3 unknown, 2 recruiting, 1 active not recruiting, 1 completed. 4 Phase 2, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Recruiting 2, Active not recruiting 1, Unknown 1 |
| Not applicable | 1 | Completed 1 |
Follow Mutation Carrier Screening: new trials by email Literature Review of Mutation Carrier Screening trials Research Report on Mutation Carrier Screening
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial) Allogeneic Hematopoietic Stem Cell Transplantation, Azacitidine, Best Practice - Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm | Phase 2 | Recruiting | National Cancer Institute (NCI) | 2000 | 2024-06-18 | 2026-10-30 |
| Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial Alpelisib, Binimetinib, Biopsy Procedure - Advanced Malignant Solid Neoplasm, Anatomic Stage III Breast Cancer AJCC v8 | Phase 2 | Recruiting | National Cancer Institute (NCI) | 2900 | 2023-04-07 | 2026-10-30 |
| Universal Endometrial Cancer DNA Sequencing for Detection of Lynch Syndrome and Personalized Care Genetic Counseling, Genetic Testing, Laboratory Biomarker Analysis - Endometrial Adenocarcinoma, Endometrial Carcinoma | Not applicable | Completed | Ohio State University Comprehensive Cancer Center | 1001 | 2018-03-30 | 2025-10-03 |
| Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial) Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration and Biopsy - Advanced Malignant Solid Neoplasm, Ann Arbor Stage III Non-Hodgkin Lymphoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 1377 | 2017-07-31 | 2026-07-24 |
| Prostate Cancer Screening and Dietary Heterocyclic Amines in African American Men physiologic testing, study of socioeconomic and demographic variables, evaluation of cancer risk factors - Prostate Cancer | Phase 2 | Unknown | Lawrence Livermore National Laboratory at University of California | 800 | 2002-03-01 | 2013-09-20 |
| Study of Families With Melanoma gene expression analysis, mutation analysis, immunohistochemistry staining method - Melanoma (Skin) | Unknown | Leeds Cancer Centre at St. James's University Hospital | 3700 | 2000-07-01 | 2013-08-12 | |
| Identifying Gene Mutations in Patients With Melanoma and in Families With a History of Hereditary Melanoma gene expression analysis, microarray analysis, molecular genetic technique - Hereditary Multiple Melanoma, Melanoma (Skin) | Unknown | Leeds Cancer Centre at St. James's University Hospital | 5000 | 1989-01-01 | 2013-08-12 |
Endometrial Neoplasms (2) · Melanoma (2) · Central Nervous System Neoplasms (1) · Colorectal Neoplasms, Hereditary Nonpolyposis (1) · Ependymoma (1) · Fallopian Tube Neoplasms (1) · Glioma (1) · Hepatoblastoma (1) · Histiocytic Sarcoma (1) · Histiocytosis, Langerhans-Cell (1) · Leukemia, Myeloid, Acute (1) · Lymphoma, Non-Hodgkin (1) · Medulloblastoma (1) · Melanoma, Cutaneous Malignant (1) · Myelodysplastic Syndromes (1)
National Cancer Institute (NCI) (3) · Leeds Cancer Centre at St. James's University Hospital (2) · Lawrence Livermore National Laboratory at University of California (1) · Ohio State University Comprehensive Cancer Center (1)
United States (5) · Puerto Rico (3) · Canada (2) · United Kingdom (2) · Australia (1)
Julia Newton Bishop, MD (2) · Donald W Parsons (1) · James M Ford (1) · Jerald P Radich (1) · Kenneth T. Bogen, DrPH, MPH, MA, ScD (1) · Paul Goodfellow (1)
PMID 33591402, PMID 35353553, PMID 36902217, PMID 41166674, PMID 42686334
U10CA180820 (1), U10CA180886 (1), U10CA180888 (1)