9 recruiting, 9 unknown, 6 completed, 4 not yet recruiting. 19 Not applicable, 7 Phase 2, 5 Phase 1, 4 Phase 3.
Follow Hyperthermia: new trials by email Literature Review of Hyperthermia trials Research Report on Hyperthermia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Thermotherapy for Head and Neck Cancer Patients Thermotherapy, Radiotherapy, Concurrent chemoradiation - Head and Neck Cancer, Oropharyngeal Carcinoma | Phase 1 | Recruiting | Erasmus Medical Center | 30 | 2026-09-01 | 2026-09-02 |
| Hyperthermia Safety Study Uses Temperature Management System to Gently Raise Participant's Body Temperature to a Fever-range Level in a Controlled Setting. Hyperthermia - Safety Study | Not applicable | Enrolling by invitation | Marc Abreu | 20 | 2026-09-01 | 2026-09-21 |
| The Sarah Nanotechnology System for Treatment of Advanced Metastatic Solid Tumors Using Hyperthermia. The Sarah Nanotechnology System - intended to deliver thermal energy to malignant cells for the purpose of thermal destruction of these cells in patients with advanced metastatic solid tumors. - Metastatic Solid Tumors, Stage 4 Cancer | Not applicable | Recruiting | New Phase Ltd. | 12 | 2025-12-16 | 2026-05-15 |
| Feasibility of Total Neoadjuvant Treatment With HYPErthermia in Patients With High-risk Extremity and Trunk Soft Tissue Sarcoma (TNT-HYPE) Doxorubicin, Ifosfamide, Dacarbazine - Sarcoma,Soft Tissue | Phase 2 | Recruiting | Swiss Cancer Institute | 24 | 2025-10-27 | 2025-12-30 |
| Modulated Electro-Hyperthermia in Combination With Multimodal Therapy for Locally Advanced Rectal Cancer Hyperthermia - Locally Advanced Rectal Carcinoma | Phase 3 | Recruiting | Shih-Kai Hung | 126 | 2025-09-23 | 2026-01-28 |
| Hyperthermia Combined With Immune Checkpoint Inhibitors in the Treatment of Advanced Gastrointestinal Malignancies With Liver Metastases Hyperthermia, Immunotherapy - Gastrointestinal Cancer, Immunotherapy | Phase 2 | Not yet recruiting | China Medical University, China | 40 | 2025-08-15 | 2025-08-12 |
| Analysis of Hyperthermia as an Adjunctive Treatment to Evidence-based Clinical Intervention in Subjects With Bursitis: a Double-blind Randomized Clinical Trial Hyperthermia, Physical Exercise, Stretching - Bursitis, Hyperthermia | Not applicable | Not yet recruiting | University of Malaga | 120 | 2025-08-01 | 2025-08-01 |
| Analysis of Hyperthermia as an Adjunctive Treatment to Evidence-based Clinical Intervention in Subjects With Plantar Fasciitis: a Double-blind Randomized Clinical Trial Hyperthermia, Physical Exercise, Stretching - Plantar Fascia, Hyperthermia | Not applicable | Not yet recruiting | University of Malaga | 64 | 2025-08-01 | 2025-08-05 |
| Analysis of Hyperthermia as a Complementary Treatment to Evidence-based Clinical Intervention in Subjects With Carpal Tunnel Syndrome: hyperthermia, physical exercise, splint - Carpal Tunnel Syndrome (CTS), Hyperthermia | Not applicable | Not yet recruiting | University of Malaga | 160 | 2025-05-01 | 2025-04-24 |
| Thermotherapy for Locally Advanced Head and Neck Cancer Thermotherapy, radiotherapy - Head and Neck Cancer, Oropharyngeal Carcinoma | Phase 1 | Active not recruiting | Erasmus Medical Center | 2 | 2025-05-01 | 2026-09-02 |
| Hyperthermia With Chemoradiotherapy in Rectal Cancer Hyperthermia, Radiotherapy, Chemotherapy with 5-fluorouracil - Rectal Cancer | Not applicable | Recruiting | University Hospital Tuebingen | 264 | 2024-09-11 | 2026-10-13 |
| Effect of Strontium-90 Brachytherapy Combined With Hyperthermia in the Treatment of Keloid hyperthermia - Keloid | Not applicable | Unknown | Nanjing First Hospital, Nanjing Medical University | 80 | 2024-05-14 | 2024-05-28 |
| Clinical Application of Near-infrared Whole Body Heat Shock Multimodal Technique in Treatment of Castration-resistant Prostate Cancer Immunotherapy, Targeted therapy, Hyperthermia - Metastatic Castration-resistant Prostate Cancer (CRPC) | Phase 2 | Recruiting | Pengyuan Liu | 60 | 2024-01-01 | 2024-02-08 |
| Hyperthermia With Flexible Electrode-typed 2-MHz Device During Radiotherapy for Solid Tumors Hyperthermia, Radiotherapy - Solid Tumor | Not applicable | Unknown | Yonsei Hyperthermia Study Group | 20 | 2022-03-10 | 2022-03-16 |
| Registry Trial to Evaluate the Safety and Efficacy of Hyperthermia in Locally Advanced Cancers Hyperthermia - Locally Advanced Malignant Neoplasm | Unknown | Mahatma Gandhi Institute of Medical Sciences | 500 | 2021-10-18 | 2024-09-19 | |
| Radiotherapy With Hyperthermia in Recurrent and Radiation-Induced Sarcomas Hypofractionated radiotherapy, Hyperthermia, Hypofractionated radiotherapy with boost - Radiation Induced Neoplasms, Radiation-Induced Cancer | Not applicable | Completed | Maria Sklodowska-Curie National Research Institute of Oncology | 20 | 2019-10-23 | 2025-04-30 |
| Hyperthermia and Olaparib in Treating Breast Cancer Patients With Chest Wall Recurrences Olaparib, Hyperthermia Treatment, Questionnaire Administration - Metastatic Malignant Neoplasm in the Chest Wall, Recurrent Breast Carcinoma | Phase 1 | Terminated | Thomas Jefferson University | 3 | 2019-05-20 | 2025-12-22 |
| Hypofractionated Radiotherapy With Hyperthermia in Unresectable or Marginally Resectable Soft Tissue Sarcomas Hypofractionated radiotherapy, Hyperthermia - Sarcoma, Alveolar Soft Part Sarcoma | Phase 2 | Unknown | Maria Sklodowska-Curie National Research Institute of Oncology | 30 | 2018-06-01 | 2021-02-01 |
| Radiation Therapy or Chemoradiation, Interstitial Brachytherapy in Combination With Hyperthermia in Advanced Cervical Cancer Radiation, brachytherapy, Cisplatin - Cervical Cancer | Not applicable | Recruiting | University of Erlangen-Nürnberg Medical School | 999 | 2017-08-01 | 2017-08-15 |
| Organ-preservative Therapy of Bladder Cancer With Radiotherapy or Radiochemotherapy Combined With Hyperthermia Hyperthermia, Radiotherapy, Chemotherapy 5-Fluorouracil - Bladder Cancer | Not applicable | Recruiting | University of Erlangen-Nürnberg Medical School | 1000 | 2017-03-29 | 2024-05-09 |
Showing 20 of 35. Sign in to see all of them.
Hyperthermia (23) · Head and Neck Neoplasms (4) · Prostatic Neoplasms (4) · Sarcoma (4) · Uterine Cervical Neoplasms (4) · Breast Neoplasms (3) · Colonic Neoplasms (3) · Neoplasms (3) · Ovarian Neoplasms (3) · Rectal Neoplasms (3) · Hypopharyngeal Neoplasms (2) · Laryngeal Neoplasms (2) · Lung Neoplasms (2) · Melanoma (2) · Mouth Neoplasms (2)
University of Erlangen-Nürnberg Medical School (6) · Maria Sklodowska-Curie National Research Institute of Oncology (3) · University of Malaga (3) · Erasmus Medical Center (2) · Shin Kong Wu Ho-Su Memorial Hospital (2) · Celsius42 GmbH (1) · China Medical University, China (1) · Dana-Farber Cancer Institute (1) · Fachklinik Hornheide an der Universität Münster (1) · Mahatma Gandhi Institute of Medical Sciences (1) · Marc Abreu (1) · Mark Dewhirst (1) · Medical University of Vienna (1) · Nanjing First Hospital, Nanjing Medical University (1) · New Phase Ltd. (1)
Germany (8) · United States (7) · Poland (4) · Taiwan (3) · China (2) · Netherlands (2) · Austria (1) · India (1) · Switzerland (1)
Michiel Kroesen, MD, Dr. (2) · Oliver Ott, MD (2) · Vratislav Strnad, MD (2) · Angeles Secord, MD (1) · Anurag Singh (1) · Cihan Gani, MD, Prof. Dr. (1) · Elizabeth Jewell, MD (1) · Ellen Jones, MD, PhD (1) · Emanuel Stutz, MD (1) · Feng Wang (1) · I-Chow J. Hsu, MD (1)
PMID 30390114, PMID 33805731, PMID 41702454
P30CA006516 (1), R01CA122276 (1)