3 completed, 1 terminated. 4 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 3, Terminated 1 |
| Phase 1 | 2 | Completed 1, Terminated 1 |
Follow flt3 ligand protein: new trials by email Literature Review of flt3 ligand protein trials Research Report on flt3 ligand protein
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| FLT3 Ligand, CD40 Agonist Antibody, and Stereotactic Radiotherapy FLT3 Ligand (CDX-301), anti-CD40 antibody (CDX-1140), SBRT - Non Small Cell Lung Cancer, Lung Cancer | Phase 1 / Phase 2 | Terminated | Albert Einstein College of Medicine | 5 | 2021-01-01 | 2024-02-28 |
| A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, Recombinant Flt3 Ligand - Cutaneous Melanoma, Melanoma | Phase 2 | Completed | National Cancer Institute (NCI) | 60 | 2014-04-09 | 2021-11-16 |
| Peripheral Stem Cell Transplantation in Treating Patients With Breast Cancer or Hematologic Cancer filgrastim, recombinant flt3 ligand, recombinant human thrombopoietin - Breast Cancer, Leukemia | Phase 1 / Phase 2 | Completed | Northwestern University | 1999-11-01 | 2012-06-06 | |
| flt3L With or Without Vaccine Therapy in Treating Patients With Metastatic Melanoma or Renal Cell Cancer flt3 ligand, gp100 antigen, MART-1 antigen - Stage IV Melanoma, Stage IV Renal Cell Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 1998-02-01 | 2024-03-04 |
Melanoma (2) · Breast Neoplasms (1) · Breast Neoplasms, Male (1) · Burkitt Lymphoma (1) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Renal Cell (1) · Hodgkin Disease (1) · Immunoblastic Lymphadenopathy (1) · Intraocular Lymphoma (1) · Leukemia (1) · Leukemia, Biphenotypic, Acute (1) · Leukemia, Large Granular Lymphocytic (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative (1) · Leukemia, Myelomonocytic, Chronic (1)
National Cancer Institute (NCI) (2) · Albert Einstein College of Medicine (1) · Northwestern University (1)
United States (4)
Jane N. Winter, MD (1) · Nina Bhardwaj (1) · Patrick Hwu (1)
P30CA015704 (1), U01CA154967 (1)