8 recruiting, 7 completed, 6 active not recruiting, 4 withdrawn. 14 Phase 2, 8 Phase 3, 3 Not applicable, 3 Phase 1, 1 Phase 4.
Follow Hormone Therapy: new trials by email Literature Review of Hormone Therapy trials Research Report on Hormone Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Adding Surgery and Radiation to the Usual Treatment for HER2-Positive Breast Cancer That Had Already Spread at Diagnosis Biopsy Procedure, Biospecimen Collection, Breast Conservation Treatment - Anatomic Stage IV Breast Cancer AJCC v8, Metastatic HER2-Positive Breast Carcinoma | Phase 3 | Recruiting | SWOG Cancer Research Network | 562 | 2027-03-09 | 2026-10-13 |
| A Vaccine (STEMVAC) With Standard Endocrine-Based Therapy or Chemotherapy for the Treatment of Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer CD105/Yb-1/SOX2/CDH3/MDM2-polyepitope Plasmid DNA Vaccine, Capecitabine, Computed Tomography - Anatomic Stage IV Breast Cancer AJCC v8, Metastatic HER2-Negative Breast Carcinoma | Phase 2 | Recruiting | University of Washington | 40 | 2025-11-17 | 2026-04-06 |
| Ph2 Study for Optimization of Adjunct Systemic Therapy in HER2+ Patients, MolecularPCR Trial Biospecimen Collection, Hormone Therapy, Pembrolizumab - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Phase 2 | Recruiting | M.D. Anderson Cancer Center | 120 | 2025-10-09 | 2026-09-24 |
| Presurgical Phase II Study of Talazoparib in Combination With Enzalutamide in Prostate Cancer ADT, Enzalutamide, Talazoparib - Prostate Cancer | Phase 2 | Recruiting | M.D. Anderson Cancer Center | 30 | 2025-06-03 | 2026-10-19 |
| Metabolic and Physiologic Responses to Hormone Therapy in Transgender and Gender Diverse People hormone therapy - Effects of GAHT, on Skeletal Muscle in TGD | Recruiting | Mayo Clinic | 24 | 2024-01-04 | 2026-08-05 | |
| A Randomized Phase III Trial of Stereotactic Ablative Radiotherapy for Patients With Up to 10 Oligometastases and a Synchronous Primary Tumor. Palliative Radiotherapy, Chemotherapy, Hormone therapy - Metastatic Tumor | Phase 3 | Recruiting | David Palma | 180 | 2023-10-06 | 2025-12-31 |
| Immediate Curative vs Conservative Treatment in Older Men With M0, High-risk Prostate Cancer Radiotherapy or surgery, initial observation, Hormone therapy - Prostate Cancer | Phase 3 | Recruiting | Sven Löffeler | 980 | 2022-11-04 | 2026-09-10 |
| Treatment With Tucatinib in Patients With an Isolated Brain Progression of a Metastatic Breast Cancer Tucatinib, Pertuzumab, Trastuzumab - Metastatic Breast Cancer With a Isolated Brain Progression | Phase 2 | Active not recruiting | UNICANCER | 53 | 2021-12-17 | 2025-11-17 |
| Efficacy and Safety of Bortezomib as First-line Treatment of Acquired TTP Bortezomib Injection - Thrombotic Thrombocytopenic Purpura, Acquired | Phase 4 | Unknown | Peking Union Medical College Hospital | 30 | 2021-12-01 | 2021-11-26 |
| SRS & Abemaciclib w/wo Imlunestrant in the Management of HR+/HER2- Breast CA Brain Metastases Stereotactic Radiosurgery (SRS), Abemaciclib, Endocrine therapy - Brain Metastases, HR+ Metastatic Breast Cancer | Phase 1 / Phase 2 | Recruiting | H. Lee Moffitt Cancer Center and Research Institute | 31 | 2021-11-30 | 2026-09-28 |
| Extremely Hypofractionated Intensity Modulated Stereotactic Body Radiotherapy for the Treatment of Prostate Cancer With Rising PSA After Radical Prostatectomy Hormone Therapy, Stereotactic Body Radiation Therapy - Prostate Adenocarcinoma, Stage IIIB Prostate Cancer American Joint Committee on Cancer (AJCC) v8 | Phase 2 | Active not recruiting | Jonsson Comprehensive Cancer Center | 165 | 2021-06-23 | 2026-07-17 |
| Intermittent Androgen Deprivation Therapy With or Without Stereotactic Body Radiotherapy for Molecularly Identified Hormone Sensitive Oligometastatic Prostate Cancer SBRT, Hormone therapy - Prostate Cancer | Phase 1 / Phase 2 | Active not recruiting | Sunnybrook Health Sciences Centre | 60 | 2020-10-27 | 2026-06-26 |
| Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer, INNOVATE Trial Apalutamide, Biospecimen Collection, Bone Scan - Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8 | Phase 3 | Active not recruiting | NRG Oncology | 586 | 2020-04-16 | 2026-08-17 |
| A Two-Arm Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Subcutaneous Administration of the Fixed-Dose Combination of Pertuzumab and Trastuzumab in Combination With Chemotherapy in Chinese Participants With HER2-Positive Early Breast Cancer Pertuzumab IV, Trastuzumab IV, Pertuzumab and Trastuzumab FDC SC - HER2-positive Early Breast Cancer | Phase 3 | Completed | Hoffmann-La Roche | 200 | 2020-02-05 | 2026-02-20 |
| Neoadjuvant Endocrine Therapy, Palbociclib, Avelumab in Estrogen Receptor Positive Breast Cancer Avelumab, Endocrine therapy, Palbociclib - Breast Cancer | Phase 2 | Active not recruiting | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 33 | 2018-11-13 | 2026-09-24 |
| A Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Subcutaneous Administration of the Fixed-Dose Combination of Pertuzumab and Trastuzumab in Combination With Chemotherapy in Participants With HER2-Positive Early Breast Cancer Cyclophosphamide, Doxorubicin, Docetaxel - Early Breast Cancer | Phase 3 | Completed | Hoffmann-La Roche | 500 | 2018-06-14 | 2024-06-26 |
| The Efficacy of G-CSF Against Adhesion Reformation After Hysteroscopic Adhesiolysis G-CSF, Normal saline, hormone therapy - Intrauterine Adhesion | Not applicable | Unknown | Sir Run Run Shaw Hospital | 240 | 2016-08-01 | 2018-01-05 |
| Clinical Trial Comparing 3-D RT vs. IMRT in Post- Prostatectomy Prostate Cancer Patients 3-D Conformal Radiation Therapy, Intensity Modulated Radiation Therapy, Casodex, Zoladex , Lupron - Prostate Cancer | Phase 2 | Withdrawn | University of Kansas Medical Center | 2015-12-01 | 2016-07-22 | |
| MRI and Gene Expression in Diagnosing Patients With Ductal Breast Cancer In Situ Magnetic Resonance Imaging, Therapeutic Conventional Surgery, Therapeutic Surgical Procedure - Ductal Breast Carcinoma In Situ | Not applicable | Active not recruiting | ECOG-ACRIN Cancer Research Group | 368 | 2015-03-25 | 2025-12-19 |
| Cytoreductive Prostatectomy in Treating Patients With Newly Diagnosed, Metastatic Prostate Cancer Robotic Assisted Radical Prostatectomy, Conventional open retropubic radical prostectomy, Laboratory Biomarker Analysis - Metastatic Prostate Carcinoma, Metastatic Prostatic Adenocarcinoma | Phase 1 | Completed | Rutgers, The State University of New Jersey | 26 | 2015-03-06 | 2021-04-08 |
Showing 20 of 28. Sign in to see all of them.
Prostatic Neoplasms (8) · Breast Neoplasms (6) · Carcinoma, Ductal, Breast (2) · Carcinoma, Lobular (2) · Neoplasms, Hormone-Dependent (2) · Atherosclerosis (1) · Brain Neoplasms (1) · Carcinoma, Intraductal, Noninfiltrating (1) · Carcinoma, Islet Cell (1) · Cardiovascular Diseases (1) · Coronary Artery Disease (1) · Gastrinoma (1) · Glucagonoma (1) · Gynatresia (1) · Insulinoma (1)
M.D. Anderson Cancer Center (3) · Hoffmann-La Roche (2) · Intarcia Therapeutics (2) · Burzynski Research Institute (1) · David Palma (1) · ECOG-ACRIN Cancer Research Group (1) · Eastern Cooperative Oncology Group (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Jonsson Comprehensive Cancer Center (1) · Mayo Clinic (1) · NRG Oncology (1) · Peking Union Medical College Hospital (1) · Robert H. Lurie Cancer Center (1) · Rutgers, The State University of New Jersey (1) · SWOG Cancer Research Network (1)
United States (19) · Canada (5) · China (3) · Russia (3) · Ukraine (3) · France (2) · Argentina (1) · Belgium (1) · Brazil (1) · Bulgaria (1) · Czechia (1) · Denmark (1) · Finland (1) · Germany (1) · Italy (1)
Amado Zurita-Saavedra, MD (1) · Amar Kishan (1) · Angela M Fonseca, PhD (1) · Anne-Claire Hardy-Bessard, MD (1) · Cesar A. Santa-Maria, MD, MSCI (1) · Claudia LM Forjaz, PhD (1) · Constance Lehman (1) · Decio Mion Jr, PhD (1) · Edith Perez, MD (1) · Heather Han, MD (1) · Howard N. Hodis, M.D. (1) · Isaac Kim (1) · Kamran A Ahmed, MD (1) · Kyle Holen, MD (1)
PMID 19996872, PMID 25405497, PMID 27028912, PMID 27421538, PMID 30272234, PMID 30653209, PMID 31362877, PMID 31849202, PMID 32925623, PMID 33357420, PMID 34736575, PMID 35147195, PMID 35526057, PMID 38421243, PMID 38469686, PMID 39244532, PMID 39980346, PMID 40167440, PMID 40608342, PMID 41100122
2017 (1), P30CA016672 (1), P30CA072720 (1), R01AG024154 (1), U10CA037403 (1), U10CA180868 (1), U10CA180888 (1), UG1CA189828 (1)