452 recruiting, 450 completed, 260 active not recruiting, 185 unknown. 444 Phase 2, 431 Not applicable, 254 Phase 1, 131 Phase 3, 36 Early Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Preoperative Durvalumab, Cisplatin, Gemcitabine With or Without Futibatinib Targeted Therapy for the Treatment of Resectable Intrahepatic Cholangiocarcinoma, OPTIC Trial Biospecimen Collection, Cisplatin, Computed Tomography - Resectable Intrahepatic Cholangiocarcinoma | Phase 2 | Not yet recruiting | Northwestern University | 44 | 2027-12-10 | 2026-06-10 |
| Technical Development of Multi-Parametric Renocerebral MRI MRI, Group 4 - Aging | Suspended | University of Minnesota | 120 | 2027-12-01 | 2026-10-14 | |
| Futibatinib With Paclitaxel and Ramucirumab for the Treatment of Locally Advanced or Unresectable Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Biospecimen Collection, Computed Tomography, Futibatinib - Clinical Stage II Esophageal Adenocarcinoma AJCC v8, Clinical Stage III Esophageal Adenocarcinoma AJCC v8 | Phase 1 | Not yet recruiting | Northwestern University | 18 | 2027-09-09 | 2026-10-20 |
| Zanubrutinib and Sonrotoclax for the Treatment of Relapsed Chronic Lymphocytic Leukemia /Small Lymphocytic Leukemia, ZeuS-2 Trial Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | Phase 2 | Not yet recruiting | City of Hope Medical Center | 44 | 2027-08-04 | 2026-09-10 |
| Multi-Parametric MRI for Renal Transplantation Magnetic Resonance Imaging - Renal Transplant Rejection | Not yet recruiting | University of Minnesota | 140 | 2027-07-01 | 2026-09-16 | |
| Testing the Addition of Iberdomide to Therapy in People With Neuroblastoma That Has Come Back, Not Responded to Treatment, or Gotten Worse Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography - Recurrent Ganglioneuroblastoma, Recurrent Neuroblastoma | Phase 1 / Phase 2 | Recruiting | National Cancer Institute (NCI) | 76 | 2027-06-25 | 2026-10-22 |
| Zipalertinib With Carboplatin and Pemetrexed for the Treatment of Resectable, Stage II-IIIB, Non-Small Cell Lung Cancer Biospecimen Collection, Carboplatin, Computed Tomography - Lung Non-Squamous Non-Small Cell Carcinoma | Phase 2 | Not yet recruiting | Jonsson Comprehensive Cancer Center | 16 | 2027-06-01 | 2026-02-05 |
| A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information Biospecimen Collection, Chest Radiography, Computed Tomography - Clinical Stage 0 Cutaneous Melanoma AJCC v8, Clinical Stage I Cutaneous Melanoma AJCC v8 | Phase 2 | Recruiting | Children's Oncology Group | 51 | 2027-05-15 | 2026-09-24 |
| CCR5 Targeting Leronlimab in Combination With Hepatic Arterial Infusion Floxuridine and Systemic Therapy for the Treatment of Colorectal Cancer Liver Metastases, CHAMP Trial Biopsy Procedure, Biospecimen Collection, Computed Tomography - Metastatic Colorectal Carcinoma, Metastatic Malignant Neoplasm in the Liver | Phase 1 | Not yet recruiting | City of Hope Medical Center | 36 | 2027-05-06 | 2026-09-25 |
| Enfortumab Vedotin for the Treatment of Unresectable or Metastatic Radioiodine Refractory Differentiated Thyroid Cancer, Anaplastic Thyroid Cancer, Medullary Thyroid Cancer, or NUT Carcinoma Biopsy Procedure, Biospecimen Collection, Computed Tomography - Metastatic Differentiated Thyroid Gland Carcinoma, Metastatic NUT Carcinoma | Phase 2 | Not yet recruiting | Northwestern University | 56 | 2027-05-05 | 2026-10-07 |
| Testing an Experimental Approach to Treat Patients With Plasma Cell Leukemia, The QUANTUM Trial Autologous Hematopoietic Stem Cell Transplantation, Biospecimen Collection, Bone Marrow Aspiration - Plasma Cell Leukemia | Phase 2 | Recruiting | National Cancer Institute (NCI) | 74 | 2027-04-20 | 2026-10-26 |
| Genetically Engineered Cells (BAFFR-CAR T Cells) for the Treatment of Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia and B-cell Lymphoblastic Lymphoma Autologous BAFFR-targeting CAR T Cells, Biospecimen Collection, Bone Marrow Aspiration - Recurrent B Acute Lymphoblastic Leukemia, Recurrent B Lymphoblastic Lymphoma | Phase 1 | Not yet recruiting | City of Hope Medical Center | 16 | 2027-04-17 | 2026-08-11 |
| Adding Surgery and Radiation to the Usual Treatment for HER2-Positive Breast Cancer That Had Already Spread at Diagnosis Biopsy Procedure, Biospecimen Collection, Breast Conservation Treatment - Anatomic Stage IV Breast Cancer AJCC v8, Metastatic HER2-Positive Breast Carcinoma | Phase 3 | Recruiting | SWOG Cancer Research Network | 562 | 2027-03-09 | 2026-10-13 |
| FPS-ZM1 With or Without Dexamethasone for Controlling Post Operative Cerebral Edema in Patients With Glioblastoma Biospecimen Collection, Computed Tomography, Dexamethasone - Glioblastoma, Malignant Glioma | Phase 1 | Not yet recruiting | City of Hope Medical Center | 24 | 2027-02-17 | 2026-08-27 |
| Autologous Tumor Infiltrating Lymphocytes With Interleukin-2 for the Treatment of Locally Advanced, Recurrent or Metastatic Gastrointestinal Stromal Tumors Aldesleukin, Biospecimen Collection, Chest Radiography - Locally Advanced Gastrointestinal Stromal Tumor, Metastatic Gastrointestinal Stromal Tumor | Phase 2 | Not yet recruiting | Joal Beane | 59 | 2027-02-15 | 2026-10-13 |
| Testing the Investigational Medication Pembrolizumab After Kidney Removal for Patients With Non-Clear Cell Renal Cell Carcinoma Biospecimen Collection, Bone Scan, Computed Tomography - Non-Clear Cell Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8 | Phase 3 | Not yet recruiting | National Cancer Institute (NCI) | 400 | 2027-02-10 | 2026-07-08 |
| SMAD4 Tailored Neoadjuvant Therapy for the Treatment of Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma, SMART-PANC Trial Biospecimen Collection, Computed Tomography, Electronic Health Record Review - Borderline Resectable Pancreatic Ductal Adenocarcinoma, Resectable Pancreatic Ductal Adenocarcinoma | Phase 2 | Not yet recruiting | Northwestern University | 125 | 2027-02-03 | 2026-08-06 |
| Testing the Addition of Ivonescimab Combined With Standard Chemotherapy Compared to the Usual Chemotherapy and Immunotherapy Treatment for Patients With Advanced Biliary Tract Cancer Biospecimen Collection, Cisplatin, Computed Tomography - Locally Advanced Biliary Tract Adenocarcinoma, Locally Advanced Extrahepatic Cholangiocarcinoma | Phase 2 / Phase 3 | Not yet recruiting | ECOG-ACRIN Cancer Research Group | 336 | 2027-01-11 | 2026-08-14 |
| Testing the Use of High Dose Testosterone Followed by Darolutamide Compared to the Usual Care for Patients With Metastatic Prostate Cancer Abiraterone Acetate, Biospecimen Collection, Bone Scan - Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 / Phase 3 | Not yet recruiting | ECOG-ACRIN Cancer Research Group | 432 | 2027-01-06 | 2026-10-01 |
| Magnetic Resonance-Guided Stereotactic Body Radiation Therapy for the Treatment of Prostate Cancer Biopsy Procedure, Computed Tomography, Electronic Health Record Review - Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8 | Not applicable | Not yet recruiting | City of Hope Medical Center | 20 | 2027-01-01 | 2026-08-17 |
Showing 20 of 1646. Sign in to see all of them.
Prostatic Neoplasms (107) · Breast Neoplasms (87) · Lung Neoplasms (59) · Brain Neoplasms (51) · Glioblastoma (47) · Neoplasm Metastasis (43) · Pancreatic Neoplasms (43) · Carcinoma, Non-Small-Cell Lung (42) · Glioma (42) · Multiple Myeloma (33) · Urinary Bladder Neoplasms (32) · Carcinoma, Renal Cell (31) · Carcinoma, Hepatocellular (29) · Ovarian Neoplasms (29) · Melanoma (28)
National Cancer Institute (NCI) (263) · Mayo Clinic (95) · City of Hope Medical Center (46) · M.D. Anderson Cancer Center (45) · Assiut University (37) · Children's Oncology Group (28) · NRG Oncology (25) · University of Wisconsin, Madison (24) · Jonsson Comprehensive Cancer Center (21) · Memorial Sloan Kettering Cancer Center (20) · Alliance for Clinical Trials in Oncology (19) · Hospices Civils de Lyon (19) · OHSU Knight Cancer Institute (19) · University of Washington (19) · Northwestern University (18)
United States (1056) · France (200) · Canada (119) · Puerto Rico (51) · United Kingdom (48) · Australia (35) · China (29) · Switzerland (24) · Germany (20) · Belgium (19) · Egypt (18) · Netherlands (18) · Denmark (17) · Israel (17) · Italy (17)
Jill N Barnes, PhD (6) · Andrea B Apolo (4) · Andrei Iagaru (4) · Haider S Mahdi (4) · Joyce F Liu (4) · Rahul Aggarwal, MD (4) · Roman O. Kowalchuk, MD (4) · Terence C. Burns, MD, PhD (4) · A P Chen (3) · Behnam Badie (3) · Funda Meric-Bernstam (3) · Ibrahim Aldoss (3) · Jacob J. Orme, MD, PhD (3) · Marwan G Fakih (3) · Matthew S. Block, MD, PhD (3)
PMID 37505794, PMID 26679193, PMID 27939583, PMID 28674168, PMID 31401903, PMID 33395032, PMID 34604088, PMID 35031545, PMID 37185961, PMID 37222189, PMID 37676209, PMID 38421243, PMID 39571596, PMID 41747891, PMID 10561087, PMID 10625901, PMID 10648324, PMID 10700504, PMID 11039681, PMID 11062288, PMID 11270700, PMID 11371752, PMID 11427137, PMID 11459743, PMID 11641580, PMID 11704359, PMID 12236201, PMID 12660385, PMID 12691631, PMID 12736767, PMID 15589017, PMID 15618060, PMID 15800226, PMID 15890993, PMID 15944094, PMID 16620352, PMID 16885176, PMID 16955381, PMID 1732966, PMID 17362687, PMID 17392300, PMID 17409371, PMID 17962606, PMID 18256991, PMID 18662894, PMID 19170709, PMID 19252779, PMID 19344074, PMID 19448188, PMID 19807850
U10CA180868 (48), P30CA033572 (47), U10CA180820 (46), U10CA180886 (42), U10CA180821 (34), U10CA180888 (33), P30CA060553 (22), UM1CA186689 (15), UM1CA186709 (15), P30CA138292 (14), UM1CA186691 (12), P30CA014089 (11), UM1CA186644 (10), UM1CA186690 (10), UM1CA186712 (10)