Mutation analysis: Clinical Trials

119 trials of Mutation analysis, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

84 completed, 24 unknown, 5 terminated, 4 withdrawn. 19 Phase 2, 13 Phase 1, 5 Not applicable, 5 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 219Completed 15, Unknown 3, Terminated 1
Phase 113Completed 10, Unknown 2, Terminated 1
Not applicable5Completed 2, Active not recruiting 1, Terminated 1, Unknown 1
Phase 35Unknown 3, Completed 2

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Natural History Study of FDXR Mutation-related Mitochondriopathy
Mutation analysis - Neurodegenerative Disease, Hereditary, Mitochondrial Diseases
CompletedState University of New York at Buffalo332020-11-032024-03-08
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy
Mutation analysis - Neurodegenerative Disease, Hereditary, Mitochondrial Diseases
CompletedState University of New York at Buffalo92020-11-032024-03-08
A Study on the Prevalence of Mutation of Cerebrotendinous Xanthomatosis (CTX)
Mutation Analysis - Xanthomatosis, Cerebrotendinous
UnknownTRPHARM8002019-12-012021-04-01
Mutation of BRCA1/2 and Other Potential Genes in Triple-negative Breast Cancer
Mutation analysis - Breast Cancer
Not applicableUnknownFudan University1002016-01-012016-02-02
High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia
Chemosensitivity Assay, Cytology Specimen Collection Procedure, Gene Expression Analysis - Recurrent Acute Leukemia of Ambiguous Lineage, Recurrent Acute Lymphoblastic Leukemia
Not applicableCompletedUniversity of Washington342015-09-112022-06-30
Genomic Profiling in Recommending Treatment for Patients With Metastatic Solid Tumors
mutation analysis, cytology specimen collection procedure, laboratory biomarker analysis - Unspecified Adult Solid Tumor, Protocol Specific
RecruitingStanford University1002014-07-282025-12-24
Biomarkers in Samples From Young Patients With Acute Myeloid Leukemia
gene expression analysis, mutation analysis, flow cytometry - Leukemia
CompletedChildren's Oncology Group1492013-02-012016-05-18
Studying Biomarkers in Samples From Patients With Recurrent or Metastatic Head and Neck Cancer Treated on E1302 Trial
mutation analysis, polymerase chain reaction, polymorphism analysis - Head and Neck Cancer
CompletedEastern Cooperative Oncology Group1832012-06-012017-05-17
Studying Genes in Samples From Younger Patients With Rhabdomyosarcoma
mutation analysis, nucleic acid sequencing, laboratory biomarker analysis - Sarcoma
CompletedChildren's Oncology Group582012-04-012016-05-18
Studying Genes in Samples From Younger Patients With Ovarian or Testicular Sex Cord Stromal Tumors
RNA analysis, gene expression analysis, mutation analysis - Childhood Germ Cell Tumor, Leydig Cell Tumor
CompletedChildren's Oncology Group502012-04-012016-07-14
Studying Gene Expression in Samples From Patients With Rhabdoid Tumors
DNA analysis, gene expression analysis, mutation analysis - Brain and Central Nervous System Tumors, Kidney Cancer
CompletedChildren's Oncology Group252012-03-012016-07-14
Studying DNA in Samples From Younger Patients With Down Syndrome and Acute Myeloid Leukemia Treated on COG-AAML0431 Clinical Trial
gene mapping, microarray analysis, mutation analysis - Leukemia
CompletedChildren's Oncology Group102012-02-012016-05-18
Biomarkers in Blood Samples From Patients With Acute Myeloid Leukemia
mutation analysis, protein analysis, laboratory biomarker analysis - Leukemia
CompletedEastern Cooperative Oncology Group2202012-01-032017-05-19
Biomarkers in Blood and Tissue Samples From Patients With Epstein-Barr Virus-Positive Hodgkin Lymphoma
DNA analysis, RNA analysis, cytogenetic analysis - Lymphoma, Nonneoplastic Condition
CompletedChildren's Oncology Group502011-12-012016-05-17
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma
fluorescence in situ hybridization, gene expression analysis, microarray analysis - Neuroblastoma
CompletedChildren's Oncology Group52011-12-012016-07-11
Biomarkers in Tissue Samples From Patients With Ewing Sarcoma
DNA analysis, comparative genomic hybridization, gene expression analysis - Sarcoma
CompletedChildren's Oncology Group1662011-12-012015-05-12
S9031-9333-0106-0112-A Study of Biomarkers in Samples From Patients With Acute Myeloid Leukemia Treated With Standard Chemotherapy With or Without Gemtuzumab Ozogamicin
DNA analysis, RNA analysis, gene expression analysis - Leukemia
CompletedSWOG Cancer Research Network3652011-12-012015-03-06
Biomarkers in Patients With Head and Neck Cancer
cetuximab, cisplatin, DNA analysis - Head and Neck Cancer
CompletedECOG-ACRIN Cancer Research Group702011-11-212017-05-19
Studying Biomarkers in Samples From Younger Patients With Malignant Germ Cell Tumor Progression
DNA methylation analysis, RNA analysis, mutation analysis - Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor
CompletedChildren's Oncology Group902011-10-012016-05-18
Studying Genes in Samples From Younger Patients With Desmoplastic Small Round Cell Tumor Registered on COG-D9902 or COG-ABTR01B1
DNA analysis, RNA analysis, gene expression analysis - Sarcoma
CompletedChildren's Oncology Group202011-09-012016-05-18

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Conditions studied

Leukemia (29)  ·  Carcinoma, Non-Small-Cell Lung (15)  ·  Leukemia, Myeloid, Acute (13)  ·  Colonic Neoplasms (12)  ·  Lung Neoplasms (12)  ·  Breast Neoplasms (11)  ·  Colorectal Neoplasms (9)  ·  Congenital Abnormalities (9)  ·  Rectal Neoplasms (9)  ·  Kidney Neoplasms (8)  ·  Leukemia, Erythroblastic, Acute (7)  ·  Leukemia, Megakaryoblastic, Acute (7)  ·  Leukemia, Monocytic, Acute (7)  ·  Leukemia, Myelomonocytic, Acute (7)  ·  Melanoma (7)

Sponsors

Children's Oncology Group (22)  ·  Alliance for Clinical Trials in Oncology (11)  ·  ECOG-ACRIN Cancer Research Group (7)  ·  Case Comprehensive Cancer Center (5)  ·  Eastern Cooperative Oncology Group (5)  ·  Leeds Cancer Centre at St. James's University Hospital (5)  ·  City of Hope Medical Center (4)  ·  National Cancer Institute (NCI) (4)  ·  SWOG Cancer Research Network (4)  ·  Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (4)  ·  University of Nebraska (3)  ·  Abramson Cancer Center at Penn Medicine (2)  ·  Cancer Trials Ireland (2)  ·  Medical Research Council (2)  ·  National Institutes of Health Clinical Center (CC) (2)

Countries

United States (49)  ·  United Kingdom (13)  ·  Ireland (3)  ·  Australia (2)  ·  Canada (2)  ·  France (2)  ·  Italy (2)  ·  Belgium (1)  ·  China (1)  ·  Germany (1)  ·  Iceland (1)  ·  Israel (1)  ·  Portugal (1)  ·  Puerto Rico (1)  ·  Singapore (1)

Top investigators

Julia Newton Bishop, MD (4)  ·  Adolfo A. Ferrando, MD, PhD (2)  ·  Anjali Advani, MD (2)  ·  Balazs Halmos, MD (2)  ·  Brenda Cooper, MD (2)  ·  Christine B. Ambrosone, PhD (2)  ·  Dana A. Hill, MD (2)  ·  Jill Kolesar, PharmD (2)  ·  Ralph Hauke, MD (2)  ·  Taosheng Huang (2)  ·  Wendell G. Yarbrough, MD, FACS (2)  ·  William D. Figg, PharmD (2)  ·  Afshin Dowlati, MD (1)  ·  Alan K. Burnett, MD, FRCP (1)  ·  Alberto S. Pappo, MD (1)

Results publications

PMID 12622604, PMID 12860943, PMID 14701766, PMID 14726676, PMID 15386381, PMID 15662127, PMID 16299243, PMID 18090584, PMID 18094376, PMID 18223210, PMID 19770416, PMID 20309628, PMID 20442368, PMID 21169260, PMID 21204803, PMID 24360787, PMID 24383844, PMID 24831979, PMID 25361995, PMID 25527568, PMID 25870087, PMID 26715442, PMID 26882907, PMID 26898607, PMID 28925785, PMID 31375516, PMID 32994442, PMID 33555272, PMID 34162404, PMID 34847232, PMID 36823396, PMID 37196637, PMID 38017103, PMID 38702786, PMID 39283025

NIH funding

P30CA043703 (4), U10CA031946 (4), P30CA036727 (3), U10CA032102 (3), P30CA033572 (2), P30CA068485 (2), U01CA062475 (2), 2008 (1), P30CA012197 (1), P30CA014236 (1), P30CA014520 (1), P30CA015704 (1), P30CA093373 (1), R01CA129382 (1), RC1CA145707 (1)