6 completed, 3 unknown, 1 recruiting. 10 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 10 | Completed 6, Unknown 3, Recruiting 1 |
Follow Esketamine: new trials by email Literature Review of Esketamine trials Research Report on Esketamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Personalized DBS Targeting for Treating Depression Deep Brain Stimulation(DBS), Esketamine - Treatment-resistant Depression (TRD) | Early Phase 1 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 5 | 2025-01-05 | 2026-04-27 |
| The Effect of Subclinical Dose of Ketamine on Early Postoperative Pain Sensitivity in Patients Undergoing Salpingectomy esketamine - Ectopic Pregnancy | Early Phase 1 | Completed | Fujian Provincial Hospital | 84 | 2024-08-24 | 2026-02-11 |
| Effect of Esketamine on Reducing Postoperative Anxiety and Depression in Adolescent Patients Esketamine - Anxiety-depression | Early Phase 1 | Unknown | Henan Provincial People's Hospital | 200 | 2023-10-10 | 2023-10-10 |
| Single-dose Effects of Ayahuasca Compared to Esketamine on Experimentally Induced Pain Ayahuasca, Esketamine 0.2 mg/kg - Healthy Adult Participants | Early Phase 1 | Completed | University of Sao Paulo | 20 | 2023-06-01 | 2026-11-02 |
| Esketamine Induction Intubation in ICU Patients. Esketamine Hydrochloride 28 Mg in 0.2 mL NASAL SOLUTION [Spravato], midazolam, fentanyl - Critically Ill Patients | Early Phase 1 | Completed | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 80 | 2022-08-27 | 2026-07-21 |
| The Effects of Subanesthetic S-ketamine on Postoperative Delirium and Cognitive Function in the Elderly Undergoing Non-cardiac Thoracic Surgery S-ketamine, Dexmedetomidine - Postoperative Delirium, Elderly Patients | Early Phase 1 | Completed | Affiliated Cancer Hospital & Institute of Guangzhou Medical University | 520 | 2022-06-10 | 2026-05-01 |
| Different Dose of Esketamine Inhibiting Response to Laryngeal Mask Airway Insertion Esketamine 0.2mg/kg, Esketamine 0.3mg/kg - Anesthesia | Early Phase 1 | Completed | Aerospace Center Hospital | 58 | 2022-05-01 | 2024-04-17 |
| The Effectiveness and Safety of Esketamine in Modified Electroconvulsive Therapy Esketamine, Saline - Esketamine, ECT | Early Phase 1 | Unknown | First Affiliated Hospital of Chongqing Medical University | 396 | 2021-08-01 | 2021-07-20 |
| Effects of Small-dose S-ketamine on Anesthesia-induced Atelectasis in Anesthetized Patients Accessed by Pulmonary Ultrasound S-ketamine, normal saline group - Atelectasis | Early Phase 1 | Unknown | Beijing Tiantan Hospital | 100 | 2021-03-01 | 2021-02-09 |
| S-ketamin Premedication in Pediatric EENT Surgery S-ketamine 0.3, S-ketamine 0.5, S-ketamine 2 - Emotions, Separation Anxiety | Early Phase 1 | Completed | Eye & ENT Hospital of Fudan University | 320 | 2021-03-01 | 2022-04-27 |
Anxiety, Separation (1) · Depression (1) · Depressive Disorder, Treatment-Resistant (1) · Emergence Delirium (1) · Pain, Procedural (1) · Pregnancy, Ectopic (1) · Pulmonary Atelectasis (1)
Aerospace Center Hospital (1) · Affiliated Cancer Hospital & Institute of Guangzhou Medical University (1) · Beijing Tiantan Hospital (1) · Eye & ENT Hospital of Fudan University (1) · First Affiliated Hospital of Chongqing Medical University (1) · Fujian Provincial Hospital (1) · Henan Provincial People's Hospital (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1) · University of Sao Paulo (1)
China (6) · Brazil (1)
Hui Qiao, M.D. (1) · Jiancheng Zhang, MD, PhD (1) · Yihua Li, PhD (1)
PMID 34608328, PMID 35914911, PMID 37730990, PMID 38238838, PMID 39263280, PMID 39972022