2 unknown, 1 completed, 1 not yet recruiting, 1 recruiting. 3 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 1, Unknown 1, Withdrawn 1 |
Follow Methylation: new trials by email Literature Review of Methylation trials Research Report on Methylation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ctDNA Mutations and Methylation Status for Early Detection of Lung Cancer in Patients With Suspicious Lung Nodules ctDNA mutations and methylation with SPOTMAS Lung assays, Non-contrast LDCT Thorax scans - Lung Nodules, Lung Cancer Screening | Not yet recruiting | The University of Hong Kong | 200 | 2026-06-01 | 2026-06-08 | |
| Predicting Non-small Cell Lung Cancer (NSCLC) Lymph Node Metastasis: Integrating Circulating Tumor DNA (ctDNA) Mutation/ Methylation Profiling With Positron Emission Tomography-computed Tomography (PET-CT) Scan Blood ctDNA + methylation + PET-CT and Postoperative pathology, MRD+ methylation (or combined with PET-CT) and Invasive mediastinoscopy /EBUS-TBNA, Intraoperative lymph node dissection - Carcinoma, Non-small Cell Lung Cancer | Recruiting | Shanghai Chest Hospital | 200 | 2023-12-15 | 2025-05-18 | |
| SMAD4 Methylation and Expression Levels in Non-melanocytic Skin Cancers; SMAD4 Protein Positivity SMAD4 expression and methylation - Basal Cell Carcinoma | Not applicable | Unknown | Trakya University | 75 | 2020-12-01 | 2021-02-18 |
| Hepatobiliary Tumors Tissue Samples Acquisition Gene expression analysis, Genomic analysis, Protein expression analysis - Hepatocellular Carcinoma, Cholangiocarcinoma | Unknown | Peking Union Medical College Hospital | 450 | 2020-10-11 | 2023-07-07 | |
| Ohio Colorectal Cancer Prevention Initiative LS tumor screening, Genetic testing, Genetic Counseling - Lynch Syndrome, Colorectal Cancer | Not applicable | Completed | Ohio State University Comprehensive Cancer Center | 3470 | 2012-12-26 | 2018-06-28 |
| PTEN and IGFBP-3 Correlation in Ovarian Carcinoma Invasion immunohistochemical, methylation, gene transfection - Ovarian Cancer | Not applicable | Withdrawn | National Taiwan University Hospital | 2006-01-01 | 2012-12-27 |
Biliary Tract Neoplasms (1) · Carcinoma (1) · Carcinoma, Basal Cell (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Non-Small-Cell Lung (1) · Cholangiocarcinoma (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Colorectal Neoplasms, Hereditary Nonpolyposis (1) · Endometrial Neoplasms (1) · Gallbladder Neoplasms (1) · Keratosis, Actinic (1) · Liver Neoplasms (1) · Lymphatic Metastasis (1) · Ovarian Neoplasms (1)
National Taiwan University Hospital (1) · Ohio State University Comprehensive Cancer Center (1) · Peking Union Medical College Hospital (1) · Shanghai Chest Hospital (1) · The University of Hong Kong (1) · Trakya University (1)
China (2) · Hong Kong (1) · Taiwan (1) · Turkey (Türkiye) (1) · United States (1)
Fatma El Usturali Keskin, MD (1) · Haitao Zhao, MD (1) · Heather Hampel, MS, LGC (1) · Metin Budak (1) · Torng Pao-Ling, MD, PhD (1) · Yildiz Gursel, MD (1)
PMID 26291008, PMID 28445469, PMID 28899864, PMID 29968853, PMID 31439586, PMID 37428273, PMID 39444874