Glepaglutide: Clinical Trials

7 completed, 1 recruiting. 5 Phase 3, 3 Phase 1.

By phase and status

Phase	Trials	Status
Phase 3	5	Completed 4, Recruiting 1
Phase 1	3	Completed 3

Follow Glepaglutide: new trials by email Literature Review of Glepaglutide trials Research Report on Glepaglutide

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBS Glepaglutide, Placebo - Short Bowel Syndrome	Phase 3	Recruiting	Zealand Pharma	90	2026-02-11	2026-09-29
The Long-term Effect on Intestinal Absorption and Safety of Treatment With Glepaglutide in Patients With Short Bowel Syndrome Glepaglutide - Short Bowel Syndrome	Phase 3	Completed	Zealand Pharma	12	2021-08-10	2024-11-22
Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS - Extension Trial Glepaglutide - Short Bowel Syndrome	Phase 3	Completed	Zealand Pharma	84	2021-06-16	2026-09-08
A Bridging Trial to Compare the PK Profile When Glepaglutide is Administered Via Vial/Syringe Versus Autoinjector. Glepaglutide - Healthy	Phase 1	Completed	Zealand Pharma	85	2020-03-04	2021-07-14
Pharmacokinetic Profile of Glepaglutide After a Single Injection in Subjects With Varying Degrees of Renal Function Glepaglutide - Renal Impairment	Phase 1	Completed	Zealand Pharma	16	2019-12-10	2020-11-18
Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS glepaglutide - Short Bowel Syndrome	Phase 3	Completed	Zealand Pharma	150	2019-05-07	2026-09-08
Efficacy And Safety Evaluation of Glepaglutide in Treatment of Short Bowel Syndrome (SBS) glepaglutide, Placebo - Short Bowel Syndrome	Phase 3	Completed	Zealand Pharma	106	2018-10-04	2025-07-17
Trial to Evaluate the PK Profile of Glepaglutide (ZP1848) After a Single IV and After Multiple SC Injections in Healthy Subjects Glepaglutide - Healthy Subjects	Phase 1	Completed	Zealand Pharma	75	2017-09-04	2017-12-22

Conditions studied

Short Bowel Syndrome (5)  ·  Digestive System Diseases (1)  ·  Gastrointestinal Diseases (1)  ·  Intestinal Diseases (1)  ·  Intestinal Failure (1)  ·  Malabsorption Syndromes (1)  ·  Pathologic Processes (1)  ·  Postoperative Complications (1)  ·  Renal Insufficiency (1)  ·  Syndrome (1)

Sponsors

Zealand Pharma (8)

Countries

Denmark (5)  ·  Netherlands (5)  ·  Poland (5)  ·  United States (5)  ·  Belgium (4)  ·  France (4)  ·  Germany (4)  ·  United Kingdom (3)  ·  Canada (2)  ·  Hungary (2)  ·  Austria (1)  ·  Finland (1)  ·  Italy (1)  ·  Norway (1)  ·  Spain (1)

Top investigators

Stine Just Maarbjerg, PhD (1)

Results publications

PMID 36323988, PMID 36811175, PMID 39708985

NIH funding

2019 (1)