknown | University Hospital, Clermont-Ferrand | 30 | 2016-12-01 | 2016-10-17 |
| Nalmefene, Baclofen and Impulsivity in Subjects With Alcohol Use Disorder and Healthy Control Subjects Nalmefene, Baclofen, Placebo Oral Capsule - Alcohol Use Disorder | Phase 2 | Completed | Prof. Daniele Zullino | 37 | 2016-07-01 | 2020-10-29 |
| Nalmefene Smoking Cessation Study nalmefene, Placebo - Smoking Cessation | Phase 2 | Completed | Somaxon Pharmaceuticals | 76 | 2005-09-01 | 2008-05-19 |
| Nalmefene Gambling Study: Study of Nalmefene HCl in the Treatment of Pathological Gambling nalmefene HCl, Placebo - Pathological Gambling | Phase 2 / Phase 3 | Completed | Somaxon Pharmaceuticals | 233 | 2005-08-01 | 2008-05-19 |
Alcohol Drinking (1) · Alcoholism (1) · Disruptive, Impulse Control, and Conduct Disorders (1) · Gambling (1) · HIV Infections (1) · Impulsive Behavior (1) · Liver Cirrhosis, Biliary (1) · Pain (1) · Parkinson Disease (1) · Pruritus (1) · Smoking Cessation (1)
Somaxon Pharmaceuticals (2) · Boston Medical Center (1) · Prof. Daniele Zullino (1) · Tharimmune Inc (1) · University Hospital, Clermont-Ferrand (1)
France (1) · Russia (1) · Switzerland (1) · United States (1)
Philip Jochelson, MD (2) · Daniele F Zullino, MD (1) · Jeffrey H. Samet, MD, MA, MPH (1)
2015 (1), 2016 (1), UH2AA026193 (1)