22 completed. 22 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 22 | Completed 22 |
| Phase 2 | 1 | Completed 1 |
Follow merphos: new trials by email Literature Review of merphos trials Research Report on merphos
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tac, Mini-MTX, MMF Versus Tac, MTX for GVHD Prevention tacrolimus, methotrexate, Mycophenolate mofetil - Chronic Myelogenous Leukemia, Acute Lymphoblastic Leukemia | Phase 3 | Completed | Case Comprehensive Cancer Center | 101 | 2014-07-07 | 2023-09-11 |
| Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia Dactinomycin, Leucovorin Calcium, Methotrexate - Choriocarcinoma, FIGO Stage I Gestational Trophoblastic Tumor | Phase 3 | Completed | GOG Foundation | 57 | 2012-06-18 | 2022-08-12 |
| Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations Clofarabine, Cyclophosphamide, Cytarabine - B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, BCR-ABL1-Like | Phase 3 | Completed | National Cancer Institute (NCI) | 5949 | 2012-02-29 | 2026-06-02 |
| Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma Cyclophosphamide, Cytarabine, Dexamethasone - Acute Lymphoblastic Leukemia, Adult B Lymphoblastic Lymphoma | Phase 3 | Completed | Children's Oncology Group | 9350 | 2010-08-11 | 2026-05-28 |
| Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Promyelocytic Leukemia Arsenic Trioxide, Cytarabine, Diagnostic Laboratory Biomarker Analysis - Childhood Acute Promyelocytic Leukemia With PML-RARA, Myeloid Neoplasm | Phase 3 | Completed | Children's Oncology Group | 106 | 2009-03-09 | 2022-10-25 |
| Combination Chemotherapy, Radiation Therapy, and an Autologous Peripheral Blood Stem Cell Transplant in Treating Young Patients With Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System 3-Dimensional Conformal Radiation Therapy, Autologous Hematopoietic Stem Cell Transplantation, Carboplatin - Childhood Atypical Teratoid/Rhabdoid Tumor | Phase 3 | Completed | Children's Oncology Group | 70 | 2009-02-10 | 2024-04-23 |
| Calaspargase Pegol or Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia Calaspargase Pegol-mknl, Cyclophosphamide, Cytarabine - Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia | Phase 3 | Completed | Children's Oncology Group | 166 | 2008-07-21 | 2021-04-27 |
| Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Asparaginase, Cyclophosphamide, Cytarabine - Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 | Phase 2 / Phase 3 | Completed | National Cancer Institute (NCI) | 63 | 2008-07-14 | 2020-04-13 |
| Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Asparaginase, Biospecimen Collection, Bone Marrow Biopsy - Acute Lymphoblastic Leukemia, Acute Undifferentiated Leukemia | Phase 3 | Completed | Children's Oncology Group | 218 | 2008-01-15 | 2024-07-15 |
| Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma Autologous Hematopoietic Stem Cell Transplantation, Carboplatin, Cisplatin - Anaplastic Medulloblastoma, Medulloblastoma | Phase 3 | Completed | Children's Oncology Group | 91 | 2007-10-22 | 2026-01-23 |
| Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia vincristine sulfate, prednisone, doxorubicin hydrochloride - B-cell Childhood Acute Lymphoblastic Leukemia, L1 Childhood Acute Lymphoblastic Leukemia | Phase 3 | Completed | Children's Oncology Group | 275 | 2007-03-01 | 2024-03-26 |
| Tacrolimus and Methotrexate With or Without Sirolimus in Preventing Graft-Versus-Host Disease in Young Patients Undergoing Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia in Complete Remission thiotepa, cyclophosphamide, tacrolimus - B-cell Childhood Acute Lymphoblastic Leukemia, Childhood Acute Lymphoblastic Leukemia in Remission | Phase 3 | Completed | Children's Oncology Group | 146 | 2007-03-01 | 2019-08-07 |
| Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma Asparaginase, Cyclophosphamide, Cytarabine - T Acute Lymphoblastic Leukemia, T Lymphoblastic Lymphoma | Phase 3 | Completed | National Cancer Institute (NCI) | 1895 | 2007-01-30 | 2026-06-23 |
| Low-Dose or High-Dose Conditioning Followed by Peripheral Blood Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Myelogenous Leukemia total-body irradiation, allogeneic hematopoietic stem cell transplantation, cyclophosphamide - Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Acute Myeloid Leukemia/Transient Myeloproliferative Disorder | Phase 3 | Completed | Fred Hutchinson Cancer Center | 25 | 2006-01-01 | 2014-10-31 |
| Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With Osteosarcoma Cisplatin, Doxorubicin Hydrochloride, Etoposide - Localized Osteosarcoma, Metastatic Osteosarcoma | Phase 3 | Completed | Children's Oncology Group | 1334 | 2005-11-14 | 2023-06-07 |
| Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia 3-Dimensional Conformal Radiation Therapy, Cyclophosphamide, Cytarabine - Acute Lymphoblastic Leukemia, Childhood B Acute Lymphoblastic Leukemia | Phase 3 | Completed | Children's Oncology Group | 5377 | 2005-04-11 | 2021-06-14 |
| Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia Cyclophosphamide, Cytarabine, Daunorubicin Hydrochloride - Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia | Phase 3 | Completed | Children's Oncology Group | 3154 | 2003-12-29 | 2021-04-27 |
| Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Children With Acute Lymphoblastic Leukemia filgrastim, asparaginase, cyclophosphamide - Childhood Acute Lymphoblastic Leukemia in Remission, Recurrent Childhood Acute Lymphoblastic Leukemia | Phase 3 | Completed | National Cancer Institute (NCI) | 220 | 2002-10-01 | 2014-02-27 |
| Comparison of Immediate and Delayed Adjuvant Chemotherapy in Treating Patients Who Have Undergone a Radical Cystectomy for Stage III or Stage IV Transitional Cell Carcinoma of the Bladder Urothelium doxorubicin hydrochloride, gemcitabine hydrochloride, vinblastine sulfate - Stage III Bladder Cancer, Stage IV Bladder Cancer | Phase 3 | Completed | European Organisation for Research and Treatment of Cancer - EORTC | 285 | 2001-10-01 | 2016-08-02 |
| Tretinoin, Cytarabine, and Daunorubicin Hydrochloride With or Without Arsenic Trioxide Followed by Tretinoin With or Without Mercaptopurine and Methotrexate in Treating Patients With Acute Promyelocytic Leukemia tretinoin, daunorubicin hydrochloride, cytarabine - Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Promyelocytic Leukemia (M3) | Phase 3 | Completed | National Cancer Institute (NCI) | 420 | 1999-06-01 | 2013-06-05 |
Showing 20 of 22. Sign in to see all of them.
Precursor Cell Lymphoblastic Leukemia-Lymphoma (10) · Burkitt Lymphoma (3) · Hydatidiform Mole (2) · Leukemia, Biphenotypic, Acute (2) · Leukemia, Myeloid, Acute (2) · Myeloproliferative Disorders (2) · Anemia, Refractory (1) · Anemia, Refractory, with Excess of Blasts (1) · Choriocarcinoma (1) · Chromosome 5q Deletion Syndrome (1) · Congenital Abnormalities (1) · Down Syndrome (1) · Graft vs Host Disease (1) · Hodgkin Disease (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1)
Children's Oncology Group (11) · National Cancer Institute (NCI) (6) · Case Comprehensive Cancer Center (1) · European Organisation for Research and Treatment of Cancer - EORTC (1) · Fred Hutchinson Cancer Center (1) · GOG Foundation (1) · Gynecologic Oncology Group (1)
United States (21) · Canada (14) · Australia (12) · New Zealand (8) · Switzerland (7) · Puerto Rico (6) · Ireland (2) · Germany (1) · Japan (1) · South Korea (1) · United Kingdom (1)
Anne L Angiolillo (2) · Alyssa T Reddy (1) · Bart Scott (1) · Bayard Powell (1) · Betty Hamilton, MD (1) · Beverly Lange (1) · Claire M Mazewski (1) · Cora Sternberg, Dr. (1) · Eric C Larsen (1) · Glen Lew, MD (1) · Joanne M Hilden (1) · John J Gregory (1) · Julian C Schink (1) · Kelly W Maloney (1) · Kirk Schultz (1)
PMID 37890117, PMID 39121442, PMID 26590194, PMID 29284596, PMID 33242441, PMID 38446568, PMID 40315406, PMID 42085640, PMID 19304957, PMID 20056794, PMID 20413658, PMID 20705755, PMID 23678006, PMID 24497539, PMID 24970932, PMID 25421877, PMID 25498218, PMID 25862561, PMID 26124497, PMID 26265699, PMID 27569442, PMID 29812996, PMID 30138085, PMID 30626253, PMID 31401903, PMID 32001530, PMID 32414848, PMID 32460997, PMID 32496902, PMID 32552472, PMID 32730180, PMID 32813610, PMID 33411585, PMID 33496745, PMID 34302711, PMID 35246418, PMID 36603187, PMID 36815378, PMID 37352262, PMID 37556734, PMID 38295280, PMID 39515374, PMID 40533067, PMID 41592282, PMID 42085603
U10CA098543 (16), U10CA180886 (7), U10CA027469 (2), 2004 (1), 2005 (1), K23HL084054 (1), N02CM62212 (1), P01CA018029 (1), P01CA078902 (1), P01HL036444 (1), U10CA031946 (1), U10CA180868 (1)