16 completed. 16 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 16 | Completed 16 |
| Phase 2 | 4 | Completed 4 |
Follow Mitomycin: new trials by email Literature Review of Mitomycin trials Research Report on Mitomycin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison Between Topical Mitomycin C and Cyclosporine Mitomycin c - Pterygium | Phase 1 | Completed | Egymedicalpedia | 57 | 2021-01-01 | 2023-10-17 |
| Chemoembolization for Lung Tumors Chemoembolization, Mitomycin C, Lipiodol - Lung Metastases, Endobronchial Metastases | Phase 1 | Completed | Memorial Sloan Kettering Cancer Center | 10 | 2019-12-13 | 2025-05-16 |
| Study of Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive Cytology Dexamethasone, Diphenhydramine, Famotidine - Diseases of Oesophagus Stomach and Duodenum | Phase 1 | Completed | M.D. Anderson Cancer Center | 29 | 2017-10-27 | 2023-04-21 |
| CAVATAK (CVA21) in Non-muscle Invasive Bladder Cancer (VLA-012 CANON) CVA21, Mitomycin C - Non-muscle Invasive Bladder Cancer | Phase 1 | Completed | Viralytics | 16 | 2015-01-16 | 2022-07-27 |
| Phase I Study of Cetuximab in Combination With 5-fluoruracil, Mitomycin C and Radiotherapy in Patients With Anal Cancer Stage T2 (>4 cm) - T4 N0-3 M0 or Any T N2-3 M0 Cetuximab, Mitomycin C, 5-Fluoruracil - Locally Advanced Cancer in the Anal Region | Phase 1 | Completed | Lund University Hospital | 21 | 2012-06-01 | 2020-02-28 |
| Phase I Mitomycin Combined With Bacillus Calmette-Guérin (BCG) for Bladder Cancer Mitomycin C - Urinary Bladder Neoplasm | Phase 1 | Completed | The University of Texas Health Science Center at San Antonio | 18 | 2012-03-01 | 2015-12-03 |
| Trial of ICM With or Without AZD2281 (Olaparib) in Patients With Advanced Pancreatic Cancer Irinotecan, Cisplatin, Olaparib (for levels 1 and 5) - Pancreatic Cancer | Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 18 | 2011-01-01 | 2016-03-22 |
| Veliparib With or Without Mitomycin C in Treating Patients With Metastatic, Unresectable, or Recurrent Solid Tumors Laboratory Biomarker Analysis, Mitomycin, Veliparib - Solid Neoplasm | Phase 1 | Completed | National Cancer Institute (NCI) | 20 | 2009-10-01 | 2016-07-11 |
| Sorafenib Tosylate and Chemoembolization in Treating Patients With Unresectable Liver Cancer sorafenib tosylate, doxorubicin hydrochloride, cisplatin - Hepatocellular Carcinoma, Liver Cancer | Phase 1 | Completed | Abramson Cancer Center at Penn Medicine | 18 | 2009-09-01 | 2013-02-26 |
| Sorafenib Tosylate and Chemoembolization With Doxorubicin Hydrochloride and Mitomycin in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery doxorubicin hydrochloride, mitomycin C, sorafenib tosylate - Liver Cancer | Phase 1 | Completed | UNC Lineberger Comprehensive Cancer Center | 11 | 2009-07-22 | 2018-01-05 |
| Use of Ranibizumab With Mitomycin C During Trabeculectomy Ranibizumab, Ranibizumab and MMC, MMC - Glaucoma | Phase 1 / Phase 2 | Completed | University of Colorado, Denver | 30 | 2008-04-01 | 2016-10-13 |
| Safety Study of Recombinant Human Hyaluronidase (Chemophase) in Combination With Mitomycin in Participants With Superficial Bladder Cancer Mitomycin C, Chemophase - Bladder Cancer | Phase 1 / Phase 2 | Completed | Halozyme Therapeutics | 27 | 2006-03-30 | 2021-10-29 |
| Adjuvant HIPEC to Prevent Colorectal Peritoneal Metastases in High-risk Patients adjuvant HIPEC, surgery - Colorectal Neoplasm, Metastasis | Phase 1 / Phase 2 | Completed | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | 20 | 2006-01-01 | 2015-10-15 |
| Study With Mitomycin c/5-FU/FA in Pretreated Gastrointestinal Cancer Patients With Metastases (>= Second-line Treatment) Mitomycin C, 5-FU, Folinic acid - Gastrointestinal Neoplasms, Neoplasm Metastasis | Phase 1 / Phase 2 | Completed | University Hospital Tuebingen | 1999-09-01 | 2013-01-28 | |
| Irinotecan Plus Mitomycin in Treating Patients With Advanced Solid Tumors irinotecan hydrochloride, mitomycin C - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | The University of Texas Health Science Center at San Antonio | 12 | 1998-08-01 | 2012-08-09 |
| Mitomycin and Mitoxantrone in Treating Patients With Acute Myelogenous Leukemia sargramostim, mitomycin C, mitoxantrone hydrochloride - Leukemia | Phase 1 | Completed | Dartmouth-Hitchcock Medical Center | 29 | 1996-09-01 | 2018-03-19 |
Urinary Bladder Neoplasms (3) · Carcinoma, Hepatocellular (2) · Liver Neoplasms (2) · Neoplasm Metastasis (2) · Non-Muscle Invasive Bladder Neoplasms (2) · Anus Neoplasms (1) · Colorectal Neoplasms (1) · Gastrointestinal Neoplasms (1) · Glaucoma (1) · Leukemia (1) · Leukemia, Myeloid, Acute (1) · Pancreatic Neoplasms (1) · Pterygium (1) · Stomach Neoplasms (1)
The University of Texas Health Science Center at San Antonio (2) · Abramson Cancer Center at Penn Medicine (1) · Dartmouth-Hitchcock Medical Center (1) · Egymedicalpedia (1) · Fondazione IRCCS Istituto Nazionale dei Tumori, Milano (1) · Halozyme Therapeutics (1) · Lund University Hospital (1) · M.D. Anderson Cancer Center (1) · Memorial Sloan Kettering Cancer Center (1) · National Cancer Institute (NCI) (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1) · UNC Lineberger Comprehensive Cancer Center (1) · University Hospital Tuebingen (1) · University of Colorado, Denver (1) · Viralytics (1)
United States (11) · Egypt (1) · Norway (1) · Sweden (1) · United Kingdom (1)
Anders Johnsson, MD, PhD (1) · Brian D. Badgwell, MD (1) · Carsten Bokemeyer, MD (1) · Christopher H. Lowrey, MD (1) · Hanna H. Sanoff, MD (1) · Hardev Pandha (1) · Joerg T Hartmann, MD (1) · Malik Y. Kahook, MD (1) · Marcello Deraco, MD (1) · Marwa Zaki, Assist.Prof. (1) · Michael Goggins, MD (1) · Michael Soulen (1) · Robert S. Svatek, MD, MSCI (1) · Ronald L. Drengler, MD (1) · Sameh Mikhail (1)
PMID 20570237, PMID 24362862, PMID 26597443, PMID 27519353, PMID 28454122, PMID 31273010
2014 (1), N01CM00070 (1), N01CM62207 (1), P30CA016058 (1), P30CA016086 (1), P30CA023108 (1), P30CA054174 (1), RC2CA148346-01 (1)