12 completed, 2 not yet recruiting, 2 unknown, 1 enrolling by invitation. 7 Phase 4, 6 Not applicable, 6 Phase 3.
Follow Intravenous Dexamethasone: new trials by email Literature Review of Intravenous Dexamethasone trials Research Report on Intravenous Dexamethasone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of Intravenous Dexamethasone on the Duration of Motor and Sensory Block Following Spinal Anesthesia With Chloroprocaine Intravenous Dexamethasone, Normal Saline - Spinal Anesthesia, Prolonged Sensory Block | Not applicable | Not yet recruiting | Centre hospitalier de l'Université de Montréal (CHUM) | 60 | 2026-11-01 | 2026-10-08 |
| Intravenous Dexamethasone Added to Dexmedetomidine After Superior Trunk Block Intravenous Dexamethasone, Normal Saline Placebo, Intravenous Dexmedetomidine - Postoperative Pain, Arthroscopic Shoulder Surgery | Phase 4 | Not yet recruiting | Gaziantep City Hospital | 70 | 2026-09-01 | 2026-08-31 |
| The Effect of Dexamethasone Administration Route in Pediatric Brachial Plexus Block perineural dexamethasone, intravenous dexamethasone, 0.2ml/kg 0.2% ropivacaine - Arm | Phase 4 | Completed | Poznan University of Medical Sciences | 90 | 2025-10-01 | 2026-07-30 |
| IV DEXAMETHASONE VS. METHYLPREDNISOLONE IN CHILDREN WITH SEVERE ASTHMA EXACERBATION Intravenous Dexamethasone, Intravenous Methylprednisolone - Status Asthmaticus, Asthma (Diagnosis) | Phase 4 | Completed | Istanbul Medeniyet University | 129 | 2025-09-01 | 2026-07-28 |
| Comparing Pain Relief Between Two Methods of Freezing Injections in Children Having Their Appendix Removed Rectus Sheath Block, Local Anesthetic at the Umbilical Port Site, Intravenous Dexamethasone - Laparoscopic Appendectomy | Not applicable | Enrolling by invitation | University of British Columbia | 32 | 2025-05-01 | 2025-05-16 |
| The Effect of Dexamethasone Administration Route and Local Anesthetic Concentration on Pain, Inflammatory Response, and Neuromonitoring in Children Undergoing Scoliosis Correction perineural Dexamethasone, intravenous Dexamethasone - Scoliosis Idiopathic Adolescent | Phase 4 | Completed | Poznan University of Medical Sciences | 60 | 2025-02-01 | 2026-10-19 |
| Regional and Intravenous Dexamethasone in The Prophylaxis of Rebound Pain After Supraclavicular Block in Upper Limb Surgeries Regional Dexamethasone, Intravenous Dexamethasone - Regional, Intravenous | Not applicable | Completed | Tanta University | 90 | 2023-03-01 | 2025-07-20 |
| The Effect of IV NSAID's and Corticosteroids on Dysphasia and Dysphonia Following ASDF Intravenous Ketorolac, Intravenous Dexamethasone, Placebo - Dysphagia, Dysphonia | Phase 3 | Terminated | University of Nebraska | 33 | 2021-01-02 | 2024-08-23 |
| BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to Ondansetron Granisetron Transdermal Patch, Intravenous Dexamethasone, Ondansetron - Nausea With Vomiting Chemotherapy-Induced | Phase 4 | Recruiting | University of Illinois at Chicago | 90 | 2020-05-14 | 2025-11-12 |
| Effect of Using Azithromycin Versus Placebo With Dexamethasone in Prevention of Post-spinal Nausea and Vomiting. Oral Azithromycin tablet, Intravenous dexamethasone - Post-operative Nausea and Vomiting | Phase 4 | Unknown | Assiut University | 160 | 2019-06-01 | 2019-01-29 |
| Minimal Effective Concentration (EC90) of Ropivacaine Intravenous dexamethasone, Intravenous saline, Perineural ropivacaine - Anesthesia, Conduction, Ropivacaine | Phase 3 | Completed | Centre Hospitalier Universitaire de Besancon | 146 | 2018-10-05 | 2020-12-21 |
| Intravenous Dexamethasone for Ropivacaine Axillary Block intravenous dexamethasone, intravenous placebo, perineural ropivacaine - Postoperative Pain, Anesthesia | Phase 3 | Completed | Centre Hospitalier Universitaire de Besancon | 99 | 2016-12-01 | 2018-01-31 |
| Intravenous Versus Intra-peritoneal Dexamethasone on the Incidence of Postoperative Nausea and Vomiting Intravenous Dexamethasone, Intraperitoneal Dexamesathone - Postoperative Nausea and Vomiting | Not applicable | Completed | Assiut University | 100 | 2016-11-01 | 2018-02-13 |
| Interscalene Block With Low-dose IV vs. Perineural Dexamethasone for Shoulder Arthroscopy Bupivacaine, Perineural dexamethasone, Intravenous dexamethasone - Pain, Shoulder Arthroscopy | Phase 4 | Completed | Hospital for Special Surgery, New York | 128 | 2015-08-01 | 2018-08-29 |
| Dexamethasone Regimens for Prophylaxis of Paclitaxel-associated Hypersensitivity Reaction Intravenous Dexamethasone, Oral Dexamethasone - Hypersensitivity Reaction | Phase 3 | Completed | Department of Medical Services Ministry of Public Health of Thailand | 260 | 2015-02-28 | 2020-10-23 |
| Dexamethasone and Respiratory Function After Mastectomy Intravenous Dexamethasone, intravenous salin water - Respiratory; Disorder, Functional, Impaired | Phase 3 | Completed | Instituto Mexicano del Seguro Social | 120 | 2014-11-01 | 2023-10-03 |
| Pilot Trial on Efficacy of Single Dose Perioperative Intravenous Dexamethasone for Pain Relief After Endoscopic Submucosal Dissection intravenous dexamethasone, intravenous normal saline - Early Gastric Cancer or Gastric Adenoma | Not applicable | Unknown | Yonsei University | 50 | 2013-07-01 | 2014-01-15 |
| Peri-Operative Steroid Management in Patients hydrocortisone, dexamethasone - Pituitary Adenoma, Pituitary Diseases | Not applicable | Completed | Washington University School of Medicine | 43 | 2012-03-01 | 2018-04-11 |
| Effect of Dexamethasone in Postoperative Symptoms After Mastectomy for Breast Cancer intravenous dexamethasone, Homologated placebo. - Postoperative Pain, Postoperative Nausea | Phase 3 | Completed | Instituto Mexicano del Seguro Social | 70 | 2009-06-01 | 2010-05-05 |
Pain, Postoperative (3) · Agnosia (2) · Postoperative Nausea and Vomiting (2) · Asthma (1) · Breast Neoplasms (1) · Deglutition Disorders (1) · Disease (1) · Dysphonia (1) · Forearm Injuries (1) · Hypersensitivity (1) · Pain (1) · Patient Satisfaction (1) · Pituitary Diseases (1) · Pituitary Neoplasms (1) · Scoliosis (1)
Assiut University (2) · Centre Hospitalier Universitaire de Besancon (2) · Instituto Mexicano del Seguro Social (2) · Poznan University of Medical Sciences (2) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · Department of Medical Services Ministry of Public Health of Thailand (1) · Gaziantep City Hospital (1) · Hospital for Special Surgery, New York (1) · Istanbul Medeniyet University (1) · Tanta University (1) · University of British Columbia (1) · University of Illinois at Chicago (1) · University of Nebraska (1) · Washington University School of Medicine (1) · Yonsei University (1)
United States (4) · Canada (2) · Egypt (2) · France (2) · Mexico (2) · Poland (2) · South Korea (1) · Thailand (1) · Turkey (Türkiye) (1)
Alejandro Gonzalez-Ojeda, M.D., Ph.D. (1) · Dr Marut Yanaranop, MD (1) · Julie M. Silverstein, M.D. (1) · Karen Sweiss, PharmD (1) · Kevin Garvin, MD (1) · Malgorzata Reysner, M.D. Ph.D. (1) · Prakash Krishnan, MD (1) · Richard Kahn (1) · Stephan Williams, MD, PhD (1)
PMID 21182781, PMID 28356304, PMID 29889698, PMID 30777900, PMID 33224806, PMID 34002866