8 completed, 6 recruiting, 3 not yet recruiting, 3 unknown. 6 Not applicable, 5 Phase 3, 5 Phase 4, 3 Phase 2, 2 Early Phase 1.
Follow Low-Dose Aspirin: new trials by email Literature Review of Low-Dose Aspirin trials Research Report on Low-Dose Aspirin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Low Dose Aspirin to Lower Inflammation and Prevent Endometrial Cancer in Postmenopausal Women With Non-atrophic Endometrial Changes and Pain Biospecimen Collection, Low-Dose Aspirin, Patient Observation - Endometrial Carcinoma | Phase 4 | Not yet recruiting | Mayo Clinic | 20 | 2027-02-12 | 2026-08-05 |
| Low Dose Aspirin vs Placebo in Prevention of Recurrent Spontaneous Preterm Labour Low-dose Aspirin, Placebo - Preterm Labor, Premature Birth | Not applicable | Not yet recruiting | University of Health Sciences Lahore | 162 | 2026-08-20 | 2026-08-12 |
| Can Aspirin Reduce the Risk of HCC in Cirrhosis: The AspiRe HCC Trial Low-dose aspirin, Placebo Comparator - Liver Cirrhosis | Phase 3 | Not yet recruiting | Curtin University | 890 | 2026-06-01 | 2026-04-14 |
| Comparison of Pregnancy Outcomes in Primigravida Receiving Low-Dose Aspirin for the Prevention of Preeclampsia. Low-dose aspirin, No-Aspirin - Preeclampsia | Not applicable | Completed | Muhammad Aamir Latif | 160 | 2025-08-01 | 2026-10-01 |
| One-Month DAPT in CABG Patients Ticagrelor 90 MG, Low-dose aspirin - Chronic Coronary Disease | Phase 3 | Recruiting | Weill Medical College of Cornell University | 700 | 2024-08-15 | 2025-12-22 |
| Treatment With Aspirin After Preeclampsia: TAP Trial Low-dose aspirin, Placebo - Hypertensive Disorder of Pregnancy, Pre-Eclampsia | Phase 4 | Recruiting | Malamo Countouris | 60 | 2024-05-29 | 2026-09-22 |
| A Study to Evaluate P1101 in Japanese PV Patients P1101, Low-dose aspirin, Phlebotomy - Polycythemia Vera (PV) | Phase 3 | Completed | PharmaEssentia Japan K.K. | 21 | 2023-10-17 | 2024-11-08 |
| Aspirin Dose Comparison in Elderly PCI Patients: 30mg vs. 75mg in Acute Coronary Syndrome Low-dose aspirin - Myocardial Infarction, Acute Coronary Syndrome | Phase 2 | Unknown | Medical University of Warsaw | 40 | 2023-07-03 | 2024-02-12 |
| Non-surgical Periodontitis Treatment With Aspirin and Omega-3 Scaling and Root Planing (SRP), Omega-3 Fatty Acids, Low-dose aspirin - Periodontitis, Periodontitis (Stage 3) | Not applicable | Active not recruiting | Hanoi Medical University | 120 | 2023-04-01 | 2026-04-15 |
| Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer Biospecimen Collection, Low-Dose Aspirin, Questionnaire Administration - Breast Carcinoma | Phase 2 | Recruiting | Mayo Clinic | 60 | 2023-03-09 | 2026-10-01 |
| LDA and LMWH vs LDA Alone in High-risk Patients for Preeclampsia Prevention Aspirin, Tinzaparin - Preeclampsia Severe, Toxemia Of Pregnancy | Phase 4 | Recruiting | Alexandra Hospital, Athens, Greece | 100 | 2023-01-18 | 2026-01-23 |
| AVAJAK: Apixaban/Rivaroxaban Versus Aspirin for Primary Prevention of Thrombo-embolic Complications in JAK2V617F-positive Myeloproliferative Neoplasms Direct Oral Anticoagulants, Low-dose aspirin - Polycythemia Vera, Essential Thrombocythemia | Phase 3 | Recruiting | University Hospital, Brest | 1308 | 2022-07-13 | 2026-03-20 |
| The Investigation of the Prediction Model and Prevention Strategy of Serious Pregnancy Complications in Hypertensive Disorders of Pregnancy Based on the Chinese Population Low-dose aspirin - Hypertensive Disorder of Pregnancy, Pregnancy Complications | Unknown | Women's Hospital School Of Medicine Zhejiang University | 4500 | 2021-11-30 | 2021-12-02 | |
| Adherence to Universal Aspirin Compared to Screening Indicated Aspirin for Prevention of Preeclampsia Low-dose aspirin - Medication Adherence, Preeclampsia | Phase 4 | Withdrawn | Women and Infants Hospital of Rhode Island | 2021-03-03 | 2025-04-04 | |
| Hydroxychloroquine in Prevention of Preeclampsia Hydroxychloroquine, Folic acid, Low-dose aspirin - Preeclampsia | Not applicable | Completed | Assiut University | 50 | 2021-03-01 | 2023-12-08 |
| Identification of Critical Thermal Environments for Aged Adults Low dose ASA, Control - Aging | Early Phase 1 | Recruiting | Penn State University | 190 | 2020-12-30 | 2026-01-27 |
| Low-dose Aspirin Therapy in Patients With Ischemic Stroke and Microbleeds low-dose aspirin, conventional-does aspirin - Ischemic Stroke | Phase 4 | Unknown | Xijing Hospital | 400 | 2020-10-01 | 2022-02-09 |
| Postpartum Low-Dose Aspirin After Preeclampsia for Optimization of Cardiovascular Risk (PAPVASC) Low-dose aspirin, Placebo oral tablet - Preeclampsia Severe, Cardiovascular Diseases | Early Phase 1 | Terminated | Dr. Graeme Smith | 14 | 2020-09-14 | 2024-04-05 |
| Low Dose Aspirin for Preventing Intrauterine Growth Restriction and Preeclampsia in Sickle Cell Pregnancy (PIPSICKLE) Low-dose aspirin, Placebo - Intrauterine Growth Restriction, Preeclampsia | Phase 3 | Completed | University of Lagos, Nigeria | 476 | 2020-07-01 | 2025-01-09 |
| Hydroxychloroquine and Unexplained Recurrent Miscarriage Hydroxychloroquine, Folic Acid, Low-dose aspirin - Unexplained Recurrent Miscarriage | Not applicable | Completed | Assiut University | 156 | 2020-01-01 | 2023-12-07 |
Showing 20 of 23. Sign in to see all of them.
Pre-Eclampsia (7) · Pregnancy Complications (4) · Cardiovascular Diseases (3) · Polycythemia Vera (3) · Toxemia (3) · Hypertension, Pregnancy-Induced (2) · Myeloproliferative Disorders (2) · Acute Coronary Syndrome (1) · Anemia, Sickle Cell (1) · Breast Neoplasms (1) · Carcinoma (1) · Colorectal Neoplasms (1) · Eclampsia (1) · Endometrial Neoplasms (1) · Fetal Growth Retardation (1)
Assiut University (2) · Mayo Clinic (2) · PharmaEssentia Japan K.K. (2) · Alexandra Hospital, Athens, Greece (1) · Bayer (1) · Curtin University (1) · Dr. Graeme Smith (1) · Hanoi Medical University (1) · Malamo Countouris (1) · Medical University of Warsaw (1) · Muhammad Aamir Latif (1) · Penn State University (1) · University Hospital, Brest (1) · University of Health Sciences Lahore (1) · University of Lagos, Nigeria (1)
United States (6) · China (3) · Canada (2) · Egypt (2) · Japan (2) · Austria (1) · Finland (1) · France (1) · Germany (1) · Greece (1) · Italy (1) · Nigeria (1) · Pakistan (1) · Poland (1) · Sweden (1)
Alisse K Hauspurg, MD (1) · Baohua Li, Phd (1) · Bosede B Afolabi, DM (Nott) (1) · Christopher C. DeStephano, MD, MPH (1) · Georgios Daskalakis, PhD (1) · Graeme N Smith, MD, PhD (1) · Hannu Martikainen, MD (1) · Helena Tinkanen, MD (1) · John K Olynyk, BMedSc MBBS FRACP MD FAASLD (1) · Juha Rasanen, MD (1) · Juha S Tapanainen, Prof (1) · Kathryn J. Ruddy, MD (1) · Marc Ruel, MD, MPH (1) · Mario Gaudino, MD, PhD, MSCE (1) · Mariusz Tomaniak, PhD (1)
PMID 19153091, PMID 20943705, PMID 24711050, PMID 26551178, PMID 29217662, PMID 29562586, PMID 29748422, PMID 30056389, PMID 30870274, PMID 32114852, PMID 38436365, PMID 40313042, PMID 41713441
2023 (1), K23HL168356 (1), R01CA262393 (1)