13 completed, 6 recruiting, 2 active not recruiting, 2 unknown. 18 Not applicable, 4 Phase 2, 3 Phase 1, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 18 | Completed 9, Recruiting 5, Active not recruiting 2, Terminated 1, Unknown 1 |
| Phase 2 | 4 | Completed 3, Recruiting 1 |
| Phase 1 | 3 | Completed 2, Unknown 1 |
| Early Phase 1 | 1 | Completed 1 |
Follow Fiber: new trials by email Literature Review of Fiber trials Research Report on Fiber
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients Dietary Fiber, Enema Administration, Loperamide Hydrochloride - Low Anterior Resection Syndrome, Rectal Carcinoma | Not applicable | Recruiting | Ohio State University Comprehensive Cancer Center | 80 | 2027-02-15 | 2026-10-06 |
| Trial Evaluating Nutritional Fiber in Digestive Symptoms of Endometriosis Fiber, Placebo - Endometriosis, Microbiome Dysbiosis | Not applicable | Recruiting | LOAM Science | 140 | 2026-10-01 | 2026-10-22 |
| Dietary Fiber to Induce Gut Microbiota-mediated Response to Immunotherapy in Melanoma. Dried chicory roots, Placebo - Melanoma (Skin) Stage IV, Melanoma (Skin Cancer) | Phase 2 | Recruiting | Radboud University Medical Center | 70 | 2026-07-31 | 2026-07-27 |
| This Study Aims to Evaluate the Safety and Efficacy of Fiber Supplementation on Constipation in Neurologically Impaired Children Using Rectal Wall Thickness Measurement by Ultrasound. Psyllium Husk, Fiber - Constipation, Neurologically Impaired | Not applicable | Active not recruiting | Ain Shams University | 60 | 2025-11-10 | 2026-08-03 |
| Effect of Fiber Supplementation on the Need for Medication With Gestational Diabetes Fiber - Gestational Diabetes Mellitus (GDM) | Not applicable | Recruiting | Eastern Virginia Medical School | 110 | 2025-02-24 | 2025-03-10 |
| Effects of Goji vs. Fiber on Macular Degeneration Goji berry, Fiber - Age-Related Macular Degeneration | Not applicable | Recruiting | University of California, Davis | 60 | 2024-04-29 | 2026-07-17 |
| Fiber Tolerance Study Fiber - Gastrointestinal Tolerance of Dietary Fiber | Early Phase 1 | Completed | Nutricia Research | 43 | 2023-10-04 | 2024-02-06 |
| Fiber's Utilization for Energy and Life Fiber, Control - Diet Habit | Not applicable | Unknown | University of Illinois at Urbana-Champaign | 19 | 2023-05-13 | 2023-12-06 |
| Impact of Dietary Fiber Supplementation on Colonic Microbiome Dietary Fiber, Proctoscopy or anoscopy with Biopsy, Colonoscopy - Benign Colorectal Neoplasm, Non-Neoplastic Anal Disorder | Not applicable | Recruiting | OHSU Knight Cancer Institute | 120 | 2023-04-01 | 2026-01-15 |
| Maternal & Offspring Microbiome Study Fiber, Fermented Foods - Pregnancy Related, Microbiome | Not applicable | Active not recruiting | Stanford University | 135 | 2022-01-12 | 2026-04-06 |
| Fiber and Fish Oil Supplements for the Prevention of Colorectal Cancer Dietary Fiber, Fish Oil, Comparator - Healthy Subject | Not applicable | Completed | Fred Hutchinson Cancer Center | 38 | 2021-01-05 | 2024-09-27 |
| FMT and Fiber in Patients With Metabolic Syndrome Fecal Microbial Transplant, Fiber, Cellulose - Obesity, Metabolic Syndrome | Phase 2 | Completed | University of Alberta | 68 | 2018-07-01 | 2020-05-05 |
| Kiwifruit, Prunes, & Fiber for Abdominal and Bowel Symptoms in US Patients With Chronic Constipation Kiwifruit, Fiber, Prunes - Chronic Constipation | Not applicable | Completed | University of Michigan | 78 | 2018-06-11 | 2019-10-17 |
| The Effect of Caffeine on the Narcoleptic Patients Vivarin, Fiber - Narcolepsy | Phase 1 / Phase 2 | Completed | King Saud University | 16 | 2016-10-01 | 2019-03-01 |
| Fiber and Cardiovascular Risk Factors fiber - Cardiovascular Risk Factor | Not applicable | Completed | Isfahan University of Medical Sciences | 75 | 2016-01-01 | 2019-09-20 |
| Fiber and Water Improve Bowel Habit in Humans Fiber, Fiber and Water - Dietary Habits, Bowel Dysfunction | Phase 1 / Phase 2 | Completed | Universidade de Passo Fundo | 20 | 2015-08-01 | 2016-07-20 |
| Mealtime Walking Study to Improve Postprandial Metabolic Response 15-minute walk at preferred walking speed., Fiber, control - PreDiabetes, Postprandial Hyperglycemia | Not applicable | Completed | Arizona State University | 10 | 2014-09-17 | 2021-07-23 |
| Constipation Fiber Trial Fiber, Placebo - Functional Constipation in Children | Not applicable | Completed | Warren Bishop | 60 | 2012-06-01 | 2017-09-28 |
| Fiber Health Benefits Fiber, Placebo (low fiber bar) - Healthy | Not applicable | Completed | Warren Bishop | 100 | 2012-04-01 | 2017-09-28 |
| Study of Digestive Tolerance of Orange Juice With Fibers Fiber, Placebo - Digestive Alteration [PE] | Phase 1 | Unknown | University of Sao Paulo | 200 | 2010-10-01 | 2011-01-25 |
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Metabolic Syndrome (3) · Obesity (3) · Diabetes Mellitus (2) · Feeding Behavior (2) · Body Weight (1) · Cardiovascular Diseases (1) · Colitis (1) · Colitis, Microscopic (1) · Constipation (1) · Diabetes, Gestational (1) · Diarrhea (1) · Disorders of Excessive Somnolence (1) · Endometriosis (1) · Glucose Metabolism Disorders (1) · Hyperglycemia (1)
Stanford University (2) · Warren Bishop (2) · Ain Shams University (1) · Arizona State University (1) · Eastern Virginia Medical School (1) · Fred Hutchinson Cancer Center (1) · German Institute of Human Nutrition (1) · Isfahan University of Medical Sciences (1) · King Saud University (1) · LOAM Science (1) · Norwegian University of Science and Technology (1) · Nutricia Research (1) · OHSU Knight Cancer Institute (1) · Ohio State University Comprehensive Cancer Center (1) · Radboud University Medical Center (1)
United States (13) · Netherlands (2) · Brazil (1) · Canada (1) · Egypt (1) · Germany (1) · Norway (1) · Saudi Arabia (1)
Warren Bishop, MD (2) · Alessandra C Gasior, DO (1) · Alice H Lichtenstein, D.Sc. (1) · Andreas FH Pfeiffer, Prof. (1) · Angela M Zivkovic, PhD (1) · Bryce Jarman, PhD (1) · Christopher D Garnder, PhD (1) · Dan L Waitzberg, MD PhD (1) · Fernando Fornari, Professor (1) · Glenn Yiu, MD, PhD (1) · Jerri Waller, MD (1) · Johanna Lampe (1) · Karen Madsen, PhD (1) · Mona S Aldosari, Masteral (1) · Per G Farup, PhD (1)
PMID 27604773, PMID 28202475, PMID 28903959, PMID 29492637, PMID 32215834, PMID 32553145, PMID 34074830, PMID 35603590, PMID 37870148, PMID 39900290, PMID 41461276, PMID 41624204, PMID 42231910
R01DK073321 (1), R21CA245456 (1)