5 terminated, 2 completed. 5 Phase 1, 3 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Terminated 3, Completed 2 |
| Phase 2 | 3 | Terminated 3 |
| Phase 3 | 1 | Terminated 1 |
Follow emvododstat: new trials by email Literature Review of emvododstat trials Research Report on emvododstat
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate Efficacy and Safety of PTC299 (Emvododstat) in Hospitalized Participants With Coronavirus (COVID-19) PTC299, SOC, Placebo - Pneumonia, COVID-19 | Phase 2 / Phase 3 | Terminated | PTC Therapeutics | 189 | 2020-07-09 | 2023-06-26 |
| Study of PTC299 (Emvododstat) in Relapsed/Refractory Acute Leukemias PTC299 - Leukemia, Myeloid, Acute, AML | Phase 1 | Terminated | PTC Therapeutics | 33 | 2018-10-29 | 2022-02-02 |
| PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors VEGF inhibitor PTC299 - Brain and Central Nervous System Tumors | Phase 1 | Completed | Pediatric Brain Tumor Consortium | 28 | 2010-11-01 | 2015-05-04 |
| PTC299 for Treatment of Neurofibromatosis Type 2 PTC299 - Neurofibromatosis 2 | Phase 2 | Terminated | PTC Therapeutics | 11 | 2009-07-31 | 2019-04-12 |
| PTC299 in Treating Patients With HIV-Related Kaposi Sarcoma VEGF inhibitor PTC299, gene expression analysis, polymerase chain reaction - Kaposi's Sarcoma | Phase 1 / Phase 2 | Terminated | AIDS Malignancy Consortium | 17 | 2008-09-01 | 2018-06-06 |
| PTC299 for Treatment of Advanced Cancer PTC299, Docetaxel - Advanced Cancer | Phase 1 | Terminated | PTC Therapeutics | 76 | 2008-07-03 | 2019-05-10 |
| PTC299 and Hormonal Agent for Treatment of Metastatic Breast Cancer PTC299 - Metastatic Breast Cancer | Phase 1 | Completed | PTC Therapeutics | 33 | 2007-11-01 | 2016-03-03 |
Neoplasms (2) · AIDS-related Kaposi sarcoma (1) · Astrocytoma (1) · Breast Neoplasms (1) · COVID-19 (1) · Central Nervous System Neoplasms (1) · Coronavirus Infections (1) · Familial ependymoma (1) · HIV Infections (1) · Leukemia, Myeloid (1) · Leukemia, Myeloid, Acute (1) · Medulloblastoma (1) · Meningioma (1) · Neoplasms by Histologic Type (1) · Neurofibromatoses (1)
PTC Therapeutics (5) · AIDS Malignancy Consortium (1) · Pediatric Brain Tumor Consortium (1)
United States (7) · Australia (1) · Belgium (1) · Brazil (1) · Colombia (1) · France (1) · Mexico (1) · Poland (1) · Portugal (1) · South Africa (1) · Spain (1)
Jay Barth, MD (2) · Gary Schwartz, MD (1) · Quintus Ngumah, OD, PhD (1) · Roger J. Packer, MD (1) · Susan E. Krown, MD (1)
U01CA081457 (1), U01CA121947 (1)