16 completed, 5 recruiting, 4 unknown, 2 terminated. 29 Phase 1, 9 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 29 | Completed 16, Recruiting 5, Unknown 4, Terminated 2, Active not recruiting 1, Not yet recruiting 1 |
| Phase 2 | 9 | Completed 4, Recruiting 2, Unknown 2, Terminated 1 |
Follow Mitomycin: new trials by email Literature Review of Mitomycin trials Research Report on Mitomycin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Efficacy of PIPAC Using Single Agent Mitomycin in Solid Tumors Mitomycin C (MMC), Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC) - Peritoneal Carcinomatosis | Phase 1 | Recruiting | H. Lee Moffitt Cancer Center and Research Institute | 24 | 2026-08-05 | 2026-09-16 |
| In-home Intravesical Chemotherapy for the Treatment of Bladder Cancer, INVITE Trial BCG Solution, Cystoscopy, Docetaxel - Non-Muscle Invasive Bladder Carcinoma, Stage 0a Bladder Cancer AJCC v8 | Phase 1 / Phase 2 | Recruiting | Mayo Clinic | 40 | 2025-04-21 | 2026-10-08 |
| Intravesical Mitomycin C After Diagnostic Ureteroscopy for Upper Tract Urothelial Carcinoma Mitomycin C - Urothelial Carcinoma Ureter, Urothelial Cancer of Renal Pelvis | Phase 1 | Not yet recruiting | McMaster University | 40 | 2023-09-01 | 2023-08-07 |
| Clinical Study of Curcumin in Preventing Postoperative Adhesion of Bilateral Vocal Cords Curcumin, Mitomycin-C - Glottic Web of Larynx, Laryngeal Stenosis | Phase 1 / Phase 2 | Recruiting | Eye & ENT Hospital of Fudan University | 100 | 2023-05-05 | 2023-05-06 |
| Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies Sodium Thiosulfate, 5-Fluorouracil, Oxaliplatin - Peritoneal Mesothelioma, Peritoneal Carcinomatosis | Phase 1 | Recruiting | National Cancer Institute (NCI) | 60 | 2021-10-19 | 2026-11-12 |
| Comparison Between Topical Mitomycin C and Cyclosporine Mitomycin c - Pterygium | Phase 1 | Completed | Egymedicalpedia | 57 | 2021-01-01 | 2023-10-17 |
| Phase 1b/II Trial of Pembrolizumab Plus IMRT in Stage III/IV Carcinoma of Anus Pembrolizumab - Anal Cancer Stage III A, Anal Cancer Stage III B | Phase 1 | Active not recruiting | Cardiff University | 52 | 2020-10-19 | 2025-08-05 |
| PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer Biopsy, Cisplatin, Doxorubicin - Clinical Stage IV Gastric Cancer AJCC v8, Clinical Stage IVA Gastric Cancer AJCC v8 | Phase 1 | Recruiting | City of Hope Medical Center | 49 | 2020-08-21 | 2026-08-26 |
| Chemoembolization for Lung Tumors Chemoembolization, Mitomycin C, Lipiodol - Lung Metastases, Endobronchial Metastases | Phase 1 | Completed | Memorial Sloan Kettering Cancer Center | 10 | 2019-12-13 | 2025-05-16 |
| Decorin in Sub Scleral Trabeculectomy Decorin, Mitomycin c - Primary Open-angle Glaucoma | Phase 1 | Unknown | Cairo University | 52 | 2019-09-01 | 2019-04-23 |
| A Study of Mitomycin-c/ Capecitabine ChemoRadiotherapy Combined With Nivolumab Monotherapy or Ipilumimab and Nivolumab, as Bladder Sparing Curative Treatment for Muscle Invasive Bladder Cancer: the CRIMI Study nivolumab 480mg, nivolumab 3mg/kg, ipilimumab 1mg/kg, nivolumab 1mg/kg, ipilimumab 3mg/kg - Urinary Bladder Cancer, Invasive Bladder Cancer | Phase 1 / Phase 2 | Unknown | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 50 | 2019-01-07 | 2022-08-12 |
| Study of Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive Cytology Dexamethasone, Diphenhydramine, Famotidine - Diseases of Oesophagus Stomach and Duodenum | Phase 1 | Completed | M.D. Anderson Cancer Center | 29 | 2017-10-27 | 2023-04-21 |
| Immunotherapy Using Precision T Cells Specific to Multiple Common Tumor-Associated Antigen Combined With Transcatheter Arterial Chemoembolization for the Treatment of Advanced Hepatocellular Carcinoma TACE, Dendritic Cell, lipiodol - Recurrence Hepatocellular Carcinoma, Advanced Hepatocellular Carcinoma | Phase 1 / Phase 2 | Unknown | Second Military Medical University | 60 | 2015-09-01 | 2016-01-01 |
| CAVATAK (CVA21) in Non-muscle Invasive Bladder Cancer (VLA-012 CANON) CVA21, Mitomycin C - Non-muscle Invasive Bladder Cancer | Phase 1 | Completed | Viralytics | 16 | 2015-01-16 | 2022-07-27 |
| A Phase I/II Evaluation of ADXS11-001, Mitomycin, 5-fluorouracil (5-FU) and IMRT for Anal Cancer Treatment, 5FU, Mitomycin - Anal Cancer | Phase 1 / Phase 2 | Terminated | Brown University | 11 | 2013-02-01 | 2020-02-17 |
| Phase I Study of Cetuximab in Combination With 5-fluoruracil, Mitomycin C and Radiotherapy in Patients With Anal Cancer Stage T2 (>4 cm) - T4 N0-3 M0 or Any T N2-3 M0 Cetuximab, Mitomycin C, 5-Fluoruracil - Locally Advanced Cancer in the Anal Region | Phase 1 | Completed | Lund University Hospital | 21 | 2012-06-01 | 2020-02-28 |
| Phase I Mitomycin Combined With Bacillus Calmette-Guérin (BCG) for Bladder Cancer Mitomycin C - Urinary Bladder Neoplasm | Phase 1 | Completed | The University of Texas Health Science Center at San Antonio | 18 | 2012-03-01 | 2015-12-03 |
| Topical MTS-01 for Dermatitis During Radiation and Chemotherapy for Anal Cancer Tempol, 5-Fluorouracil, Mitomycin-C - Anal Cancer | Phase 1 | Terminated | National Cancer Institute (NCI) | 6 | 2011-03-18 | 2021-11-23 |
| Trial of ICM With or Without AZD2281 (Olaparib) in Patients With Advanced Pancreatic Cancer Irinotecan, Cisplatin, Olaparib (for levels 1 and 5) - Pancreatic Cancer | Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 18 | 2011-01-01 | 2016-03-22 |
| Veliparib With or Without Mitomycin C in Treating Patients With Metastatic, Unresectable, or Recurrent Solid Tumors Laboratory Biomarker Analysis, Mitomycin, Veliparib - Solid Neoplasm | Phase 1 | Completed | National Cancer Institute (NCI) | 20 | 2009-10-01 | 2016-07-11 |
Showing 20 of 29. Sign in to see all of them.
Urinary Bladder Neoplasms (5) · Anus Neoplasms (4) · Colorectal Neoplasms (4) · Appendiceal Neoplasms (3) · Neoplasm Metastasis (3) · Non-Muscle Invasive Bladder Neoplasms (3) · Peritoneal Neoplasms (3) · Carcinoma, Hepatocellular (2) · Gastrointestinal Neoplasms (2) · Glaucoma (2) · Liver Neoplasms (2) · Ovarian Neoplasms (2) · Stomach Neoplasms (2) · Dermatitis (1) · Glaucoma, Open-Angle (1)
National Cancer Institute (NCI) (3) · The University of Texas Health Science Center at San Antonio (2) · Abramson Cancer Center at Penn Medicine (1) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Brown University (1) · Cairo University (1) · Cardiff University (1) · City of Hope Medical Center (1) · Dartmouth-Hitchcock Medical Center (1) · Egymedicalpedia (1) · Eye & ENT Hospital of Fudan University (1) · Fondazione IRCCS Istituto Nazionale dei Tumori, Milano (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Halozyme Therapeutics (1) · Lund University Hospital (1)
United States (17) · China (2) · Egypt (2) · Norway (2) · United Kingdom (2) · Iran (1) · Netherlands (1) · Sweden (1)
Adriaan D. Bins, MD PhD (1) · Anders Johnsson, MD, PhD (1) · Andrew M Blakely, M.D. (1) · Brian D. Badgwell, MD (1) · Carsten Bokemeyer, MD (1) · Christopher H. Lowrey, MD (1) · Deborah E Citrin, M.D. (1) · Feng Shen, PHD (1) · Hanna H. Sanoff, MD (1) · Hardev Pandha (1) · Howard Safran, MD (1) · Joerg T Hartmann, MD (1) · Malik Y. Kahook, MD (1) · Marcello Deraco, MD (1) · Mark Harrison, Dr (1)
PMID 20570237, PMID 24362862, PMID 26597443, PMID 27519353, PMID 28454122, PMID 31273010
2014 (1), N01CM00070 (1), N01CM62207 (1), P30CA016058 (1), P30CA016086 (1), P30CA023108 (1), P30CA033572 (1), P30CA054174 (1), RC2CA148346-01 (1), UL1TR002377 (1)