7 completed. 7 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 7 |
Follow Microfracture: new trials by email Literature Review of Microfracture trials Research Report on Microfracture
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Allogenic Stem Cell Product(CARTISTEM®) for Osteochondral Lesion of Talus CARTISTEM®, Microfracture - Chondral or Osteochondral Lesion of Talus | Phase 3 | Completed | Hyundai Bioland Co., Ltd. | 102 | 2020-03-03 | 2022-11-29 |
| Phase III Study to Evaluate Safety and Effectiveness of NOVOCART 3D Plus vs. Microfracture in Knee Cartilage Defects NOVOCART® 3D plus, Microfracture - Traumatic Articular Cartilage Defects in the Knee Joint | Phase 3 | Completed | Tetec AG | 263 | 2013-05-01 | 2023-11-24 |
| Follow-Up Study of CARTISTEM® Versus Microfracture for the Treatment of Knee Articular Cartilage Injury or Defect CARTISTEM, Microfracture - Degenerative Osteoarthritis, Defect of Articular Cartilage | Phase 3 | Completed | Medipost Co Ltd. | 103 | 2012-06-01 | 2017-04-20 |
| Efficacy and Safety Study of co.Don Chondrosphere to Treat Cartilage Defects co.don chondrosphere®, Microfracture - Articular Cartilage Lesion of the Femoral Condyle | Phase 3 | Completed | co.don AG | 102 | 2010-10-01 | 2021-01-27 |
| Superiority of MACI® Versus Microfracture Treatment in Patients With Symptomatic Articular Cartilage Defects in the Knee autologous cultured chondrocytes on porcine collagen membrane, Microfracture - Articular Cartilage Defect | Phase 3 | Completed | Vericel Corporation | 144 | 2008-07-01 | 2021-05-12 |
| A Randomized Controlled Trial Comparing Chondro-Gide® to Microfracture Alone for Treatment of Knee Cartilage Defects. Microfracture, Chondro-Gide sutured, Chondro-Gide glued - Cartilage Injury, Osteochondritis Dissecans | Phase 3 | Completed | Geistlich Pharma AG | 67 | 2003-12-01 | 2017-02-23 |
| RCT of ChondroCelect® (in an ACI Procedure) vs Microfracture in the Repair of Cartilage Defects of the Knee ChondroCelect implantation, Microfracture - Articular Cartilage Lesion of the Femoral Condyle | Phase 3 | Completed | TiGenix n.v. | 118 | 2002-02-01 | 2011-09-26 |
Fractures, Stress (2) · Joint Diseases (1) · Osteoarthritis (1) · Osteochondritis Dissecans (1)
Geistlich Pharma AG (1) · Hyundai Bioland Co., Ltd. (1) · Medipost Co Ltd. (1) · Tetec AG (1) · TiGenix n.v. (1) · Vericel Corporation (1) · co.don AG (1)
Germany (4) · Poland (3) · Czechia (2) · France (2) · Netherlands (2) · South Korea (2) · United Kingdom (2) · Austria (1) · Belgium (1) · Croatia (1) · Hungary (1) · Latvia (1) · Lithuania (1) · Norway (1) · Sweden (1)
Beom-gu Lee, MD, PhD (1) · Choong-hyuk Choi, MD, PhD (1) · Chul-won Ha, MD, PhD (1) · Frank P Luyten, M.D., Ph.D. (1) · Hong-chul Lim, MD, PhD (1) · Hwa-jae Jeong, MD, PhD (1) · Jae-doo Yoo, MD, PhD (1) · Johan Vanlauwe, M.D. (1) · Jong-hyeok Choi, MD, PhD (1) · Jung-ro Yoon, MD, PhD (1) · Myung-ku Kim, MD, PhD (1) · Peter Angele, Prof. (1) · Seong-il Bin, MD, PhD (1)
PMID 18202295, PMID 19846694, PMID 23730377, PMID 24714783, PMID 28108777, PMID 31317047, PMID 31893951, PMID 33490296, PMID 38501741, PMID 38630297, PMID 40778441
2009 (1)