Mitomycin c: Clinical Trials

16 trials of Mitomycin c, newest first

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16 completed. 16 Phase 3, 3 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 316Completed 16
Phase 23Completed 3

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Trials (filtered) newest first · largest first

All 16 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Intralesional Injection of Mitomycin C Following Visual Internal Urethrotomy for Recurrent Urethral Stricture
Mitomycin c - Urethral Stricture
Phase 2 / Phase 3CompletedAin Shams University502022-01-012024-01-30
The Bladder Instillation Comparison Study
Mitomycin C, Gemcitabine - Urinary Bladder Neoplasms
Phase 3CompletedCorewell Health West1012016-04-192023-04-21
Mitomicin C for Prevention Postoperative Endoscopic Sinus Surgery Synechia and QOL in Chronic Rhinosinusitis
Mitomicin C, Identical placebo solution - Chronic Rhinosinusitis, Postoperative Nasal Synerchia
Phase 3CompletedMahidol University2242015-03-012018-05-23
Bevacizumab Versus Mitomycin C as Trabeculectomy Adjuvant in Uncontrolled Glaucoma
Standard Guarded Trabeculectomy, Mitomycin C, Bevacizumab - Glaucoma
Phase 2 / Phase 3CompletedAthens Vision Eye Institute402014-01-012016-09-15
Results of Adjunctive Intraoperative Bevacizumab Injection on Trabeculectomy Outcome
Bevacizumab, Mitomycin C - Glaucoma
Phase 2 / Phase 3CompletedPrince of Songkla University392010-12-012014-01-31
Chemoembolization With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery
Cisplatin, Computed Tomography, Doxorubicin Hydrochloride - Hepatocellular Carcinoma, Unresectable Hepatocellular Carcinoma
Phase 3CompletedNational Cancer Institute (NCI)2352009-10-282024-01-03
Ologen (OculusGen)-Glaucoma MMC Control in Pakistan
ologen collagen matrix in glaucoma filtering surgery, MMC in glaucoma filtering surgery - Glaucoma, Trabeculectomy
Phase 3CompletedPro Top & Mediking Company Limited402007-03-012011-10-07
Active Symptom Control With or Without Chemotherapy in Treating Patients With Malignant Pleural Mesothelioma
cisplatin, mitomycin C, vincristine sulfate - Malignant Mesothelioma
Phase 3CompletedMedical Research Council8402003-09-012013-08-07
Radiation Therapy With or Without Chemotherapy in Treating Patients With Stage II or Stage III Bladder Cancer
fluorouracil, mitomycin C, radiation therapy - Bladder Cancer
Phase 3CompletedUniversity Hospital Birmingham3502001-06-012013-12-18
Radiation Therapy Plus Fluorouracil With or Without Additional Chemotherapy in Treating Patients With Primary Anal Cancer
cisplatin, fluorouracil, mitomycin C - Anal Cancer
Phase 3CompletedUniversity College London (UCL) Cancer Institute6002001-03-012013-08-26
Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer
cisplatin, fluorouracil, mitomycin C - Anal Cancer
Phase 3CompletedRadiation Therapy Oncology Group6821998-10-012017-01-04
Adjuvant Chemotherapy Plus Radiation Therapy in Treating Women With Early-Stage Breast Cancer
CMF regimen, cyclophosphamide, doxorubicin hydrochloride - Breast Cancer
Phase 3CompletedUniversity Hospital Birmingham22501998-07-012013-12-19
Radiation Therapy With or Without Chemotherapy After Surgery in Treating Patients With Stage IB or Stage IIA Cervical Cancer
bleomycin sulfate, cisplatin, fluorouracil - Cervical Cancer
Phase 3CompletedEuropean Organisation for Research and Treatment of Cancer - EORTC7001997-12-012012-07-11
Surgery With or Without Preoperative Chemotherapy in Treating Patients With Resectable Non-small Cell Lung Cancer
carboplatin, cisplatin, docetaxel - Lung Cancer
Phase 3CompletedMedical Research Council6001997-08-012013-12-04
Radiation Therapy and Chemotherapy in Treating Patients With Head and Neck Cancer
mitomycin C, porfiromycin, brachytherapy - Carcinoma of Unknown Primary, Head and Neck Cancer
Phase 3CompletedYale University1992-11-012013-07-25
Radiation Therapy, Chemotherapy, or Observation in Treating Patients With Bladder Cancer
BCG vaccine, mitomycin C, radiation therapy - Bladder Cancer
Phase 3CompletedMedical Research Council1991-09-012013-12-18

Conditions studied

Glaucoma (3)  ·  Urinary Bladder Neoplasms (3)  ·  Anal Canal Carcinoma (2)  ·  Anus Neoplasms (2)  ·  Breast Neoplasms (1)  ·  Carcinoma, Hepatocellular (1)  ·  Carcinoma, Non-Small-Cell Lung (1)  ·  Head and Neck Neoplasms (1)  ·  Lung Neoplasms (1)  ·  Mesothelioma, Malignant (1)  ·  Neoplasms, Unknown Primary (1)  ·  Non-Muscle Invasive Bladder Neoplasms (1)  ·  Squamous Cell Carcinoma of Head and Neck (1)  ·  Urethral Stricture (1)  ·  Uterine Cervical Neoplasms (1)

Sponsors

Medical Research Council (3)  ·  University Hospital Birmingham (2)  ·  Ain Shams University (1)  ·  Athens Vision Eye Institute (1)  ·  Corewell Health West (1)  ·  European Organisation for Research and Treatment of Cancer - EORTC (1)  ·  Mahidol University (1)  ·  National Cancer Institute (NCI) (1)  ·  Prince of Songkla University (1)  ·  Pro Top & Mediking Company Limited (1)  ·  Radiation Therapy Oncology Group (1)  ·  University College London (UCL) Cancer Institute (1)  ·  Yale University (1)

Countries

United Kingdom (7)  ·  United States (4)  ·  Thailand (2)  ·  Egypt (1)  ·  Pakistan (1)  ·  South Africa (1)

Top investigators

Adrian Hodson (1)  ·  Al B Benson (1)  ·  Al B. Benson, MD, FACP (1)  ·  Brian R Lane, MD (1)  ·  Gerassimos Kopsinis, M.D., Ph.D. (1)  ·  Ian E. Smith, MD (1)  ·  Indy Fernando, MD (1)  ·  Jaffer A. Ajani, MD (1)  ·  James J. Fischer, MD, PhD (1)  ·  Jan B. Vermorken, MD, PhD (1)  ·  Joel E. Tepper, MD (1)  ·  John S. MacDonald, MD (1)  ·  Martin F. Muers, MD (1)  ·  Michael G. Haddock, MD (1)  ·  Nicholas D. James, MD (1)

Results publications

PMID 10937547, PMID 17122118, PMID 17544497, PMID 18430910, PMID 18486741, PMID 19139424, PMID 20564111, PMID 22512481, PMID 23150707, PMID 31785830, PMID 33539743, PMID 34125951, PMID 36912740, PMID 37012180

NIH funding

U10CA021115 (1), U10CA180820 (1)