15 completed, 1 terminated, 1 unknown. 6 Phase 4, 5 Phase 3, 4 Phase 2, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 6 | Completed 4, Terminated 1, Unknown 1 |
| Phase 3 | 5 | Completed 5 |
| Phase 2 | 4 | Completed 4 |
| Not applicable | 2 | Completed 2 |
Follow this drug Literature Review of Levalbuterol trials Research Report on Levalbuterol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Levalbuterol Compared to Albuterol Regarding Cardiac Side Effects and Potassium Lowering Effects. Levalbuterol, Albuterol - Hyperkalemia | Phase 4 | Unknown | University of Aleppo | 30 | 2021-11-04 | 2021-12-30 |
| Evaluation of Dupilumab in Patients With Severe Steroid Dependent Asthma Dupilumab, Placebo, Oral corticosteroid therapy (prednisone/prednisolone) - Asthma | Phase 3 | Completed | Sanofi | 210 | 2015-10-15 | 2019-10-01 |
| Change in Oxygen Consumption Following Inhalation Beta Agonists in Healthy Adults Albuterol, Levalbuterol - Oxygen Consumption | Not applicable | Completed | Children's Hospital Los Angeles | 24 | 2015-06-01 | 2020-10-28 |
| Evaluation of Dupilumab in Patients With Persistent Asthma (Liberty Asthma Quest) Dupilumab, Placebo, Inhaled corticosteroid (ICS) therapy - Asthma | Phase 3 | Completed | Sanofi | 1902 | 2015-04-27 | 2018-10-23 |
| An Evaluation of Dupilumab in Patients With Moderate to Severe Uncontrolled Asthma Dupilumab, placebo, ICS/LABA therapy - Asthma | Phase 2 | Completed | Sanofi | 776 | 2013-06-01 | 2017-06-26 |
| COPD Assessment and Management Bundle Versus Usual Care Spirometry test, Levalbuterol - Chronic Obstructive Pulmonary Disease | Not applicable | Completed | University of Illinois at Chicago | 56 | 2013-03-01 | 2019-12-24 |
| Efficacy, Safety, and Tolerability of Dupilumab in Patients With Persistent Moderate to Severe Eosinophilic Asthma Dupilumab, Placebo (for Dupilumab), Fluticasone/Salmeterol combination therapy - Asthma | Phase 2 | Completed | Sanofi | 104 | 2011-03-01 | 2017-06-08 |
| A Pilot Study to Determine the Most Effective Dose of Arformoterol for Treating Acute Asthmatic Patients arformoterol (RR formoterol), placebo, levalbuterol - Acute Asthma | Phase 4 | Terminated | Henry Ford Health System | 2 | 2009-01-01 | 2023-05-24 |
| A Safety, Efficacy and Tolerability Study in Pediatric Subjects With Asthma Levalbuterol, Levalbuterol UDV TID, Placebo - Asthma | Phase 3 | Completed | Sumitomo Pharma America, Inc. | 197 | 2008-12-01 | 2014-07-28 |
| Effect of Nebulized Bronchodilators on Heart Rate Levalbuterol, Albuterol - COPD, Sepsis | Phase 4 | Completed | Fahim Khorfan, MD | 89 | 2008-12-01 | 2015-10-23 |
| A Safety and Tolerability Study of Arformoterol Tartrate Inhalation Solution in Pediatric Subjects arformoterol, levalbuterol - Asthma | Phase 2 | Completed | Sumitomo Pharma America, Inc. | 53 | 2008-01-01 | 2012-02-22 |
| Aerosolized Beta-Agonist Isomers in Asthma levalbuterol, saline, levalbuterol MDI - Asthma | Phase 4 | Completed | Duke University | 10 | 2007-07-01 | 2014-08-13 |
| Albuterol Versus Xopenex in Treatment of Acute Asthma in the Emergency Department (ED) xopenex - Asthma | Phase 4 | Completed | Phoenix Children's Hospital | 101 | 2005-09-01 | 2026-02-10 |
| Continuous Levalbuterol for Treatment of Status Asthmaticus in Children Racemic albuterol (R+S albuterol), Levalbuterol (R albuterol) - Asthma | Phase 4 | Completed | Children's Hospital of Philadelphia | 81 | 2004-04-01 | 2013-03-14 |
| Study of Levalbuterol, Racemic Albuterol and Placebo in Subjects Twelve Years of Age and Older With Asthma levalbuterol - Asthma | Phase 3 | Completed | Sumitomo Pharma America, Inc. | 386 | 2002-12-01 | 2012-02-22 |
| A Study of Daily Dosing With Levalbuterol, Racemic Albuterol, and Placebo in Pediatric Subjects With Asthma levalbuterol 90 mcg, levalbuterol 180 mcg, racemic albuterol 180 mcg - Asthma | Phase 2 | Completed | Sumitomo Pharma America, Inc. | 146 | 2001-10-01 | 2012-08-03 |
| Efficacy and Safety of Levalbuterol Versus Racemic Albuterol in Asthma Levalbuterol 1.25 mg, Racemic Albuterol Sulfate - Asthma | Phase 3 | Completed | Sumitomo Pharma America, Inc. | 627 | 2000-11-01 | 2012-02-22 |
Asthma (13) · Pulmonary Disease, Chronic Obstructive (2) · Emergencies (1) · Hyperkalemia (1) · Lung Diseases (1) · Respiratory Tract Diseases (1) · Sepsis (1) · Shock (1) · Tachycardia (1)
Sumitomo Pharma America, Inc. (5) · Sanofi (4) · Children's Hospital Los Angeles (1) · Children's Hospital of Philadelphia (1) · Duke University (1) · Fahim Khorfan, MD (1) · Henry Ford Health System (1) · Phoenix Children's Hospital (1) · University of Aleppo (1) · University of Illinois at Chicago (1)
United States (13) · Argentina (3) · Chile (3) · Italy (3) · Mexico (3) · Poland (3) · Russia (3) · Spain (3) · Ukraine (3) · Australia (2) · Brazil (2) · Canada (2) · Colombia (2) · France (2) · Hungary (2)
Baraa Shebli, M.D. (1) · Fahim Khorfan, MD (1) · John Hanrahan, M.D. (1) · Joseph J Zorc, MD (1) · Kimberly R Barber, PhD (1) · Mahmoud Malhis, MRCP (1) · Min Joo, MD, MPH (1) · Neil MacIntyre, MD (1) · Patrick A Ross, MD (1) · Richard M Nowak, MD (1) · Robert Bulloch, MD (1)
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2014 (1), 2015 (1), K23HL094461 (1)