8 completed, 4 unknown. 12 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 12 | Completed 8, Unknown 4 |
Follow Methoxyflurane: new trials by email Literature Review of Methoxyflurane trials Research Report on Methoxyflurane
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| 3 mL Inhaled Methoxyflurane for Intrauterine Device (IUD) Insertion Methoxyflurane, Saline - IUD | Phase 4 | Completed | Women's College Hospital | 110 | 2026-04-27 | 2026-10-13 |
| Prehospital Analgesia in Adults Using Inhaled Methoxyflurane Study Methoxyflurane, Standard Care - Pain, Acute | Phase 4 | Unknown | Ottawa Hospital Research Institute | 1800 | 2024-08-01 | 2024-07-19 |
| Prehospital Inhaled Methoxyflurane Non-Clinical Occupational Exposure Study Methoxyflurane - Occupational Exposure | Phase 4 | Unknown | Ottawa Hospital Research Institute | 30 | 2023-09-01 | 2024-07-19 |
| Prehospital Analgesia in Adults Using Inhaled Methoxyflurane : A Feasibility Study Methoxyflurane - Pain, Acute, Trauma | Phase 4 | Completed | Ottawa Hospital Research Institute | 97 | 2021-04-12 | 2023-02-28 |
| Influence of METHoxyflurane on ANtiplatelet Effect of Ticagrelor in Patients With Unstable Angina Pectoris Ticagrelor followed with Methoxyflurane, Ticagrelor followed with Morphine, Ticagrelor alone - Unstable Angina | Phase 4 | Completed | Collegium Medicum w Bydgoszczy | 72 | 2020-06-01 | 2024-03-12 |
| Low Dose Methoxyflurane for Pain Relief During Minor Out-patient Urologic Procedures Methoxyflurane, MEOF - Pain, Acute | Phase 4 | Unknown | Sunnybrook Health Sciences Centre | 10 | 2020-05-31 | 2020-06-02 |
| Penthrox in Rezūm BPH Methoxyflurane - Pain, BPH | Phase 4 | Completed | Dean Elterman | 10 | 2019-09-10 | 2022-01-24 |
| MethOxyflUraNe at moderaTe High AltItudes for PAIN Management Methoxyflurane, Placebo - Pain | Phase 4 | Unknown | University of Cape Town | 24 | 2019-05-01 | 2019-02-21 |
| Determination of Analgesic Equipotent Doses of Inhaled Metoxyflurane vs. Intravenous Fentanyl Methoxyflurane (M), Fentanyl (F1), Fentanyl (F2) - Acute Pain, Trauma | Phase 4 | Completed | Oslo University Hospital | 12 | 2019-04-23 | 2019-11-19 |
| PENTHROX™ in the Canadian Emergency Department (ED) Methoxyflurane 3mL - Pain, Acute | Phase 4 | Completed | Purdue Pharma, Canada | 99 | 2019-04-08 | 2021-09-16 |
| Efficacy and Safety of Penthrox® Combined With a Standard Analgesia (SoC) in Adult Patients Admitted to the Emergency Department With Moderate to Severe Pain Associated With Trauma Methoxyflurane, Normal Saline - Pain, Acute | Phase 4 | Completed | Mundipharma SAS | 360 | 2018-05-14 | 2019-01-10 |
| Safety and Efficacy of Methoxyflurane for Treatment of Incident Pain Methoxyflurane, Normal Saline - Pain Measurement | Phase 4 | Completed | Medical Developments International Limited | 110 | 2007-09-01 | 2010-01-28 |
Acute Pain (6) · Pain (3) · Wounds and Injuries (2) · Agnosia (1) · Angina, Unstable (1) · Hypovolemia (1)
Ottawa Hospital Research Institute (3) · Collegium Medicum w Bydgoszczy (1) · Dean Elterman (1) · Medical Developments International Limited (1) · Mundipharma SAS (1) · Oslo University Hospital (1) · Purdue Pharma, Canada (1) · Sunnybrook Health Sciences Centre (1) · University of Cape Town (1) · Women's College Hospital (1)
Canada (5) · Australia (1) · France (1) · Norway (1) · Poland (1) · South Africa (1)
A Ricard-Hibon, Dr (1) · Harald Lenz, Phd (1) · Jacek Kubica, Professor (1) · Karim Ladha, MD (1) · Lauren Scott, NP (1) · Michael A Austin, MD (1) · Odette Spruyt, MD (1) · Ross Hofmeyr (1) · Sender Herschorn, MD, FRSC (1) · Sonja Dhani, PhD (1)
PMID 15576519, PMID 17006084, PMID 19254307, PMID 23059961, PMID 24644183, PMID 33676727, PMID 42817920, PMID 496064, PMID 5007074, PMID 6003600
2017 (1), 2018 (1)