8 completed, 2 unknown, 1 terminated, 1 withdrawn. 12 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 12 | Completed 8, Unknown 2, Terminated 1, Withdrawn 1 |
| Phase 2 | 5 | Completed 2, Unknown 2, Withdrawn 1 |
Follow Interleukin-7: new trials by email Literature Review of Interleukin-7 trials Research Report on Interleukin-7
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| 2018-0674 - IL-7 for T-Cell Recovery Post Haplo and CB Transplant - Phase I/II Recombinant Interleukin-7 - Acute Myeloid Leukemia, Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Phase 1 / Phase 2 | Completed | M.D. Anderson Cancer Center | 1 | 2020-09-29 | 2024-10-17 |
| Recombinant Human Interleukin-7 (CYT107) to Promote T-Cell Recovery After Cord Blood Transplantation CYT107 - Umbilical Cord Blood Transplant | Phase 1 / Phase 2 | Withdrawn | M.D. Anderson Cancer Center | 2018-11-01 | 2019-01-10 | |
| Dose Escalation Study of Interleukin-7 (IL-7) and Bitherapy in Asiatic HCV Patients Resistant to Bitherapy Interleukin-7 - Hepatitis C | Phase 1 / Phase 2 | Unknown | Cytheris SA | 15 | 2009-01-01 | 2012-10-18 |
| Dose Escalation Study of Interleukin-7 (IL-7) and Bitherapy in HCV Genotype 1 or 4 Patients Resistant to Bitherapy Alone Interleukin-7 - Hepatitis C | Phase 1 / Phase 2 | Unknown | Cytheris SA | 18 | 2008-07-01 | 2012-10-18 |
| Safety Study of IL-7 in Recipients of a Hemopoietic Stem Cell Transplant Peripheral Blood Stem Cell Transplant CYT107 - Recombinant glycosylated human interleukin 7., rhIL-7 (CYT107) - AML, CML | Phase 1 | Completed | Cytheris, Inc. | 12 | 2008-03-01 | 2012-07-26 |
| Dose Escalation Study of IL-7 and Bi-therapy in HCV Patients Resistant After 12 Weeks of Bi-therapy (ECLIPSE 1) Interleukin-7 - Hepatitis C | Phase 1 / Phase 2 | Completed | Cytheris SA | 10 | 2007-05-01 | 2012-10-18 |
| Safety Study of IL-7 in HIV-infected Patients (Inspire) CYT 107 - HIV Infections, Lymphopenia | Phase 1 | Completed | Cytheris SA | 30 | 2007-05-01 | 2012-10-18 |
| Interleukin-7 in Treating Patients With Metastatic Melanoma or Locally Advanced or Metastatic Kidney Cancer recombinant interleukin-7, gene expression analysis, polymerase chain reaction - Kidney Cancer, Melanoma (Skin) | Phase 1 | Terminated | Cytheris SA | 9 | 2007-05-01 | 2012-10-18 |
| Safety of Interleukin-7 in HIV Infected People Currently Taking Anti-HIV Drugs Recombinant human interleukin-7 - HIV Infections | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 25 | 2005-04-01 | 2021-11-01 |
| Interluekin-7 to Treat HIV-Infected People Receiving Antiretroviral Treatment IL-7 - HIV Infections, HIV | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 20 | 2005-03-01 | 2008-03-04 |
| Interleukin-7 and Vaccine Therapy in Treating Patients With Metastatic Melanoma MART-1 antigen, gp100 antigen, incomplete Freund's adjuvant - Melanoma (Skin) | Phase 1 | Completed | National Cancer Institute (NCI) | 2004-08-01 | 2015-04-30 | |
| Interleukin-7 in Treating Patients With Refractory Solid Tumors recombinant interleukin-7 - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 30 | 2003-04-01 | 2012-03-08 |
HIV Infections (3) · Hepatitis C (3) · Hepatitis, Chronic (3) · Liver Diseases (3) · Virus Diseases (3) · Lymphopenia (2) · Melanoma (2) · Carcinoma, Renal Cell (1) · Graft vs Host Disease (1) · Infections (1) · Kidney Neoplasms (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Leukemia, Myeloid, Acute (1) · Myelodysplastic Syndromes (1) · Myeloproliferative Disorders (1)
Cytheris SA (5) · M.D. Anderson Cancer Center (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · Cytheris, Inc. (1) · National Cancer Institute (NCI) (1) · National Institutes of Health Clinical Center (CC) (1)
United States (8) · France (3) · Italy (3) · Switzerland (2) · Canada (1) · Taiwan (1)
Steven A. Rosenberg, MD, PhD (2) · Tilman Gerlach (2) · Claude Sportes, MD (1) · David Marin, MD (1) · Gheath Al-Atrash (1) · Irini Sereti (1) · Irini Sereti, MD (1) · Marcel van den Brink, MD, PhD (1) · Michael Lederman (1) · Michael M. Lederman, MD (1) · Ronald E. Gress, MD (1) · Wang-Long Chuang, MD (1) · Yves Levy (1)
PMID 16699374, PMID 19380868, PMID 20068111, PMID 23012326, PMID 23589672
R01CA061508 (2)