16 completed. 16 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 16 | Completed 16 |
| Phase 2 | 3 | Completed 3 |
Follow Mitomycin c: new trials by email Literature Review of Mitomycin c trials Research Report on Mitomycin c
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intralesional Injection of Mitomycin C Following Visual Internal Urethrotomy for Recurrent Urethral Stricture Mitomycin c - Urethral Stricture | Phase 2 / Phase 3 | Completed | Ain Shams University | 50 | 2022-01-01 | 2024-01-30 |
| The Bladder Instillation Comparison Study Mitomycin C, Gemcitabine - Urinary Bladder Neoplasms | Phase 3 | Completed | Corewell Health West | 101 | 2016-04-19 | 2023-04-21 |
| Mitomicin C for Prevention Postoperative Endoscopic Sinus Surgery Synechia and QOL in Chronic Rhinosinusitis Mitomicin C, Identical placebo solution - Chronic Rhinosinusitis, Postoperative Nasal Synerchia | Phase 3 | Completed | Mahidol University | 224 | 2015-03-01 | 2018-05-23 |
| Bevacizumab Versus Mitomycin C as Trabeculectomy Adjuvant in Uncontrolled Glaucoma Standard Guarded Trabeculectomy, Mitomycin C, Bevacizumab - Glaucoma | Phase 2 / Phase 3 | Completed | Athens Vision Eye Institute | 40 | 2014-01-01 | 2016-09-15 |
| Results of Adjunctive Intraoperative Bevacizumab Injection on Trabeculectomy Outcome Bevacizumab, Mitomycin C - Glaucoma | Phase 2 / Phase 3 | Completed | Prince of Songkla University | 39 | 2010-12-01 | 2014-01-31 |
| Chemoembolization With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery Cisplatin, Computed Tomography, Doxorubicin Hydrochloride - Hepatocellular Carcinoma, Unresectable Hepatocellular Carcinoma | Phase 3 | Completed | National Cancer Institute (NCI) | 235 | 2009-10-28 | 2024-01-03 |
| Ologen (OculusGen)-Glaucoma MMC Control in Pakistan ologen collagen matrix in glaucoma filtering surgery, MMC in glaucoma filtering surgery - Glaucoma, Trabeculectomy | Phase 3 | Completed | Pro Top & Mediking Company Limited | 40 | 2007-03-01 | 2011-10-07 |
| Active Symptom Control With or Without Chemotherapy in Treating Patients With Malignant Pleural Mesothelioma cisplatin, mitomycin C, vincristine sulfate - Malignant Mesothelioma | Phase 3 | Completed | Medical Research Council | 840 | 2003-09-01 | 2013-08-07 |
| Radiation Therapy With or Without Chemotherapy in Treating Patients With Stage II or Stage III Bladder Cancer fluorouracil, mitomycin C, radiation therapy - Bladder Cancer | Phase 3 | Completed | University Hospital Birmingham | 350 | 2001-06-01 | 2013-12-18 |
| Radiation Therapy Plus Fluorouracil With or Without Additional Chemotherapy in Treating Patients With Primary Anal Cancer cisplatin, fluorouracil, mitomycin C - Anal Cancer | Phase 3 | Completed | University College London (UCL) Cancer Institute | 600 | 2001-03-01 | 2013-08-26 |
| Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer cisplatin, fluorouracil, mitomycin C - Anal Cancer | Phase 3 | Completed | Radiation Therapy Oncology Group | 682 | 1998-10-01 | 2017-01-04 |
| Adjuvant Chemotherapy Plus Radiation Therapy in Treating Women With Early-Stage Breast Cancer CMF regimen, cyclophosphamide, doxorubicin hydrochloride - Breast Cancer | Phase 3 | Completed | University Hospital Birmingham | 2250 | 1998-07-01 | 2013-12-19 |
| Radiation Therapy With or Without Chemotherapy After Surgery in Treating Patients With Stage IB or Stage IIA Cervical Cancer bleomycin sulfate, cisplatin, fluorouracil - Cervical Cancer | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 700 | 1997-12-01 | 2012-07-11 |
| Surgery With or Without Preoperative Chemotherapy in Treating Patients With Resectable Non-small Cell Lung Cancer carboplatin, cisplatin, docetaxel - Lung Cancer | Phase 3 | Completed | Medical Research Council | 600 | 1997-08-01 | 2013-12-04 |
| Radiation Therapy and Chemotherapy in Treating Patients With Head and Neck Cancer mitomycin C, porfiromycin, brachytherapy - Carcinoma of Unknown Primary, Head and Neck Cancer | Phase 3 | Completed | Yale University | 1992-11-01 | 2013-07-25 | |
| Radiation Therapy, Chemotherapy, or Observation in Treating Patients With Bladder Cancer BCG vaccine, mitomycin C, radiation therapy - Bladder Cancer | Phase 3 | Completed | Medical Research Council | 1991-09-01 | 2013-12-18 |
Glaucoma (3) · Urinary Bladder Neoplasms (3) · Anal Canal Carcinoma (2) · Anus Neoplasms (2) · Breast Neoplasms (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Non-Small-Cell Lung (1) · Head and Neck Neoplasms (1) · Lung Neoplasms (1) · Mesothelioma, Malignant (1) · Neoplasms, Unknown Primary (1) · Non-Muscle Invasive Bladder Neoplasms (1) · Squamous Cell Carcinoma of Head and Neck (1) · Urethral Stricture (1) · Uterine Cervical Neoplasms (1)
Medical Research Council (3) · University Hospital Birmingham (2) · Ain Shams University (1) · Athens Vision Eye Institute (1) · Corewell Health West (1) · European Organisation for Research and Treatment of Cancer - EORTC (1) · Mahidol University (1) · National Cancer Institute (NCI) (1) · Prince of Songkla University (1) · Pro Top & Mediking Company Limited (1) · Radiation Therapy Oncology Group (1) · University College London (UCL) Cancer Institute (1) · Yale University (1)
United Kingdom (7) · United States (4) · Thailand (2) · Egypt (1) · Pakistan (1) · South Africa (1)
Adrian Hodson (1) · Al B Benson (1) · Al B. Benson, MD, FACP (1) · Brian R Lane, MD (1) · Gerassimos Kopsinis, M.D., Ph.D. (1) · Ian E. Smith, MD (1) · Indy Fernando, MD (1) · Jaffer A. Ajani, MD (1) · James J. Fischer, MD, PhD (1) · Jan B. Vermorken, MD, PhD (1) · Joel E. Tepper, MD (1) · John S. MacDonald, MD (1) · Martin F. Muers, MD (1) · Michael G. Haddock, MD (1) · Nicholas D. James, MD (1)
PMID 10937547, PMID 17122118, PMID 17544497, PMID 18430910, PMID 18486741, PMID 19139424, PMID 20564111, PMID 22512481, PMID 23150707, PMID 31785830, PMID 33539743, PMID 34125951, PMID 36912740, PMID 37012180
U10CA021115 (1), U10CA180820 (1)