31 completed. 31 Phase 2, 5 Phase 3, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 31 | Completed 31 |
| Phase 3 | 5 | Completed 5 |
| Phase 1 | 4 | Completed 4 |
Follow Imiquimod: new trials by email Literature Review of Imiquimod trials Research Report on Imiquimod
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intra-dermal With Topical Imiquimod Pretreatment Versus Intra-muscular Hepatitis B Vaccination in IBD Patients Intradermal hepatitis B vaccine with imiquimod, Intramuscular hepatitis B vaccine with aqueous cream - Inflammatory Bowel Diseases, Hepatitis B | Phase 2 / Phase 3 | Completed | The University of Hong Kong | 104 | 2019-08-12 | 2022-05-18 |
| A Study to Evaluate Neoadjuvant Sonidegib Followed by Surgery or Imiquimod in the Management of Basal Cell Carcinoma Sonidegib, Imiquimod, Surgery - Basal Cell Carcinoma, Basal Cell Carcinoma of Skin, Site Unspecified | Phase 2 | Completed | Melanoma Institute Australia | 16 | 2019-07-23 | 2025-12-16 |
| Randomized Clinical Trial Evaluating the Efficacy of Topical Imiquimod in High Grade Cervical Intraepithelial Lesions Control, Imiquimod - High Grade Intraepithelial Neoplasia, Cervix Cancer | Phase 2 | Completed | Barretos Cancer Hospital | 90 | 2018-01-01 | 2021-02-17 |
| Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3) VGX-3100, Imiquimod 5% Cream, CELLECTRA™ 2000 - Vulvar High Grade Squamous Intraepithelial Lesion (HSIL), Vulvar Dysplasia | Phase 2 | Completed | Inovio Pharmaceuticals | 33 | 2017-08-31 | 2023-08-25 |
| Imiquimod and Influenza Vaccine for Immunocompromised Patients Intanza, Mutagrip, Aldara - Influenza Vaccine | Phase 2 | Completed | University of Lausanne Hospitals | 70 | 2016-11-01 | 2017-10-10 |
| iVAC-CLL01: Patient-individualized Peptide Vaccination After First Line Therapy of CLL Peptide Vaccine, Imiquimod - Leukemia, Chronic Lymphatic | Phase 2 | Completed | University Hospital Tuebingen | 56 | 2016-10-05 | 2022-11-28 |
| ID HBV Vaccination With Imiquimod in OBI Imiquimod + ID HBVv, Aqueous + ID HBVv, Imiquimod + IM HBVv - Hepatitis B | Phase 2 / Phase 3 | Completed | The University of Hong Kong | 120 | 2016-10-01 | 2019-10-22 |
| Treatment of High-Grade Pre-Neoplastic Cervical Lesions (CIN 2/3) 9-valent HPV vaccine, Imiquimod - Cervical Intraepithelial Neoplasia, Cervical Dysplasia | Phase 2 | Completed | Yale University | 134 | 2016-07-01 | 2024-05-02 |
| Patient-individualized Peptide Vaccination Based on Tumor-specific Mutations in Children and Young Adults With Primary/Relapsed ALL Individual peptide vaccination with adjuvant GM-CSF and Imiquimod - Primary/Relapsed Acute Lymphoblastic Leukemia (ALL) of Childhood, Adolescents and Young Adults | Phase 1 / Phase 2 | Completed | University Children's Hospital Tuebingen | 30 | 2016-06-01 | 2023-12-04 |
| HBV Vaccine in Renal Failure Patients Intradermal HBVv with imiquimod, Intradermal HBVv with aqueous cream, Intramuscular HBVv with aqueous cream - Renal Failure | Phase 2 / Phase 3 | Completed | The University of Hong Kong | 94 | 2016-01-01 | 2019-10-22 |
| Efficacy and Tolerability of Topical LFX453 for External Genital Warts Investigational Treatment, Aldara - External Genital Warts | Phase 2 | Completed | Novartis Pharmaceuticals | 88 | 2015-05-12 | 2021-01-05 |
| Topical Imiquimod vs. LEEP for Women With Carcinoma In-situ of the Cervix Imiquimod, Loop Electrosurgical Excision Procedure - Cervical Intraepithelial Neoplasia | Phase 2 / Phase 3 | Completed | United States Naval Medical Center, San Diego | 22 | 2015-02-01 | 2017-06-27 |
| Safety and Efficacy Study of SL-701, a Glioma-Associated Antigen Vaccine To Treat Recurrent Glioblastoma Multiforme SL-701; poly-ICLC (polyinosinic-polycytidylic acid stabilized with polylysine and carboxymethyl cellulose), Bevacizumab, SL-701 + GM-CSF - Adult Brain Glioblastoma, Glioblastoma Multiforme | Phase 1 / Phase 2 | Completed | Stemline Therapeutics, Inc. | 74 | 2014-05-01 | 2025-02-03 |
| Combination Vaccine Immunotherapy (DRibbles) for Patients With Definitively-Treated Stage III Non-small Cell Lung Cancer Cyclophosphamide, DRibble vaccine, Imiquimod - Carcinoma, Non-Small-Cell Lung | Phase 2 | Completed | UbiVac | 12 | 2013-07-01 | 2017-07-06 |
| Study With TMX-101 in Patients With Carcinoma In Situ (CIS) Bladder Cancer TMX-101 - Carcinoma in Situ, Non Muscle Invasive Bladder Cancer | Phase 2 | Completed | Telormedix SA | 12 | 2013-02-01 | 2015-02-10 |
| Genomic Markers Before and After Treatment of Actinic Keratosis With Imiquimod 3.75% Cream Imiquimod 3.75% Cream - Actinic Keratosis | Phase 2 | Completed | Icahn School of Medicine at Mount Sinai | 21 | 2013-01-01 | 2021-01-20 |
| Identification of Novel Biomarkers of Cervicovaginal Mucosal Inflammation Imiquimod, Placebo, Nonoxynol-9 - Vaginal Inflammation, Vaginal Infections | Phase 2 | Completed | CONRAD | 20 | 2012-05-01 | 2015-03-31 |
| Toll-like Receptor (TLR) 7 Agonist, Cyclophosphamide, and Radiotherapy for Breast Cancer With Skin Metastases Radiation, Imiquimod, Cyclophosphamide - Breast Cancer, Metastatic Breast Cancer | Phase 1 / Phase 2 | Completed | NYU Langone Health | 31 | 2011-08-19 | 2021-11-18 |
| ITIC (Imiquimod Therapy in Cervical Intraepithelial Neoplasia)-Trial Topical imiquimod therapy - Cervical Intraepithelial Neoplasia | Phase 2 / Phase 3 | Completed | Medical University of Vienna | 60 | 2009-07-01 | 2011-01-24 |
| Imiquimod for Breast Cancer Patients With Chest Wall Recurrence or Skin Metastases Imiquimod - Breast Cancer, Breast Neoplasms | Phase 2 | Completed | NYU Langone Health | 10 | 2009-05-01 | 2015-12-07 |
Showing 20 of 31. Sign in to see all of them.
Keratosis, Actinic (4) · Uterine Cervical Dysplasia (4) · Breast Neoplasms (3) · Hepatitis B (2) · Melanoma (2) · Uterine Cervical Neoplasms (2) · Breast Neoplasms, Male (1) · Carcinoma in Situ (1) · Carcinoma, Basal Cell (1) · Carcinoma, Non-Small-Cell Lung (1) · Colorectal Neoplasms (1) · Condylomata Acuminata (1) · Glioblastoma (1) · HIV Infections (1) · Hemangioma (1)
The University of Hong Kong (3) · Medical University of Vienna (2) · NYU Langone Health (2) · Alliance for Clinical Trials in Oncology (1) · Barretos Cancer Hospital (1) · CONRAD (1) · Cytos Biotechnology AG (1) · Foundation Fader (1) · Graceway Pharmaceuticals, LLC (1) · Icahn School of Medicine at Mount Sinai (1) · Immatics Biotechnologies GmbH (1) · Inovio Pharmaceuticals (1) · MEDA Pharma GmbH & Co. KG (1) · Melanoma Institute Australia (1) · Moberg Pharma AB (1)
United States (15) · Germany (4) · Austria (2) · Hong Kong (2) · Switzerland (2) · Australia (1) · Belgium (1) · Bolivia (1) · Brazil (1) · Bulgaria (1) · Canada (1) · China (1) · Hungary (1) · Latvia (1) · Poland (1)
Sylvia Adams, MD (2) · Addie N Alkhas, MD (1) · Alessandro D Santin, MD (1) · Andrea Mayer-Mokler (1) · Andrea R Thurman, MD (1) · Bernard Fox, PhD (1) · Bobbie S. Gostout, MD (1) · Bruno DO Fonseca, MD (1) · Catherine McCuaig, M.D. (1) · Georg Stingl, Prof. (1) · Ivan FN Hung, MD FRCP (1) · Jeffrey Skolnik, MD (1) · Lupe Salazar (1) · Oriol Manuel, MD (1)
PMID 21907959, PMID 22914404, PMID 11595691, PMID 15863172, PMID 16174242, PMID 16473126, PMID 17655918, PMID 18385498, PMID 18407790, PMID 18801868, PMID 19419474, PMID 19640281, PMID 20556751, PMID 21288852, PMID 21377898, PMID 21530398, PMID 22742517, PMID 22767669, PMID 23042206, PMID 23276555, PMID 23380265, PMID 23489374, PMID 23843155, PMID 24201682, PMID 24264713, PMID 24411029, PMID 28114604, PMID 28341495, PMID 32556176, PMID 33957649, PMID 35546255, PMID 39660140, PMID 40187749
2015 (1), 2016 (1), R01CA138521 (1), R01CA161891 (1), R44CA121612 (1)