3 not yet recruiting, 1 active not recruiting, 1 completed, 1 recruiting. 7 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Not yet recruiting 3, Active not recruiting 1, Completed 1, Recruiting 1, Withdrawn 1 |
Follow GDMT: new trials by email Literature Review of GDMT trials Research Report on GDMT
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| TEER In dynaMic sEvere Functional Mitral Regurgitation (TIMER) TEER, GDMT - Mitral Regurgitation Functional | Not applicable | Not yet recruiting | Sun Yat-sen University | 540 | 2027-01-01 | 2026-09-04 |
| PCI With GDMT Versus GDMT Alone for Patients With Ischemic Cardiomyopathy and Reduced LVEF Percutaneous coronary intervention, Guideline-directed medical therapy - Heart Failure With Reduced Ejection Fraction, Coronary Artery Disease | Not applicable | Not yet recruiting | Nanjing First Hospital, Nanjing Medical University | 1154 | 2026-12-30 | 2026-05-28 |
| Pulmonary Artery Denervation for Heart Failure With Preserved Left Ventricular Ejection Fraction PADN, Sham procedure, GDMT - Heart Failure With Preserved Ejection Fraction | Not applicable | Not yet recruiting | Nanjing First Hospital, Nanjing Medical University | 310 | 2026-12-30 | 2026-05-27 |
| Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure CardioMEMS HF System, HeartMate 3 Left Ventricular Assist System, Guideline Medical Directed Therapy - Heart Failure, Heart Diseases | Not applicable | Recruiting | Abbott Medical Devices | 850 | 2024-12-13 | 2026-06-10 |
| Clinical Efficacy of Early Left Bundle Branch Pacing for Cardiac Resynchronization Therapy LBBP+GDMT, GDMT - Heart Failure, Left Bundle Branch Pacing | Not applicable | Active not recruiting | Fu Wai Hospital, Beijing, China | 36 | 2023-06-26 | 2026-03-31 |
| Randomized Evaluation and Verification of Ventricular Enhancement Revivent TC Ventricular Enhancement System, GDMT - Ischemic Cardiomyopathy, Heart Failure | Not applicable | Withdrawn | BioVentrix | 2020-01-01 | 2025-04-10 | |
| Thoracic Epidural Anesthesia Reduces Mortality and Rehospitalization for Patients With Heart Failure With Reduced Ejection Fraction TEA plus GDMT, GDMT - Heart Failure With Reduced Ejection Fraction, Thoracic Epidural Anesthesia | Not applicable | Completed | First Affiliated Hospital of Harbin Medical University | 1840 | 2013-07-01 | 2024-03-13 |
Heart Failure (3) · Cardiovascular Diseases (1) · Coronary Artery Disease (1) · Heart Diseases (1) · Hypertension, Pulmonary (1)
Nanjing First Hospital, Nanjing Medical University (2) · Abbott Medical Devices (1) · BioVentrix (1) · First Affiliated Hospital of Harbin Medical University (1) · Fu Wai Hospital, Beijing, China (1) · Sun Yat-sen University (1)
China (4) · Germany (2) · Austria (1) · Czechia (1) · Denmark (1) · Italy (1) · Netherlands (1) · Saudi Arabia (1) · United States (1)
Shao-Liang Chen, MD (2) · Kelly O'Connell, PhD (1) · Stefan Anker, MD (1) · Volkmar Falk, MD (1) · Xiaohan Fan, PhD (1)