164 recruiting, 134 active not recruiting, 56 completed, 27 not yet recruiting. 444 Phase 2, 70 Phase 1, 28 Phase 3.
Follow Mri: new trials by email Literature Review of Mri trials Research Report on Mri
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Preoperative Durvalumab, Cisplatin, Gemcitabine With or Without Futibatinib Targeted Therapy for the Treatment of Resectable Intrahepatic Cholangiocarcinoma, OPTIC Trial Biospecimen Collection, Cisplatin, Computed Tomography - Resectable Intrahepatic Cholangiocarcinoma | Phase 2 | Not yet recruiting | Northwestern University | 44 | 2027-12-10 | 2026-06-10 |
| Zanubrutinib and Sonrotoclax for the Treatment of Relapsed Chronic Lymphocytic Leukemia /Small Lymphocytic Leukemia, ZeuS-2 Trial Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | Phase 2 | Not yet recruiting | City of Hope Medical Center | 44 | 2027-08-04 | 2026-09-10 |
| Testing the Addition of Iberdomide to Therapy in People With Neuroblastoma That Has Come Back, Not Responded to Treatment, or Gotten Worse Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography - Recurrent Ganglioneuroblastoma, Recurrent Neuroblastoma | Phase 1 / Phase 2 | Recruiting | National Cancer Institute (NCI) | 76 | 2027-06-25 | 2026-10-22 |
| Zipalertinib With Carboplatin and Pemetrexed for the Treatment of Resectable, Stage II-IIIB, Non-Small Cell Lung Cancer Biospecimen Collection, Carboplatin, Computed Tomography - Lung Non-Squamous Non-Small Cell Carcinoma | Phase 2 | Not yet recruiting | Jonsson Comprehensive Cancer Center | 16 | 2027-06-01 | 2026-02-05 |
| A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information Biospecimen Collection, Chest Radiography, Computed Tomography - Clinical Stage 0 Cutaneous Melanoma AJCC v8, Clinical Stage I Cutaneous Melanoma AJCC v8 | Phase 2 | Recruiting | Children's Oncology Group | 51 | 2027-05-15 | 2026-09-24 |
| Enfortumab Vedotin for the Treatment of Unresectable or Metastatic Radioiodine Refractory Differentiated Thyroid Cancer, Anaplastic Thyroid Cancer, Medullary Thyroid Cancer, or NUT Carcinoma Biopsy Procedure, Biospecimen Collection, Computed Tomography - Metastatic Differentiated Thyroid Gland Carcinoma, Metastatic NUT Carcinoma | Phase 2 | Not yet recruiting | Northwestern University | 56 | 2027-05-05 | 2026-10-07 |
| Testing an Experimental Approach to Treat Patients With Plasma Cell Leukemia, The QUANTUM Trial Autologous Hematopoietic Stem Cell Transplantation, Biospecimen Collection, Bone Marrow Aspiration - Plasma Cell Leukemia | Phase 2 | Recruiting | National Cancer Institute (NCI) | 74 | 2027-04-20 | 2026-10-26 |
| Autologous Tumor Infiltrating Lymphocytes With Interleukin-2 for the Treatment of Locally Advanced, Recurrent or Metastatic Gastrointestinal Stromal Tumors Aldesleukin, Biospecimen Collection, Chest Radiography - Locally Advanced Gastrointestinal Stromal Tumor, Metastatic Gastrointestinal Stromal Tumor | Phase 2 | Not yet recruiting | Joal Beane | 59 | 2027-02-15 | 2026-10-13 |
| SMAD4 Tailored Neoadjuvant Therapy for the Treatment of Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma, SMART-PANC Trial Biospecimen Collection, Computed Tomography, Electronic Health Record Review - Borderline Resectable Pancreatic Ductal Adenocarcinoma, Resectable Pancreatic Ductal Adenocarcinoma | Phase 2 | Not yet recruiting | Northwestern University | 125 | 2027-02-03 | 2026-08-06 |
| Testing the Addition of Ivonescimab Combined With Standard Chemotherapy Compared to the Usual Chemotherapy and Immunotherapy Treatment for Patients With Advanced Biliary Tract Cancer Biospecimen Collection, Cisplatin, Computed Tomography - Locally Advanced Biliary Tract Adenocarcinoma, Locally Advanced Extrahepatic Cholangiocarcinoma | Phase 2 / Phase 3 | Not yet recruiting | ECOG-ACRIN Cancer Research Group | 336 | 2027-01-11 | 2026-08-14 |
| Testing the Use of High Dose Testosterone Followed by Darolutamide Compared to the Usual Care for Patients With Metastatic Prostate Cancer Abiraterone Acetate, Biospecimen Collection, Bone Scan - Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 / Phase 3 | Not yet recruiting | ECOG-ACRIN Cancer Research Group | 432 | 2027-01-06 | 2026-10-01 |
| Comparing Bispecific Antibody Treatment to Autologous Stem Cell Transplant for Newly Diagnosed, Standard Risk Multiple Myeloma Daratumumab and Recombinant Human Hyaluronidase, Lenalidomide, Bortezomib - Multiple Myeloma (MM) | Phase 2 / Phase 3 | Not yet recruiting | Alliance for Clinical Trials in Oncology | 920 | 2026-12-23 | 2026-10-22 |
| Testing Repeat Radiation Therapy for Recurrent Non-small Cell Lung Cancer Biospecimen Collection, Computed Tomography, Immunotherapy - Locally Recurrent Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8 | Phase 2 | Not yet recruiting | NRG Oncology | 138 | 2026-12-18 | 2026-09-23 |
| Elacestrant With Everolimus for the Treatment of Recurrent Advanced or Metastatic ER-Positive Endometrial Cancer Biospecimen Collection, Computed Tomography, Elacestrant - Advanced Endometrial Carcinoma, Metastatic Endometrial Carcinoma | Phase 2 | Not yet recruiting | Jonsson Comprehensive Cancer Center | 50 | 2026-12-18 | 2026-06-09 |
| Non-covalent BTK Inhibitor Nemtabrutinib in Combination With the CD20 Monoclonal Antibody Rituximab for the Treatment of Marginal Zone Lymphoma Biopsy Procedure, Biospecimen Collection, Bone Marrow Biopsy - Conjunctival Mucosa-Associated Lymphoid Tissue Lymphoma, Gastric Mucosa-Associated Lymphoid Tissue Lymphoma | Phase 2 | Recruiting | City of Hope Medical Center | 35 | 2026-12-16 | 2026-09-29 |
| Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Carcinomas Biospecimen Collection, Computed Tomography, Incomplete Freund''s Adjuvant - Digestive System Neuroendocrine Neoplasm, Lung Neuroendocrine Neoplasm | Phase 2 | Not yet recruiting | Roswell Park Cancer Institute | 60 | 2026-12-15 | 2026-10-20 |
| Testing Safe Doses of Anti-Cancer Medicines, 5-Flurouracil (5-FU) and Tretinoin (ATRA), Added to the Usual Cancer Treatment of Ependymoma Biospecimen Collection, Echocardiography Test, Fluorouracil - Childhood Posterior Fossa Ependymoma | Phase 1 / Phase 2 | Not yet recruiting | Children's Oncology Group | 70 | 2026-12-11 | 2026-09-30 |
| HRX215, A First Generation MKK4 Inhibitor Drug, for the Treatment of Patients With Colorectal Liver Metastasis After Undergoing a Portal Vein Embolization Biopsy Procedure, Biospecimen Collection, Computed Tomography - Metastatic Colorectal Carcinoma, Metastatic Malignant Neoplasm in the Liver | Phase 2 | Not yet recruiting | Mayo Clinic | 80 | 2026-12-01 | 2026-10-05 |
| Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO Trial Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging - Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8 | Phase 2 | Not yet recruiting | Fred Hutchinson Cancer Center | 50 | 2026-12-01 | 2026-09-17 |
| Neoadjuvant Intravesical Nadofaragene Firadenovec With Gemcitabine, Cisplatin and Durvalumab for the Treatment of Muscle Invasive Bladder Cancer, TRIFECTA Trial Nadofaragene Firadenovec, Durvalumab, Gemcitabine - Muscle Invasive Bladder Urothelial Carcinoma, Stage II Bladder Cancer AJCC v8 | Phase 2 | Not yet recruiting | University of Washington | 33 | 2026-12-01 | 2026-10-26 |
Showing 20 of 444. Sign in to see all of them.
Prostatic Neoplasms (38) · Lung Neoplasms (29) · Carcinoma, Non-Small-Cell Lung (26) · Multiple Myeloma (22) · Breast Neoplasms (19) · Lymphoma (19) · Pancreatic Neoplasms (19) · Urinary Bladder Neoplasms (18) · Glioblastoma (17) · Glioma (16) · Neoplasm Metastasis (15) · Carcinoma, Renal Cell (14) · Melanoma (13) · Squamous Cell Carcinoma of Head and Neck (13) · Cholangiocarcinoma (12)
National Cancer Institute (NCI) (172) · Mayo Clinic (45) · University of Washington (15) · City of Hope Medical Center (13) · OHSU Knight Cancer Institute (13) · Children's Oncology Group (12) · Alliance for Clinical Trials in Oncology (11) · Emory University (9) · Fred Hutchinson Cancer Center (9) · Northwestern University (9) · SWOG Cancer Research Network (9) · NRG Oncology (8) · Roswell Park Cancer Institute (8) · ECOG-ACRIN Cancer Research Group (5) · Jonsson Comprehensive Cancer Center (5)
United States (405) · Canada (41) · Puerto Rico (28) · Australia (18) · France (7) · New Zealand (7) · Guam (4) · Hong Kong (4) · Israel (4) · South Korea (3) · Germany (2) · Ireland (2) · Japan (2) · Norway (2) · Saudi Arabia (2)
Andrei Iagaru (3) · Nilofer S Azad (3) · Patricia M LoRusso (3) · A P Chen (2) · Alain C Mita (2) · Alan L Ho (2) · Andrea B Apolo (2) · Angela Castellanos Rodriguez, MD, MSc (2) · Bhavana Konda (2) · Chad Tang (2) · Devalingam Mahalingam (2) · Funda Meric-Bernstam (2) · Haider S Mahdi (2) · Jacob J. Orme, MD, PhD (2) · Jill Barnes, PhD (2)
PMID 31401903, PMID 39571596, PMID 20819978, PMID 21194898, PMID 22571443, PMID 23419134, PMID 23574119, PMID 23810467, PMID 24224624, PMID 25024303, PMID 25218906, PMID 26586415, PMID 26659347, PMID 27185374, PMID 28223062, PMID 28245140, PMID 29223478, PMID 29748435, PMID 29902200, PMID 30125215, PMID 30227893, PMID 31478089, PMID 31969335, PMID 32109194, PMID 32125937, PMID 32463741, PMID 32483359, PMID 32600454, PMID 33048619, PMID 33067126, PMID 33084020, PMID 33303537, PMID 33362722, PMID 33591402, PMID 33602696, PMID 33604999, PMID 33882143, PMID 33927108, PMID 34331515, PMID 34380663, PMID 34406051, PMID 34432874, PMID 34470496, PMID 34486544, PMID 34552007, PMID 34607348, PMID 34716198, PMID 34717797, PMID 34783177, PMID 34907910
U10CA180820 (31), U10CA180868 (26), U10CA180821 (25), U10CA180886 (24), U10CA180888 (23), P30CA060553 (15), P30CA033572 (14), UM1CA186689 (12), UM1CA186691 (10), P30CA138292 (9), UM1CA186709 (9), UM1CA186644 (7), UM1CA186704 (7), UM1CA186686 (5), UM1CA186688 (5)