27 completed, 3 unknown, 2 recruiting, 2 terminated. 14 Not applicable, 10 Phase 4, 6 Phase 2, 4 Phase 3, 2 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Magnesium Supplementation on Sleep Quality and Cognitive Function in Saudi Adults Magnesium 400Mg - Healthy, Health Adult Subjects | Not applicable | Completed | Umm Al-Qura University | 41 | 2024-10-01 | 2026-08-18 |
| Microbiota Transfer Therapy for Children and Adults With Both Pitt Hopkins Syndrome and Gastrointestinal Disorders MTP-101P, Vancomycin, Magnesium Citrate - Pitt Hopkins Syndrome | Phase 2 | Unknown | Gut-Brain-Axis Therapeutics Inc. | 20 | 2024-02-27 | 2024-03-20 |
| Clinical Evaluation of the Magnesium Absorption Kinetics in Human Plasma Upon Oral Intake of Magnesium-based Products Dietary supplementation with Microencapsulated Magnesium, Dietary supplementation with Magnesium Oxide, Dietary supplementation with Magnesium Citrate - Healthy Volunteers | Not applicable | Completed | Bionos Biotech S.L. | 40 | 2024-01-28 | 2024-08-20 |
| PEG-Asc Vs. SPMC for Bowel Preparation in Capsule-based Procedures Polyethylene Glycol plus Ascorbic Acid (PEG-Asc), Sodium Picosulfate with Magnesium Citrate (SPMC) - Bowel Preparation Solution | Not applicable | Completed | Unidade Local de Saúde do Alto Ave, EPE | 220 | 2024-01-01 | 2025-10-03 |
| Magnesium Citrate in Chronic Masticatory Myofascial Pain Magnesium citrate, Behavioral counseling - Chronic Masticatory Myofascial Pain | Not applicable | Completed | Muhammet Yasin Pektaş | 50 | 2023-07-01 | 2026-10-06 |
| The Heart Failure Diuresis Efficacy Comparison (DEA-HF) Study IV Furosemide, IV Furosemide and PO Metolazone, IV Furosemide and IV Acetazolamide - Chronic Heart Failure, Diuretics Drug Reactions | Phase 4 | Completed | Rambam Health Care Campus | 42 | 2023-04-19 | 2024-05-21 |
| The Exploration of the Regulatory Effect of Magnesium on Intestinal Flora in Healthy Adults Magnesium Citrate - Healthy State | Not applicable | Completed | The Seventh Affiliated Hospital, Southern Medical University | 41 | 2022-10-15 | 2024-10-09 |
| "CHANGE COVID-19 Severity" Magnesium Citrate plus probiotic - COVID-19 Infection | Phase 1 / Phase 2 | Terminated | Vanderbilt University Medical Center | 23 | 2021-11-04 | 2023-11-13 |
| Better Evidence and Translation for Calciphylaxis Vitamin K1, Magnesium citrate, Sodium Thiosulfate - Calciphylaxis | Phase 3 | Recruiting | University of Sydney | 350 | 2021-08-26 | 2025-08-13 |
| RELISTOR's Effects on Opioid-Induced Constipation Relistor Injectable Product, Docusate Calcium, Bisacodyl - OIC | Withdrawn | Methodist Health System | 2021-07-01 | 2026-03-23 | ||
| Comparison of 1 Liter PEG With Ascorbate and Sodium Picosulfate / Magnesium Citrate for High Quality Colon Cleansing Polyethylene glycol + ascorbate, Sodium picosulfate + magnesium citrate - Colonic Diseases | Phase 4 | Completed | Parc de Salut Mar | 1180 | 2020-11-06 | 2026-05-14 |
| The Effect of Magnesium Citrate Supplementation in Restless Legs Syndrome (RLS) Magnesium Citrate - Restless Legs Syndrome | Not applicable | Unknown | OSF Healthcare System | 15 | 2020-07-10 | 2023-02-17 |
| MTT for Children With Both Pitt Hopkins Syndrome and Gastrointestinal Disorders vancomycin, magnesium citrate, microbiota, placebo vancomycin, real magnesium citrate, placebo microbiota - Pitt Hopkins Syndrome | Phase 2 | Completed | Arizona State University | 6 | 2019-09-30 | 2024-08-26 |
| Magnesium Supplementation in Diabetic Nephropathy Magnesium citrate, Antidiabetic - Diabetic Nephropathies | Phase 2 | Completed | Ain Shams University | 60 | 2019-06-01 | 2021-01-12 |
| Comparison of Different Low Volume Solutions Prior to Colonoscopy Natrium picosulfate / Magnesium citrate, Polyethylene glycol / Ascorbic acid, Natrium/ Kalium/ Magnesium sulfate - Colonoscopy | Phase 4 | Completed | Tomas Bata Hospital, Czech Republic | 612 | 2018-10-25 | 2019-03-08 |
| Effects of Magnesium Supplementation on Hemodynamic Parameters and Cognitive Function Magnesium Citrate, Food grade citrate acid, Splenda(Sucralose) - Cognitive Function | Not applicable | Completed | Academia Sinica, Taiwan | 50 | 2018-10-23 | 2022-01-26 |
| Bioavailability of Single-dose Magnesium Salts Picometer-ionic form of magnesium chloride, Magnesium citrate or magnesium oxide, Placebo - Bioavailability | Not applicable | Completed | Think Healthy Group, Inc. | 17 | 2018-08-01 | 2024-04-23 |
| Magnesium and Vascular Stiffness Magnesium Citrate, Magnesium Sulfate, Magnesium Oxide - Vascular Stiffness, Blood Pressure | Not applicable | Unknown | University Medical Center Groningen | 162 | 2018-03-27 | 2018-08-15 |
| Testing How Well Magnesium Citrate Capsules Work as Preparation for a Colonoscopy Magnesium Citrate Capsules, Polyethylene Glycol 3350, Dulcolax Tablets - Colonoscopy | Not applicable | Completed | LifeBridge Health | 62 | 2017-09-26 | 2021-03-09 |
| Magnesium Deficiency In Patients Hospitalized in Internal Medicine Wards Magnesium Citrate 100 MG - Hypomagnesemia | Phase 4 | Recruiting | Frieda Wolf | 330 | 2017-05-10 | 2025-03-18 |
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Obesity (2) · Pitt-Hopkins syndrome (2) · COVID-19 (1) · Calciphylaxis (1) · Cardiovascular Diseases (1) · Colonic Diseases (1) · Colorectal Neoplasms (1) · Constipation (1) · Diabetes Mellitus, Type 2 (1) · Diabetes, Gestational (1) · Diabetic Nephropathies (1) · Essential Hypertension (1) · Gestational Weight Gain (1) · Heart Failure (1) · Hypertension (1)
Tomas Bata Hospital, Czech Republic (2) · Academia Sinica, Taiwan (1) · Ain Shams University (1) · Arizona State University (1) · Bionos Biotech S.L. (1) · Clinical Hospital Colentina (1) · Frieda Wolf (1) · Gut-Brain-Axis Therapeutics Inc. (1) · Halina M Zyczynski, MD (1) · Korea University Anam Hospital (1) · LifeBridge Health (1) · Luigi Sacco University Hospital (1) · Maastricht University Medical Center (1) · Methodist Health System (1) · Muhammet Yasin Pektaş (1)
United States (11) · Israel (3) · Canada (2) · Czechia (2) · Netherlands (2) · South Korea (2) · Spain (2) · Australia (1) · Brazil (1) · China (1) · Egypt (1) · Germany (1) · Italy (1) · New Zealand (1) · Portugal (1)
Aharon Abbo, MD (1) · Alaa Rostom, MD (1) · Bun Kim, Dr (1) · David Pajuelo Gamez, PhD (1) · Erik Garpestad, MD (1) · Ethan Dubin, MD (1) · Eun Sun Kim (1) · Frieda Wolf (1) · Gianpiero Manes, MD (1) · Halina M Zyczynski, MD (1) · Joao G Alves, PhD (1) · Joel M Neutel, MD (1) · Kelly L Kantartzis, MD (1)
PMID 22433473, PMID 25005784, PMID 25019969, PMID 27053384, PMID 30921345, PMID 31138315, PMID 32272914, PMID 32316938, PMID 32353962, PMID 33030273, PMID 35253448, PMID 38056458, PMID 38107482, PMID 38738598, PMID 39186385, PMID 41810820