3 terminated, 2 completed, 1 suspended. 6 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Terminated 3, Completed 2, Suspended 1 |
| Phase 2 | 1 | Completed 1 |
Follow fluoromisonidazole: new trials by email Literature Review of fluoromisonidazole trials Research Report on fluoromisonidazole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tumor Hypoxia and Proliferation in Patients With High-Grade Glioma 18F-FMISO PET, 18F-FLT PET - Glioma | Phase 1 | Suspended | Weill Medical College of Cornell University | 8 | 2021-02-01 | 2026-01-27 |
| FMISO PET/CT Imaging Trial for Assessing Hypoxia in Soft Tissue Sarcomas 18F-FMISO - Soft Tissue Sarcoma | Phase 1 | Terminated | University of Pennsylvania | 5 | 2019-02-01 | 2021-03-18 |
| Pilot Study of 18F-FMISO PET/CT and MRI Imaging to Explore Tissue Hypoxia and Arteriovenous Shunting in Subjects With Recurrent Glioblastoma Before and After Bevacizumab Treatment [18F]fluoromisonidazole, Bevacizumab, positron emission tomography (PET/CT). - Recurrent Glioblastoma | Phase 1 | Terminated | Abramson Cancer Center at Penn Medicine | 2 | 2018-04-18 | 2020-02-17 |
| Assessment of Primary and Metastatic Brain Tumor Hypoxia With Fluoromisonidazole, FDG and Water [18F]fluoro-2-deoxy-D-glucose (FDG), 1H-1-(3-[18F]-fluoro-2-hydroxy-propyl)-2-nitro-imidazole [18F]-fluoromisonidazole, [15O]water - Brain Cancer | Phase 1 | Terminated | University of Utah | 2 | 2013-03-27 | 2024-10-01 |
| Clinical Evaluation of the New Hypoxia Imaging Agent HX4 [F-18] FMISO, [F-18] HX4 - Head and Neck Cancer, Lung Cancer | Phase 1 / Phase 2 | Completed | Siemens Molecular Imaging | 12 | 2009-06-01 | 2012-09-25 |
| PR104 and G-CSF in Treating Patients With Solid Tumors filgrastim, PR104, F-18-fluoromisonidazole - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | Proacta, Incorporated | 5 | 2008-02-01 | 2011-06-01 |
Glioblastoma (2) · Glioma (2) · Brain Neoplasms (1) · Head and Neck Neoplasms (1) · Hypoxia (1) · Liver Neoplasms (1) · Lung Neoplasms (1) · Meningioma (1) · Neoplasms (1) · Sarcoma (1)
Abramson Cancer Center at Penn Medicine (1) · Proacta, Incorporated (1) · Siemens Molecular Imaging (1) · University of Pennsylvania (1) · University of Utah (1) · Weill Medical College of Cornell University (1)
United States (5) · China (1) · New Zealand (1)
Jeffrey Yap, PhD (1) · Sadek Nehmeh, PhD (1) · Seyed Ali Nabavizadeh, MD (1) · Yi Hui Guan, MD (1)