4 recruiting, 1 completed. 4 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Recruiting 4 |
| Phase 2 | 1 | Recruiting 1 |
Follow Mesothelin: new trials by email Literature Review of Mesothelin trials Research Report on Mesothelin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mesothelin and Claudin 18.2 Dual-Target CAR-T Therapy in Advanced Pancreatic Cancer Mesothelin and Claudin 18.2 CAR-T cells - Pancreatic Cancer, Pancreatic Carcinoma | Phase 1 / Phase 2 | Recruiting | Essen Biotech | 60 | 2025-04-29 | 2025-07-15 |
| CLDN6/GPC3/Mesothelin/AXL-CAR-NK Cell Therapy for Advanced Solid Tumors Claudin6, GPC3, Mesothelin, or AXL targeting CAR-NK cells - Stage IV Ovarian Cancer, Testis Cancer, Refractory | Phase 1 | Recruiting | Second Affiliated Hospital of Guangzhou Medical University | 200 | 2022-06-01 | 2024-06-25 |
| Engineered TILs/CAR-TILs to Treat Advanced Solid Tumors TILs and CAR-TILs targeting HER2, Mesothelin, PSCA, MUC1, Lewis-Y, GPC3, AXL, EGFR, Claudin18.2/6, ROR1, GD1, or B7-H3 - Liver Cancer, Lung Cancer | Phase 1 | Recruiting | Second Affiliated Hospital of Guangzhou Medical University | 40 | 2021-01-01 | 2024-06-25 |
| GPC3/Mesothelin/Claudin18.2/GUCY2C/B7-H3/PSCA/PSMA/MUC1/TGFβ/HER2/Lewis-Y/AXL/EGFR-CAR-T Cells Against Cancers CAR-T cells targeting GPC3, Mesothelin, Claudin18.2, GUCY2C, B7-H3, PSCA, PSMA, MUC1, TGFβ, HER2, Lewis-Y, AXL, or EGFR - Lung Cancer, Cancer | Phase 1 | Recruiting | Second Affiliated Hospital of Guangzhou Medical University | 30 | 2017-07-01 | 2024-06-25 |
| Serum Biomarkers in Diagnosis of Mesothelioma Mesothelin, hyaluronan, osteopontin, syndecan-1 - Mesothelioma | Completed | Eskisehir Osmangazi University | 230 | 2004-01-01 | 2014-01-07 |
Lung Neoplasms (2) · Brain Neoplasms (1) · Breast Neoplasms (1) · Colonic Neoplasms (1) · Liver Neoplasms (1) · Mesothelioma (1) · Neoplasms (1) · Ovarian Neoplasms (1) · Pancreatic Neoplasms (1) · Pleural Diseases (1) · Testicular Neoplasms (1)
Second Affiliated Hospital of Guangzhou Medical University (3) · Eskisehir Osmangazi University (1) · Essen Biotech (1)
China (4) · Turkey (Türkiye) (1)
Muzaffer Metintas, Prof.Dr. (1) · Zhenfeng Zhang, MD, PHD (1) · Zhenfeng Zhang, MD, PhD (1) · Zhenfeng Zhang, MD,PhD (1)