2 completed, 2 recruiting, 1 not yet recruiting, 1 terminated. 7 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 2, Recruiting 2, Not yet recruiting 1, Terminated 1, Unknown 1 |
| Phase 3 | 1 | Completed 1 |
Follow GLP-1 receptor agonist: new trials by email Literature Review of GLP-1 receptor agonist trials Research Report on GLP-1 receptor agonist
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating the Impact of GLP-1 Receptor Agonists With Total Neoadjuvant Therapy in Rectal Cancer GLP-1 receptor agonist, Total neoadjuvant therapy (TNT) - Rectal Cancer Patients, Obesity &Amp; Overweight | Phase 2 | Not yet recruiting | St. James's Hospital, Ireland | 42 | 2026-04-01 | 2026-01-02 |
| Bone Metabolism in 12-21 Year Olds Undergoing Glucagon Like Peptide (GLP)-1 Receptor Agonist Therapy GLP-1 receptor agonist, Lifestyle intervention - Obesity in Children, Bone Strength | Phase 2 | Recruiting | University of Virginia | 120 | 2025-07-31 | 2026-04-17 |
| GLP-1 Analogue in Preventing Progression of Small Vessel Disease (GAPP-SVD) GLP-1 receptor agonist - Cerebral Small Vessel Disease | Phase 2 | Recruiting | Chinese University of Hong Kong | 110 | 2022-05-25 | 2026-06-05 |
| Effect of GLP-1 Receptor Agonists on Trabecular Bone Score GLP-1 receptor agonist - Osteoporosis, Postmenopausal, Diabetes Mellitus, Type 2 | Phase 2 | Terminated | University of Mississippi Medical Center | 5 | 2021-11-09 | 2025-06-13 |
| Treating PCOS With Semaglutide vs Active Lifestyle Intervention Semaglutide 3mg and 7mg [Rybelsus], Weight loss diet - PCOS, Adolescent Obesity | Phase 2 / Phase 3 | Completed | University of Colorado, Denver | 60 | 2019-05-03 | 2025-11-25 |
| The Effect of GLP-1 Receptor Agonist on Cerebral Blood Flow Velocity in Non-stroke Volunteers Byetta, Isotonic saline - Stroke | Phase 2 | Completed | Christina Kruuse | 30 | 2016-08-01 | 2017-02-07 |
| The Effect of GLP-1 Receptor Agonist on Cerebral Blood Flow Velocity in Stroke Byetta, Normosaline - Ischemic Stroke | Phase 2 | Unknown | Christina Kruuse | 30 | 2016-08-01 | 2023-03-03 |
Ischemic Stroke (2) · Obesity (2) · Pediatric Obesity (2) · Cerebral Small Vessel Diseases (1) · Cerebrovascular Disorders (1) · Diabetes Mellitus, Type 2 (1) · Insulin Resistance (1) · Non-alcoholic Fatty Liver Disease (1) · Osteoporosis, Postmenopausal (1) · Overweight (1) · Stroke (1)
Christina Kruuse (2) · Chinese University of Hong Kong (1) · St. James's Hospital, Ireland (1) · University of Colorado, Denver (1) · University of Mississippi Medical Center (1) · University of Virginia (1)
United States (3) · Denmark (2) · China (1) · Hong Kong (1)
Bonaventure Yiu Ming Ip, MBChB, PhD (1) · Christina R Kruuse, MD, PhD (1) · Christina R Kruuse, MD,PhD (1) · Madhusmita Misra, MD, MPH (1) · Melanie Cree-Green, MD, PhD (1) · Michael Kelly, MB BAO BCH PHD FRCSI (1) · Vishnu V Garla, MD (1) · Zhen Wang, MD (1)
PMID 32923389, PMID 33567185, PMID 35565381, PMID 36294412, PMID 36636739, PMID 37085291, PMID 38888262, PMID 38893212, PMID 38967919, PMID 39093546, PMID 40140925, PMID 40285503, PMID 40437949, PMID 41806363, PMID 42014131
2016 (2), R01DK120612 (1), R01HD118635 (1)