15 completed. 15 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 15 | Completed 15 |
| Phase 1 | 3 | Completed 3 |
Follow epothilone B: new trials by email Literature Review of epothilone B trials Research Report on epothilone B
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Patupilone (EPO 906) in Patients With Recurrent or Progressive Glioblastoma Patupilone - Recurrent Glioblastoma Planned for Reoperation | Phase 1 / Phase 2 | Completed | University of Zurich | 9 | 2008-07-01 | 2011-09-15 |
| Study of Patupilone in Prostate Cancer Patients Who Progress After Hormone Therapy and Docetaxel Chemotherapy Patupilone - Hormone Refractory Prostate Cancer | Phase 2 | Completed | British Columbia Cancer Agency | 73 | 2007-02-01 | 2010-11-05 |
| Epothilone B in Treating Patients With CNS Metastases From Breast Cancer epothilone B - Breast Cancer, Metastatic Cancer | Phase 2 | Completed | David Peereboom, MD | 55 | 2007-01-01 | 2014-02-28 |
| Efficacy and Safety of Patupilone in Men (≥18 Years) With Metastatic Hormone Refractory Prostate Cancer Patupilone, prednisone, docetaxel - Metastatic Hormone Refractory Prostate Cancer | Phase 2 | Completed | Novartis Pharmaceuticals | 185 | 2006-09-01 | 2020-12-17 |
| Patupilone Activity in Advanced/Metastatic Hepatocellular Carcinoma Patupilone - Hepatocellular Carcinoma | Phase 2 | Completed | Novartis Pharmaceuticals | 25 | 2006-01-01 | 2017-02-07 |
| Study of Patupilone in Patients With Brain Metastasis From Non-small Cell Lung Cancer Patupilone - Brain Metastasis, Non-small Cell Lung Cancer | Phase 2 | Completed | Novartis Pharmaceuticals | 50 | 2005-11-16 | 2021-02-21 |
| Phase I/II Study of Celebrex and EPO906 in Patients With Metastatic Colorectal Cancer EPO906, Celecoxib - Colon Cancer, Colorectal Cancer | Phase 1 / Phase 2 | Completed | University of Southern California | 75 | 2004-10-12 | 2026-05-28 |
| Dose Escalating Study of the Safety and Efficacy of Patupilone, q3w, in Patients With Non-small Cell Lung Cancer Patupilone - Carcinoma, Non-Small-Cell Lung | Phase 1 / Phase 2 | Completed | Novartis Pharmaceuticals | 89 | 2003-08-01 | 2014-02-05 |
| EPO906 in Carcinoid and Other Neuroendocrine Tumors EPO906 epothilone B - Carcinoid, Neuroendocrine Tumors | Phase 2 | Completed | Novartis Pharmaceuticals | 33 | 2002-07-01 | 2017-03-01 |
| EPO906 Therapy in Patients With Advanced Colorectal Cancer epothilone b - Colorectal Neoplasms, Colonic Neoplasms | Phase 2 | Completed | Novartis Pharmaceuticals | 62 | 2002-05-01 | 2013-12-04 |
| EPO906 Therapy in Patients With Advanced Kidney Cancer epothilone b - Kidney Neoplasms | Phase 2 | Completed | Novartis Pharmaceuticals | 53 | 2002-04-01 | 2012-04-17 |
| EPO906 Therapy in Patients With Advanced Melanoma epothilone b - Melanoma | Phase 2 | Completed | Novartis Pharmaceuticals | 51 | 2002-03-01 | 2012-04-25 |
| EPO906 Therapy in Patients With Advanced Breast Cancer epothilone b - Breast Neoplasms | Phase 2 | Completed | Novartis Pharmaceuticals | 46 | 2002-01-01 | 2017-02-08 |
| EPO906 Therapy in Patients With Prostate Cancer epothilone b - Prostatic Neoplasms | Phase 2 | Completed | Novartis Pharmaceuticals | 48 | 2002-01-01 | 2017-02-09 |
| EPO906 Therapy in Patients With Advanced Ovarian, Primary Fallopian, or Primary Peritoneal Cancer epothilone b - Ovarian Neoplasms, Peritoneal Neoplasms | Phase 2 | Completed | Novartis Pharmaceuticals | 54 | 2001-09-01 | 2012-04-16 |
Neoplasms (7) · Carcinoma (5) · Brain Neoplasms (3) · Neoplasm Metastasis (3) · Breast Neoplasms (2) · Carcinoma, Non-Small-Cell Lung (2) · Colonic Neoplasms (2) · Colorectal Neoplasms (2) · Lung Neoplasms (2) · Prostatic Neoplasms (2) · Breast Neoplasms, Male (1) · Carcinoid Tumor (1) · Carcinoma, Hepatocellular (1) · Fallopian Tube Neoplasms (1) · Gastrinoma (1)
Novartis Pharmaceuticals (11) · British Columbia Cancer Agency (1) · David Peereboom, MD (1) · University of Southern California (1) · University of Zurich (1)
United States (13) · Canada (2) · France (2) · Australia (1) · Belgium (1) · Germany (1) · Hong Kong (1) · Italy (1) · Netherlands (1) · Singapore (1) · Slovakia (1) · South Korea (1) · Spain (1) · Taiwan (1) · United Kingdom (1)
David M. Peereboom, MD (1) · Heinz-Josef Lenz, M.D. (1) · Joseph Baar, MD (1) · Kim Chi, MD (1) · Silvia Hofer, MD (1)
P30CA043703 (1)