5 unknown, 3 completed, 1 not yet recruiting, 1 recruiting. 5 Not applicable, 3 Phase 3, 2 Phase 2, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Unknown 4, Withdrawn 1 |
| Phase 3 | 3 | Completed 1, Recruiting 1, Unknown 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow Intravenous normal saline: new trials by email Literature Review of Intravenous normal saline trials Research Report on Intravenous normal saline
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ketamine for Postherpetic Neuralgia With Depression Intravenous Ketamine Infusions, Intravenous normal saline, Oral Duloxetine 60mg - Depression Disorders, Herpetic Neuralgia | Phase 4 | Not yet recruiting | Huazhong University of Science and Technology | 50 | 2025-06-15 | 2025-06-03 |
| Contribution of Ondansetron to Preventing Post-Dural Puncture Headaches Following Spinal Anesthesia Intravenous ondansetron, Intravenous normal saline - Post-Dural Puncture Headache | Not applicable | Unknown | Mongi Slim Hospital | 300 | 2023-11-30 | 2024-06-06 |
| Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS) ExoFlo, Intravenous normal saline - Acute Respiratory Distress Syndrome, ARDS | Phase 3 | Recruiting | Direct Biologics, LLC | 970 | 2022-07-01 | 2026-02-23 |
| Hydrocortisone Use During Peri-operation for Pituitary Adenomas Normal saline, Hydrocortisone - Pituitary Adenoma, Adrenal Insufficiency | Not applicable | Unknown | Peking Union Medical College Hospital | 436 | 2020-11-01 | 2020-11-09 |
| Nitroglycerin for Intra-arterial Chemotherapy in Pediatric Retinoblastoma. Nitroglycerin, Normal saline - Retinoblastoma | Not applicable | Unknown | Seoul National University Hospital | 36 | 2020-09-28 | 2023-11-22 |
| Extracellular Vesicle Infusion Treatment for COVID-19 Associated ARDS ExoFlo, Intravenous normal saline - COVID-19, ARDS | Phase 2 | Completed | Direct Biologics, LLC | 102 | 2020-09-24 | 2024-02-13 |
| Intravenous (IV) Versus Oral Iron Treatment of Iron Deficiency Anemia in the Post-operative Bariatric Surgical Patient Ferumoxytol, Ferrous sulfate, Oral vitamin C - IDA in the Post-bariatric Surgical Patient | Not applicable | Withdrawn | Johns Hopkins University | 2019-08-01 | 2019-09-11 | |
| A Trial of Local Anaesthesia Versus Local Anaesthesia and Conscious Sedation for Hernioplasty Midazolam, Intravenous Normal Saline, Bupivocaine - Inguinal Hernia, Anesthesia, Local | Phase 3 | Unknown | The University of The West Indies | 180 | 2013-12-01 | 2015-05-14 |
| Pilot Trial on Efficacy of Single Dose Perioperative Intravenous Dexamethasone for Pain Relief After Endoscopic Submucosal Dissection intravenous dexamethasone, intravenous normal saline - Early Gastric Cancer or Gastric Adenoma | Not applicable | Unknown | Yonsei University | 50 | 2013-07-01 | 2014-01-15 |
| Efficacy of Intraperitoneal Versus Intravenous Lidocaine for Postcesarean Pain Relief Intravenous normal saline, Intraperitoneal normal saline, Intraperitoneal Lidocaine - Postcesarean Pain Relief | Phase 2 / Phase 3 | Completed | Benha University | 150 | 2013-06-01 | 2016-03-14 |
| Oral Hydration for Mild to Moderate Hyperglycemia in the Emergency Department Oral water, Intravenous normal saline - Hyperglycemia | Phase 1 | Completed | University of Southern California | 80 | 2011-01-01 | 2011-07-25 |
Adrenal Insufficiency (1) · COVID-19 (1) · Depression (1) · Hernia, Inguinal (1) · Hyperglycemia (1) · Pituitary Neoplasms (1) · Post-Dural Puncture Headache (1) · Respiratory Distress Syndrome (1) · Retinoblastoma (1) · Stomach Neoplasms (1)
Direct Biologics, LLC (2) · Benha University (1) · Huazhong University of Science and Technology (1) · Johns Hopkins University (1) · Mongi Slim Hospital (1) · Peking Union Medical College Hospital (1) · Seoul National University Hospital (1) · The University of The West Indies (1) · University of Southern California (1) · Yonsei University (1)
United States (3) · South Korea (2) · China (1) · Jamaica (1) · Tunisia (1)
Bill Arana (2) · Bing Xing, MD (1) · Kimberley E Steele, MD, Ph.D (1) · Wei Lian, MD (1) · Wei Mei, Phd (1)